2-METHYL-QUINOLINE-3-CARBOXYLIC ACID
- Product Name
- 2-METHYL-QUINOLINE-3-CARBOXYLIC ACID
- CAS No.
- 635-79-0
- Chemical Name
- 2-METHYL-QUINOLINE-3-CARBOXYLIC ACID
- Synonyms
- Quinaldine-3-carboxylic acid;Synthesis of 2-Methylquinolin-3-amine;3-Quinolinecarboxylic acid, 2-methyl-;2-Methylquinoline-3-carboxylic acid 95%
- CBNumber
- CB41478657
- Molecular Formula
- C11H9NO2
- Formula Weight
- 187.19
- MOL File
- 635-79-0.mol
2-METHYL-QUINOLINE-3-CARBOXYLIC ACID Property
- Melting point:
- 251 °C
- Boiling point:
- 342.0±27.0 °C(Predicted)
- Density
- 1.285±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Room Temperature
- form
- solid
- pka
- 1.17±0.30(Predicted)
- color
- Light brown to brown
- InChI
- InChI=1S/C11H9NO2/c1-7-9(11(13)14)6-8-4-2-3-5-10(8)12-7/h2-6H,1H3,(H,13,14)
- InChIKey
- WXYKQNAKEPRCGF-UHFFFAOYSA-N
- SMILES
- N1C2C(=CC=CC=2)C=C(C(O)=O)C=1C
Safety
- HS Code
- 2933499090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M342340
- Product name
- 2-Methyl-quinoline-3-carboxylic acid
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- OR301188
- Product name
- 2-Methyl-quinoline-3-carboxylic acid
- Purity
- 95%
- Packaging
- 1g
- Price
- $269
- Updated
- 2021/12/16
- Product number
- 4H58-1-FX
- Product name
- 2-Methylquinoline-3-carboxylic acid
- Packaging
- 1g
- Price
- $296
- Updated
- 2021/12/16
- Product number
- 189193
- Product name
- 2-Methylquinoline-3-carboxylic acid
- Packaging
- 5g
- Price
- $630
- Updated
- 2021/12/16
- Product number
- CHM0021516
- Product name
- 2-METHYL-3-QUINOLINECARBOXYLIC ACID
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $808.89
- Updated
- 2021/12/16
2-METHYL-QUINOLINE-3-CARBOXYLIC ACID Chemical Properties,Usage,Production
Synthesis
15785-08-7
635-79-0
General procedure for the synthesis of 2-methyl-3-quinolinecarboxylic acid from ethyl 2-methylquinoline-3-carboxylate: to a stirred 60% aqueous ethanol solution (80 mL) of potassium hydroxide (4.489 g, 80 mmol) was added ethyl 2-methylquinoline-3-carboxylate (2.153 g, 10 mmol). The reaction mixture was stirred under reflux conditions for 1 hour. Upon completion of the reaction, the ethanol was evaporated under reduced pressure, followed by dilution with the addition of water (10 mL) and acidification with 1 M hydrochloric acid solution to pH < 7. The precipitate precipitated was collected and recrystallized by a solvent mixture of dichloromethane/hexane (1:10, v/v) to give 2-methyl-3-quinolinecarboxylic acid as a yellow solid in 92% yield (1.724 g, 9.2 mmol).
References
[1] Synthesis (Germany), 2013, vol. 45, # 23, p. 3239 - 3244
[2] Journal of Medicinal Chemistry, 2006, vol. 49, # 23, p. 6897 - 6907
2-METHYL-QUINOLINE-3-CARBOXYLIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
2-METHYL-QUINOLINE-3-CARBOXYLIC ACID Suppliers
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