ChemicalBook > CAS DataBase List > N-ISOBUTYL-2,6,8-DECATRIENAMIDE

N-ISOBUTYL-2,6,8-DECATRIENAMIDE

Product Name: N-ISOBUTYL-2,6,8-DECATRIENAMIDE
CAS No.: 25394-57-4
Chemical Name: N-ISOBUTYL-2,6,8-DECATRIENAMIDE
Synonyms: AFFININ;SPILANTHOL;SPILANTHOL(P);Spilanthol (Affinin);spilanthol(25394-57-4);Spilanthol (Technical Grade);N-ISOBUTYL-2,6,8-DECATRIENAMIDE;Nano-Liposomal ACMELLA OLERACEA EXTRACT;(2E,6Z,8E)-N-Isobutyl-2,6,8-decatrienamide;2,6,8-DecatrienaMide,N-(2-Methylpropyl)-, (2E,6Z,8E)-
CBNumber: CB41434697
Molecular Formula: C14H23NO
Formula Weight: 221.34
MOL File: 25394-57-4.mol

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N-ISOBUTYL-2,6,8-DECATRIENAMIDE Property

Melting point:: 23°
Boiling point:: bp0.2 141°; bp0.3-0.5 160-165°
Density: 0.896±0.06 g/cm3(Predicted)
refractive index: nD25 1.5134
FEMA: 4668 | (2E,6E/Z,8E)-N-(2-METHYLPROPYL)-2,6,8-DECATRIENAMIDE
storage temp.: Amber Vial, -86°C Freezer, Under inert atmosphere
solubility: Chloroform (Slightly), Methanol (Slightly)
pka: 15.07±0.46(Predicted)
form: Solid
color: Colourless to Yellow Oil
Odor: at 100.00 %. fruity
Odor Type: fruity
JECFA Number: 2077
Stability:: Light Sensitive, Temperature Sensitive
LogP: 3.18

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Safety

Toxicity: LD50 oral in mouse: 4378mg/kg

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: S681850
Product name: SpilantholAmixtureof(2E,6Z,8E)>80%;(2E,6E,8E);and(2E,6Z,8Z)
Packaging: 1mg
Price: $205
Updated: 2021/12/16

TRC

Product number: S681850
Product name: SpilantholAmixtureof(2E,6Z,8E)>80%;(2E,6E,8E);and(2E,6Z,8Z)
Packaging: 10mg
Price: $1620
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 48719
Product name: Spilanthol
Packaging: 50mg
Price: $2200
Updated: 2021/12/16

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N-ISOBUTYL-2,6,8-DECATRIENAMIDE Chemical Properties,Usage,Production

Uses

Spilanthol is a fatty acid amide isolated from Acmella oleracea. Spilanthol extract has been discovered to aid in saliva stimulation (sialogogue) for people suffering from dry mouth (xerostomia).

Uses

Insecticide synergist.

Synthesis Reference(s)

Tetrahedron Letters, 25, p. 5177, 1984 DOI: 10.1016/S0040-4039(01)81556-2

in vivo

Spilanthol ( 1-1.875 mg/kg, Ip, Once) shows antinociceptive activity in acetic acid-induced abdominal writhes Male ICR mice model and capsaicin-induced licking paw Male ICR mice model^[2].
Spilanthol (30 mg/kg, Po, Once a day for four days) a protective effect against the intestinal damage associated in swiss mice model of intestinal mucositis induced by 5-fluorouracil (HY-90006)^[4].
Spilanthol (800 mg/kg, Po, Once) has a diuretic effect in adult C57BL/6J male mice^[5].

Animal Model:	Acetic acid-induced abdominal writhes Male ICR mice model^[2]
Dosage:	1-1.875 mg/kg
Administration:	Intraperitoneal administration(i.p.), Once
Result:	As the dose increased, the number of abdominal contractions and licking behavior decreased, and a maximum antinociceptive effect of 46.67%

Animal Model:	Swiss mice model of intestinal mucositis induced by 5-fluorouracil^[4].
Dosage:	30 mg/kg
Administration:	Oral adminstraion(p.o.), Once a day for four days
Result:	Showed the intestinal wall recovery, villi are higher and less irregularity and high number and greater length of intestinal crypts.

Animal Model:	Adult C57BL/6J male mice^[5].
Dosage:	800 mg/Kg
Administration:	Oral adminstraion (p.o.), Once
Result:	Increased in urine output, sodium, and increased excretion of sodium, potassium and chloride.

N-ISOBUTYL-2,6,8-DECATRIENAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from N-ISOBUTYL-2,6,8-DECATRIENAMIDE manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: Spilanthol 25394-57-4
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 1-40%
Supply Ability: 100KG
Release date: 2025-09-11

25394-57-4, N-ISOBUTYL-2,6,8-DECATRIENAMIDERelated Search:

N-ISOBUTYL-2,6,8-DECATRIENAMIDE

SPILANTHOL

AFFININ

(2E,6Z,8E)-N-Isobutyl-2,6,8-decatrienamide

SPILANTHOL(P)

2,6,8-DecatrienaMide,N-(2-Methylpropyl)-, (2E,6Z,8E)-

spilanthol(25394-57-4)

2,6,8-Decatrienamide,N-(2-methylpropyl)-, (2E,6Z,8E)- CAS NO.25394-57-4

Nano-Liposomal ACMELLA OLERACEA EXTRACT

Spilanthol A mixture of (2E, 6Z, 8E) >80%, (2E, 6E, 8E), and (2E, 6Z, 8Z)

Spilanthol (Technical Grade)

Spilanthol (Affinin)

25394-57-4