Naphth[2,3,-b]oxiren-2(1aH)-one, 4,

Product Name: Naphth[2,3,-b]oxiren-2(1aH)-one, 4,
CAS No.: 27062-01-7
Chemical Name: Naphth[2,3,-b]oxiren-2(1aH)-one, 4,
Synonyms: Isonardosinone;Naphth[2,3,-b]oxiren-2(1aH)-one, 4,;(1aS)-4,5,6,6a,7,7aβ-Hexahydro-7α-(1-hydroxy-1-methylethyl)-6β,6aβ-dimethylnaphth[2,3-b]oxiren-2(1aβH)-one;Naphth[2,3-b]oxiren-2(1aH)-one, 4,5,6,6a,7,7a-hexahydro-7-(1-hydroxy-1-methylethyl)-6,6a-dimethyl-, (1aS,6R,6aR,7S,7aS)-
CBNumber: CB41449756
Molecular Formula: C15H22O3
Formula Weight: 250.33
MOL File: 27062-01-7.mol

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Naphth[2,3,-b]oxiren-2(1aH)-one, 4, Property

Boiling point:: 381.0±25.0 °C(Predicted)
Density: 1.15±0.1 g/cm3(Predicted)
pka: 14.68±0.29(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Arctom

Product number: CFN95180
Product name: Isonardosinone
Purity: ≥98%
Packaging: 10mg
Price: $318
Updated: 2021/12/16

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Naphth[2,3,-b]oxiren-2(1aH)-one, 4, Chemical Properties,Usage,Production

Uses

Isonardosinone is a nardosinone-type sesquiterpenes, which can be isolated from Valerianaceae. Isonardosinone inhibits NF-κB and MAPK signaling pathway, suppresses expression of iNOS and cyclooxygenase-2 (COX-2) in Lipopolysaccharides (HY-D1056)-induced BV2 microglia, exhibits anti-inflammatory activity[1].

References

[1] Ko W, et al., Nardosinone-Type Sesquiterpenes from the Hexane Fraction of Nardostachys jatamansi Attenuate NF-κB and MAPK Signaling Pathways in Lipopolysaccharide-Stimulated BV2 Microglial Cells. Inflammation. 2018 Aug;41(4):1215-1228. DOI:10.1007/s10753-018-0768-9

Naphth[2,3,-b]oxiren-2(1aH)-one, 4, Preparation Products And Raw materials

Raw materials

Preparation Products

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Naphth[2,3,-b]oxiren-2(1aH)-one, 4, Suppliers

China 10 United States 1 Global 11

Wuhan ChemFaces Biochemical Co., Ltd.

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Naphth[2,3-b]oxiren-2(1aH)-one, 4,5,6,6a,7,7a-hexahydro-7-(1-hydroxy-1-methylethyl)-6,6a-dimethyl-, (1aS,6R,6aR,7S,7aS)-

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