INTERMEDINE

Product Name: INTERMEDINE
CAS No.: 10285-06-0
Chemical Name: INTERMEDINE
Synonyms: C10330;INTERMIDINE;(+)-Intermedine;9-(+)-Trachelanthylretronecine;(1R)-2,3,5,7aβ-Tetrahydro-7-[[(2S,3R)-2-isopropyl-2,3-dihydroxybutyryl]oxymethyl]-1H-pyrrolizine-1-ol;(2S,3R)-2,3-Dihydroxy-2-isopropylbutanoic acid [[(5R,6R)-6-hydroxy-1-azabicyclo[3.3.0]oct-3-en-4-yl]methyl] ester;Butanoic acid, 2,3-dihydroxy-2-(1-methylethyl)-, [(1R,7aR)-2,3,5,7a-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl]methyl ester, (2S,3R)-
CBNumber: CB41405433
Molecular Formula: C15H25NO5
Formula Weight: 299.36
MOL File: 10285-06-0.mol

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INTERMEDINE Property

Melting point:: 140-141 °C
Boiling point:: 463.3±45.0 °C(Predicted)
Density: 1.26±0.1 g/cm3(Predicted)
pka: 12.59±0.29(Predicted)

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Safety

RIDADR: 1544
HazardClass: 6.1(b)
PackingGroup: III

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: I666660
Product name: Intermedine
Packaging: 0.5mg
Price: $260
Updated: 2021/12/16

TRC

Product number: I666660
Product name: Intermedine
Packaging: 5mg
Price: $2080
Updated: 2021/12/16

Biosynth Carbosynth

Product number: XI161638
Product name: Intermedine
Packaging: 1mg
Price: $200
Updated: 2021/12/16

Biosynth Carbosynth

Product number: XI161638
Product name: Intermedine
Packaging: 2mg
Price: $300
Updated: 2021/12/16

Biosynth Carbosynth

Product number: XI161638
Product name: Intermedine
Packaging: 5mg
Price: $500
Updated: 2021/12/16

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INTERMEDINE Chemical Properties,Usage,Production

Uses

Intermedine-D7 is a labelled analogue of Intermedine (I666660). Intermedine is an unsaturated monoester pyrrolizidine alkaloid that is extracted from the seeds of Amsinckia intermedia, a tarweed that causes enzootic hepatic cirrhosis in horses and hard liver disease in cattle. Intermedine is also a diastereomer of Lycopsamine (L487525), a pyrrolizidine alkaloid that is found in honey and in comfrey (a topical anti-inflammatory agent used to treat patients with arthritis and gout).

Definition

ChEBI: A carboxylic ester compound formed from condensation between retronecine and (2S,3R)-2,3-dihydroxy-2-isopropylbutanoic acid.

INTERMEDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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INTERMEDINE Suppliers

China 27 France 1 India 1 United Kingdom 1 United States 1 Global 31

J & K SCIENTIFIC LTD.

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EMMX Biotechnology LLC

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Nanjing Digger Medical Technology Co. Ltd.

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10285-06-0, INTERMEDINERelated Search:

retronecine INTERMEDINE SUPININE

INTERMIDINE

(1R)-2,3,5,7aβ-Tetrahydro-7-[[(2S,3R)-2-isopropyl-2,3-dihydroxybutyryl]oxymethyl]-1H-pyrrolizine-1-ol

(2S,3R)-2,3-Dihydroxy-2-isopropylbutanoic acid [[(5R,6R)-6-hydroxy-1-azabicyclo[3.3.0]oct-3-en-4-yl]methyl] ester

9-(+)-Trachelanthylretronecine

C10330

Butanoic acid, 2,3-dihydroxy-2-(1-methylethyl)-, [(1R,7aR)-2,3,5,7a-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl]methyl ester, (2S,3R)-

(+)-Intermedine

10285-06-0