6,2',4'-TRIMETHOXYFLAVONE

Product Name
6,2',4'-TRIMETHOXYFLAVONE
CAS No.
720675-90-1
Chemical Name
6,2',4'-TRIMETHOXYFLAVONE
Synonyms
Trimethoxyflavone;6,2',4'-Trimethoxyflavone;6,2',4'-TRIMETHOXYFLAVONE;2',4',6-Trimethoxyflavone;2-(2,4-Dimethoxyphenyl)-2,3-dihydro-6-methoxy-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 2-(2,4-dimethoxyphenyl)-2,3-dihydro-6-methoxy-
CBNumber
CB4137595
Molecular Formula
C18H18O5
Formula Weight
314.33
MOL File
Mol file
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6,2',4'-TRIMETHOXYFLAVONE Property

Boiling point:
482.8±45.0 °C(Predicted)
Density 
1.208±0.06 g/cm3(Predicted)
storage temp. 
room temp
solubility 
DMSO: >5mg/mL
form 
powder
color 
yellow
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Safety

Hazard Codes 
T
Risk Statements 
25
Safety Statements 
45
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
T4080
Product name
6, 2′, 4′-trimethoxyflavone
Purity
≥98% (HPLC)
Packaging
10mg
Price
$90.5
Updated
2024/03/01
Sigma-Aldrich
Product number
T4080
Product name
6, 2′, 4′-trimethoxyflavone
Purity
≥98% (HPLC)
Packaging
50mg
Price
$347
Updated
2024/03/01
American Custom Chemicals Corporation
Product number
CBL0001131
Product name
6, 2′, 4′-trimethoxyflavone
Purity
95.00%
Packaging
250MG
Price
$238.35
Updated
2021/12/16
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6,2',4'-TRIMETHOXYFLAVONE Chemical Properties,Usage,Production

Biochem/physiol Actions

6, 2′, 4′-trimethoxyflavone is a selective aryl hydrocarbon receptor (AHR) antagonist with no partial agonist activity. The role of the transcription factor aryl hydrocarbon receptor (AHR) in biology is still under evaluation and has expanded beyond that of a xenobiotic sensor and regulator of detoxification. Inhibition of AHR activity by antagonists could result in anti-inflammatory actions. 6, 2′, 4′-trimethoxyflavone (TMF) is a pure AHR antagonist. The compound compete with agonists, such as 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin (TCDD) and benzo[a]pyrene (B[a]P), thus effectively inhibiting AHRmediated transactivation of a heterologous reporter and endogenous targets e.g. CYP1A1. TMF also exhibits no species or promoter dependency with regard to AHR antagonism. Thus it represents an improved tool allowing for more precise dissection of AHR function.

6,2',4'-TRIMETHOXYFLAVONE Preparation Products And Raw materials

Raw materials

Preparation Products

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6,2',4'-TRIMETHOXYFLAVONE Suppliers

China 5 United Kingdom 2 United States 3 Global 10
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Sigma-Aldrich
Tel
021-61415566 800-8193336
Email
orderCN@merckgroup.com
Country
China
ProdList
51456
Advantage
80
Shanghai Weiwei Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
sales@wheybio.com
Country
CHINA
ProdList
4398
Advantage
58
Shanghai Yijie Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
SHYIJIEBIO@126.COM
Country
CHINA
ProdList
3510
Advantage
58
Shanghai Haoyang Biological Technology Co., Ltd.
Tel
--
Fax
--
Email
596799915@QQ.COM
Country
CHINA
ProdList
2905
Advantage
58

720675-90-1, 6,2',4'-TRIMETHOXYFLAVONERelated Search:


  • 6,2',4'-TRIMETHOXYFLAVONE
  • Trimethoxyflavone
  • 2',4',6-Trimethoxyflavone
  • 2-(2,4-Dimethoxyphenyl)-2,3-dihydro-6-methoxy-4H-1-benzopyran-4-one
  • 4H-1-Benzopyran-4-one, 2-(2,4-dimethoxyphenyl)-2,3-dihydro-6-methoxy-
  • 6,2',4'-Trimethoxyflavone
  • 720675-90-1