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beta-endorphin (6-31)

Product Name
beta-endorphin (6-31)
CAS No.
77761-27-4
Chemical Name
beta-endorphin (6-31)
Synonyms
beta-endorphin (6-31);6-31-β-Endorphin (human);b-Lipotropin (64-89) (huMan);4 β-Endorphin (6-31) (human);β-Lipotropin (64-89) (human);6-31-b-Endorphin (sheep),27-L-tyrosine-31-L-glutamic acid;6-31-β-Endorphin (sheep), 27-L-tyrosine-31-L-glutamic acid-;H-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-Tyr-Lys-Lys-Gly-Glu-OH
CBNumber
CB41394797
Molecular Formula
C131H218N34O40
Formula Weight
2909.36
MOL File
77761-27-4.mol
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beta-endorphin (6-31) Property

Boiling point:
2671.5±65.0 °C(Predicted)
Density 
1.294±0.06 g/cm3(Predicted)
Sequence
Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr-Leu-Phe-Lys-Asn-Ala-Ile-Ile-Lys-Asn-Ala-Tyr-Lys-Lys-Gly-Glu
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biorbyt Ltd
Product number
orb364362
Product name
Beta-Endorphin (6-31)
Purity
> 95%
Packaging
1mg
Price
$479.4
Updated
2021/12/16
Biorbyt Ltd
Product number
orb364362
Product name
Beta-Endorphin (6-31)
Purity
> 95%
Packaging
5mg
Price
$1016.6
Updated
2021/12/16
Biorbyt Ltd
Product number
orb364362
Product name
Beta-Endorphin (6-31)
Purity
> 95%
Packaging
10mg
Price
$1518.1
Updated
2021/12/16
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beta-endorphin (6-31) Chemical Properties,Usage,Production

Uses

β-Endorphin, an endogenous opioid neuropeptide, is an opioid receptor agonist. β-Endorphin binds preferentially to μ-opioid receptors and is produced in certain neurons of the central and peripheral nervous system and is one of three endorphins produced in humans. β-Endorphin can be used to reduce stress and maintain homeostasis in the body and is involved in neurological pain perception regulation[1].

in vivo

β-Endorphin (0.03 to 1.00?μg/kg, i.p., once) impairs retention of a one-trial inhibitory avoidance task in a dose-dependent manner in male Swiss mice immediately post-training. Also, it works in the process of memory consolidation[1].

Animal Model:Adult male Swiss mice (22-25 g)[1]
Dosage:0.03, 0.10, 0.30 or 1.00 μg/kg
Administration:i.p., once
Result:Significantly impaired retention at the doses of 0.03 and 0.10?μg/kg while not significantly affect retention as compared with the control group at the two higher doses of 0.30 and 1.00?μg/kg , but tended to increase retention as compared with the dose of 0.10?μg/kg.
Increased latencies to step-through at the two higher doses of 0.30 and 1.00?μg/kg but no effect at lower doses.

References

[1] Introini IB, et al. The impairment of retention induced by beta-endorphin in mice may be mediated by a reduction of central cholinergic activity. Behav Neural Biol. 1984 Jul;41(2):152-63. DOI:10.1016/s0163-1047(84)90527-2

beta-endorphin (6-31) Preparation Products And Raw materials

Raw materials

Preparation Products

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beta-endorphin (6-31) Suppliers

China 40 United States 1 Global 41
Chemsky (shanghai) International Co.,Ltd
Tel
021-50135380
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shchemsky@sina.com
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China
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15402
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BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
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United States
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Nanjing Leon Biological Technology Co., Ltd.
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17705183659
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Nanjing Peptide Biotech Ltd.
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025-58361106-805 15951641583
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zhao.xu@njpeptide.com
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Chengdu Youngshe Chemical Co., Ltd.
Tel
+86-17380623303
Fax
028-62328193
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Hangzhou Peptidego Biotech Co.,Ltd.
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Nanjing chengqimei Biotechnology Co., Ltd
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Nanjing TGpeptide Biotechnology Co.,Ltd.
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77761-27-4, beta-endorphin (6-31)Related Search:

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