ChemicalBook > CAS DataBase List > N-desmethylquazepam
N-desmethylquazepam
- Product Name
- N-desmethylquazepam
- CAS No.
- 1645-32-5
- Chemical Name
- N-desmethylquazepam
- Synonyms
- Desalkylquazepam;N-desmethylquazepam;7-chloro-5-(2-fluorophenyl)-1H-benzo[e][1,4]diazepine-2(3H)-thione;2H-1,4-Benzodiazepine-2-thione, 7-chloro-5-(2-fluorophenyl)-1,3-dihydro-
- CBNumber
- CB41393518
- Molecular Formula
- C15H10ClFN2S
- Formula Weight
- 304.77
- MOL File
- 1645-32-5.mol
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N-desmethylquazepam Property
- Melting point:
- 212-214 °C(Solv: water (7732-18-5); chloroform (67-66-3); methanol (67-56-1))
- Boiling point:
- 410.2±55.0 °C(Predicted)
- Density
- 1.39±0.1 g/cm3(Predicted)
- solubility
- DMF: 30 mg/ml; DMSO: 20 mg/ml; Ethanol: Slightly soluble; PBS (pH 7.2): 0.30 mg/ml
- form
- A crystalline solid
- pka
- 9.55±0.40(Predicted)
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N-desmethylquazepam Chemical Properties,Usage,Production
Uses
Desalkylquazepam (Compound 23; N-Desmethylquazepam) is a precursor in the synthesis of triazolobenzodiazepines[1].
References
[1] Hester JB Jr, et al. 6-phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepines which have central nervous system depressant activity. J Med Chem. 1971 Nov;14(11):1078-81. DOI:10.1021/jm00293a015
N-desmethylquazepam Preparation Products And Raw materials
Raw materials
Preparation Products
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