SELENO-DL-CYSTINE

SELENO-DL-CYSTINE Property

Melting point:

214.5°C

Boiling point:

133.5°C

storage temp. 

-20°C

pka

1.69±0.10(Predicted)

form 

powder

color 

yellow to brown

Safety

Hazard Codes 

T,N

Risk Statements 

23/25-33-50/53

Safety Statements 

20/21-28-45-60-61

RIDADR 

UN 2811 6.1/PG 3

WGK Germany 

3

RTECS 

AY6031000

HazardClass 

6.1(a)

PackingGroup 

II

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H373May cause damage to organs through prolonged or repeated exposure

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P273Avoid release to the environment.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P314Get medical advice/attention if you feel unwell.

SELENO-DL-CYSTINE Chemical Properties,Usage,Production

Uses

Selenocystine is a broad-spectrum anti-cancer agent. Selenocystine induces DNA damage in HepG2 cells, particularly in the form of DNA double strand breaks (DSBs). Selenocystine exhibits great promise as a therapeutic or adjuvant agent targeting DNA repair for cancer treatment[1].

Definition

ChEBI: Selenocystine is a diselenide and a selenoamino acid. It is functionally related to a selenocysteine.

References

[1] Eva Ari Wahyuni, et al. Selenocystine induces oxidative-mediated DNA damage via impairing homologous recombination repair of DNA double-strand breaks in human hepatoma cells. Chem Biol Interact. 2022 Sep 25:365:110046. DOI:10.1016/j.cbi.2022.110046