jaconine Property

Melting point:

146 °C

Boiling point:

180 °C

Density 

1.36±0.1 g/cm3(Predicted)

pka

11.66±0.60(Predicted)

Safety

RIDADR 

1544

HazardClass 

6.1(b)

PackingGroup 

III

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P262Do not get in eyes, on skin, or on clothing.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

jaconine Chemical Properties,Usage,Production

Description

This alkaloid from Senecio Jacobea was originally given the empirical formula ClsH2S0sN by Barger and Blackie but has since been shown to exist as the chlorine-containing compound. It has[α] _D + 52.5° (CHCl3 ) and on hydrolysis yields retronecine and jaconecic acid, ClOH160 6, m.p. l83-4°C; [α]²⁵_D + 28.1 ° (EtOH). In this reaction, the chlorine is also lost by hydrolysis. The base forms a dihydrochloride, m.p. 204-5°C (dec.).

References

Manske., Can. J. Res., S, 651 (1931)
Barger, Blackie.,J. Chern. Soc., 584 (1937)
Adana et al., J. Arner. Chern. Soc., 78,3513 (1956)
Bradbury, Willis., Austral. J. Chern., 9,258 (1956)
Geissman., ibid, 12,247 (1959)