1-deazaadenosine

Product Name: 1-deazaadenosine
CAS No.: 14432-09-8
Chemical Name: 1-deazaadenosine
Synonyms: 1-deazaadenosine;Deazaadenosine, 1-;1 Deazaadenosine,1Deazaadenosine;3-β-D-Ribofuranosyl-3H-imidazo[4,5-b]pyridin-7-amine;3H-Imidazo[4,5-b]pyridin-7-amine, 3-β-D-ribofuranosyl-;3H-IMidazo[4,5-b]pyridin-7-aMine, 3-b-D-ribofuranosyl-;3-beta-D-Ribofuranosyl-3H-imidazo[4,5-b]pyridin-7-amine;7-Amino-3-(β-D-ribofuranosyl)-3H-imidazo[4,5-b]pyridine
CBNumber: CB41392102
Molecular Formula: C11H14N4O4
Formula Weight: 266.25326
MOL File: 14432-09-8.mol

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1-deazaadenosine Property

Melting point:: 263-264 °C (decomp)(Solv: water (7732-18-5))
Boiling point:: 674.6±65.0 °C(Predicted)
Density: 1.90±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble to 25 mM in DMSO
form: Powder
pka: 13.21±0.70(Predicted)
color: White to off-white
InChI: InChI=1/C11H14N4O4/c12-5-1-2-13-10-7(5)14-4-15(10)11-9(18)8(17)6(3-16)19-11/h1-2,4,6,8-9,11,16-18H,3H2,(H2,12,13)/t6-,8-,9-,11-/s3
InChIKey: NVUDDRWKCUAERS-SOMIAQKHNA-N
SMILES: C12N([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)C=NC1=C(N)C=CN=2 |&1:2,4,7,9,r|

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 4488
Product name: 1-Deazaadenosine
Purity: ≥98%(HPLC)
Packaging: 10
Price: $280
Updated: 2021/12/16

TRC

Product number: D203228
Product name: 1-Deazaadenosine
Packaging: 2.5mg
Price: $330
Updated: 2021/12/16

Usbiological

Product number: 254328
Product name: 1-Deazaadenosine
Packaging: 10mg
Price: $588
Updated: 2021/12/16

Axon Medchem

Product number: Axon2434
Product name: 1-Deazaadenosine
Purity: 99%
Packaging: 5mg
Price: $148.5
Updated: 2021/12/16

ApexBio Technology

Product number: B5619
Product name: 1-Deazaadenosine
Packaging: 10mg
Price: $417
Updated: 2021/12/16

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1-deazaadenosine Chemical Properties,Usage,Production

Uses

1-Deazaadenosine is a potent Adenosine deaminase (ADA) inhibitor with a Ki value of 0.66 μM. 1-Deazaadenosine exhibits anti-cancer activities in vitro and has the potential to be a chemotherapy agent for lymphoproliferative disorders[1][2].

storage

Store at +4°C

References

[1] Cristalli G, et al.Adenosine deaminase inhibitors: Structure-activity relationships in 1-deazaadenosine and erythro-9-(2-hydroxy-3-nonyl)adenine analogues. Drug Dev.Res.
[2] Cristalli G, et al.Improved synthesis and antitumor activity of 1-deazaadenosine.J Med Chem. 1987 Sep;30(9):1686-8. DOI:10.1021/jm00392a029

1-deazaadenosine Preparation Products And Raw materials

Raw materials

Preparation Products

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14432-09-8