Uses
ChemicalBook > CAS DataBase List > 2-Amino-5-ethyl-pyridine

2-Amino-5-ethyl-pyridine

Uses
Product Name
2-Amino-5-ethyl-pyridine
CAS No.
19842-07-0
Chemical Name
2-Amino-5-ethyl-pyridine
Synonyms
5-ethylpyridin-2-aMine;5-ethyl-2-PyridinaMine;2-Pyridinamine, 5-ethyl-;2-Amino-5-ethyl-pyridine;5-ETHYL-PYRIDIN-2-YLAMINE;2-Amino-5-ethyl-pyridine ISO 9001：2015 REACH
CBNumber
CB41501267
Molecular Formula
C7H10N2
Formula Weight
122.17
MOL File
19842-07-0.mol
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2-Amino-5-ethyl-pyridine Property

Boiling point:
90-92 °C(Press: 3 Torr)
Density 
1.037±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,Room temperature
pka
7.06±0.13(Predicted)
Appearance
Light yellow to brown Liquid
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Safety

HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
B439585
Product name
5-ethylpyridin-2-amine
Packaging
50mg
Price
$110
Updated
2021/12/16
Apolloscientific
Product number
OR301037
Product name
2-Amino-5-ethyl-pyridine
Packaging
1g
Price
$531
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0094319
Product name
2-PYRIDINAMINE, 5-ETHYL-
Purity
95.00%
Packaging
2G
Price
$1674.75
Updated
2021/12/16
AK Scientific
Product number
Y5080
Product name
2-Amino-5-ethyl-pyridine
Packaging
25g
Price
$2175
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0094319
Product name
2-PYRIDINAMINE, 5-ETHYL-
Purity
95.00%
Packaging
5G
Price
$2607.41
Updated
2021/12/16
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2-Amino-5-ethyl-pyridine Chemical Properties,Usage,Production

Uses

5-Ethylpyridin-2-ylamine is a heterocyclic organic compound that can be used as a pharmaceutical intermediate.

Synthesis

1072-97-5

557-20-0

19842-07-0

General procedure for the synthesis of 5-ethylpyridin-2-amine from 2-amino-5-bromopyridine and diethylzinc: diethylzinc (24 mL, 1 M hexane solution, 24 mmol) was slowly added dropwise to a solution containing 2-amino-5-bromopyridine (2.0 g, 11.6 mmol) and Pd(dppf)Cl2-CH2Cl2 (225 mg, 0.28 mmol) in a degassed dioxane (45 mL) in solution. The reaction mixture was stirred at room temperature for 2 hours, followed by heating and refluxing for 3 hours and continued stirring at room temperature for 70 hours under argon protection. Upon completion of the reaction, the mixture was poured into saturated aqueous sodium chloride solution (150 mL) and extracted with ethyl acetate (4 x 100 mL). The organic phases were combined, washed with saturated aqueous sodium chloride solution (100 mL), dried over anhydrous sodium sulfate and concentrated under reduced pressure. The crude product was purified by column chromatography (ethyl acetate/heptane followed by methanol/ethyl acetate) to afford the target compound 5-ethylpyridin-2-amine. Yield: 1.40 g (99%).1H NMR (DMSO-d6, 400 MHz) δ 7.74 (s, 1H), 7.25 (dd, 1H), 6.40 (d, 1H), 5.67 (br.s, 2H), 2.39 (q, 2H), 1.10 (t, 3H).

References

[1] Patent: WO2007/51981, 2007, A1. Location in patent: Page/Page column 60
[2] Patent: WO2007/51982, 2007, A1. Location in patent: Page/Page column 52

2-Amino-5-ethyl-pyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 2-Amino-5-ethyl-pyridine manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
5-ETHYL-PYRIDIN-2-YLAMINE 19842-07-0
Price
US $1.80-7.80/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-06-18
Shaanxi Dideu Medichem Co. Ltd
Product
2-Amino-5-ethyl-pyridine 19842-07-0
Price
US $1.10/g
Min. Order
1g
Purity
99.0% min
Supply Ability
100 tons min
Release date
2021-05-12
Career Henan Chemical Co
Product
2-Amino-5-ethyl-pyridine 19842-07-0
Price
US $5.50/KG
Min. Order
1KG
Purity
99%
Supply Ability
1kg-100kg
Release date
2020-01-10

19842-07-0, 2-Amino-5-ethyl-pyridineRelated Search:

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  • 2-Amino-5-ethyl-pyridine
  • 5-ETHYL-PYRIDIN-2-YLAMINE
  • 5-ethyl-2-PyridinaMine
  • 5-ethylpyridin-2-aMine
  • 2-Pyridinamine, 5-ethyl-
  • 2-Amino-5-ethyl-pyridine ISO 9001：2015 REACH
  • 19842-07-0
  • pharmacetical