HOMOPTEROCARPIN
- Product Name
- HOMOPTEROCARPIN
- CAS No.
- 606-91-7
- Chemical Name
- HOMOPTEROCARPIN
- Synonyms
- 3,9-Dimethoxypterocarpan;(6aR)-6a,11aα-Dihydro-3,9-dimethoxy-6H-benzofuro[3,2-c][1]benzopyran;(6aR)-6aα,11aα-Dihydro-3,9-dimethoxy-6H-benzofuro[3,2-c][1]benzopyran;6H-Benzofuro[3,2-c][1]benzopyran, 6a,11a-dihydro-3,9-dimethoxy-, (6aR,11aR)-
- CBNumber
- CB41484900
- Molecular Formula
- C17H16O4
- Formula Weight
- 284.31
- MOL File
- 606-91-7.mol
HOMOPTEROCARPIN Property
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Oil
N-Bromosuccinimide Price
- Product number
- CFN97720
- Product name
- Homopterocarpin
- Packaging
- 5mg
- Price
- $463
- Updated
- 2021/12/16
- Product number
- CD32000849
- Product name
- Homopterocarpin
- Purity
- 95+%
- Packaging
- 5mg
- Price
- $730
- Updated
- 2021/12/16
HOMOPTEROCARPIN Chemical Properties,Usage,Production
Description
Homopterocarpin and Pterocarpus extract offer gastroprotection against indomethacin- induced ulcer by antioxidative mechanism and the modulation of gastric homeostasis, homopterocarpin may be responsible for, or contribute to the antiulcerogenic property of P. erinaceus. Homopterocarpin can inhibit (lower concentration) or kill (higher concntration) human^s liver cancer cells under the cultured condition, they have anticancer activity. 3. Homopterocarpin can contribute to the hepatoprotective and antioxidant potentials of P. erinaceus extract in acetaminophen-provoked hepatotoxicity. 4. (-)-Homopterocarpin has active insect antifeedant against both S. litura and R. speratus. 5. (+)-Homopterocarpin has antimitotic effect.
Uses
Homopterocarpin is an isoflavonoid that can be isolated from Pterocarpus erinaceus. Homopterocarpin has hepatoprotective and antioxidant properties. Homopterocarpin is a competitive reversible inhibitor of human monoamine oxidase-B with an IC50 and a Ki of 0.72 and 0.21 μM for hMAO-B, respectively. Homopterocarpin can be used for the research of liver injury and oxidative stress[1][2].
Definition
ChEBI: (6aR,11aR)-3,9-dimethoxy-6a,11a-dihydro-6H-benzofuro[3,2-c][1]benzopyran is a member of pterocarpans.
target
Antifection
References
[1] Akinmoladun AC, et al. Effect of homopterocarpin, an isoflavonoid from Pterocarpus erinaceus, on indices of liver injury and oxidative stress in acetaminophen-provoked hepatotoxicity. J Basic Clin Physiol Pharmacol. 2015 Nov;26(6):555-62. DOI:10.1515/jbcpp-2014-0095
[2] Oh JM, et al. Medicarpin and Homopterocarpin Isolated from Canavalia lineata as Potent and Competitive Reversible Inhibitors of Human Monoamine Oxidase-B. Molecules. 2022 Dec 28;28(1):258. DOI:10.3390/molecules28010258
HOMOPTEROCARPIN Preparation Products And Raw materials
Raw materials
Preparation Products
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