3-Bromo-2-iodo-thiophene
- Product Name
- 3-Bromo-2-iodo-thiophene
- CAS No.
- 60404-24-2
- Chemical Name
- 3-Bromo-2-iodo-thiophene
- Synonyms
- TH-I-Br;3-Bromo-2-iodo-thiophene;Thiophene, 3-bromo-2-iodo-;3-Bromo-2-iodothiophene 95+%
- CBNumber
- CB41558751
- Molecular Formula
- C4H2BrIS
- Formula Weight
- 288.93
- MOL File
- 60404-24-2.mol
3-Bromo-2-iodo-thiophene Property
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- Appearance
- Colorless to light yellow Liquid
Safety
- HS Code
- 2934999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 5H55-S-01
- Product name
- 3-Bromo-2-iodothiophene
- Packaging
- 100mg
- Price
- $136
- Updated
- 2021/12/16
- Product number
- 9000AB
- Product name
- 3-Bromo-2-iodothiophene
- Packaging
- 100mg
- Price
- $181
- Updated
- 2021/12/16
- Product number
- 5H55-S-01
- Product name
- 3-Bromo-2-iodothiophene
- Packaging
- 250mg
- Price
- $218
- Updated
- 2021/12/16
- Product number
- 9000AB
- Product name
- 3-Bromo-2-iodothiophene
- Packaging
- 250mg
- Price
- $254
- Updated
- 2021/12/16
- Product number
- 093866
- Product name
- 3-Bromo-2-iodothiophene
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $341
- Updated
- 2021/12/16
3-Bromo-2-iodo-thiophene Chemical Properties,Usage,Production
Synthesis
872-31-1
60404-24-2
General procedure for the synthesis of 3-bromo-2-iodothiophene from 3-bromothiophene: In a 100 ml four-necked flask, 3-bromothiophene (10 g, 61.3 mmol), iodine (5.61 g, 22.1 mmol), iodic acid (2.27 g, 12.9 mmol), acetic acid (20 ml), cyclohexane (30 ml), water (8 ml) and concentrated sulfuric acid (0.4 mL). The reaction mixture was stirred at 40°C for 17 hours. After completion of the reaction, the mixture was cooled to room temperature and then extracted by adding saturated aqueous sodium bicarbonate (40 mL) and diethyl ether (30 mL). The organic phase was washed sequentially with aqueous sodium hydroxide-sodium sulfite solution (30 mL) and saturated sodium chloride solution (30 mL) for 10 min each. The washed organic phase was dried with magnesium sulfate, filtered and concentrated. The crude product obtained was purified by distillation under reduced pressure (about 125 °C/9 torr) to give 3-bromo-2-iodothiophene (15.6 g, 88% yield) as an almost colorless liquid.
References
[1] Patent: JP6007631, 2016, B2. Location in patent: Paragraph 0032
[2] Synthesis (Germany), 2015, vol. 47, # 24, p. 3901 - 3906
[3] Organic Letters, 2013, vol. 15, # 18, p. 4666 - 4669
[4] Patent: KR2017/26286, 2017, A. Location in patent: Paragraph 0105-0109
3-Bromo-2-iodo-thiophene Preparation Products And Raw materials
Raw materials
Preparation Products
3-Bromo-2-iodo-thiophene Suppliers
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