ChemicalBook > CAS DataBase List > 4-Methanesulfonyl-piperidine

4-Methanesulfonyl-piperidine

Product Name
4-Methanesulfonyl-piperidine
CAS No.
290328-55-1
Chemical Name
4-Methanesulfonyl-piperidine
Synonyms
EOS-61037;4-Methanesulfonyl-piperidine;4-(Methylsulfonyl)piperid...;Piperidine, 4-(Methylsulfonyl)-;4-Methanesulfonylpiperidine hydrochloride;4-(methylsulfonyl)piperidine hydrochloride
CBNumber
CB41559581
Molecular Formula
C6H13NO2S
Formula Weight
163.24
MOL File
290328-55-1.mol
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4-Methanesulfonyl-piperidine Property

Boiling point:
336.9±31.0 °C(Predicted)
Density 
1.18±0.1 g/cm3(Predicted)
storage temp. 
2-8°C(protect from light)
pka
9.22±0.10(Predicted)
Appearance
White to off-white Solid
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Safety

HS Code 
2933399990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

TRC
Product number
B486215
Product name
4-(Methylsulfonyl)piperidine
Packaging
50mg
Price
$60
Updated
2021/12/16
AK Scientific
Product number
2920AB
Product name
4-(Methylsulfonyl)piperidine
Packaging
250mg
Price
$91
Updated
2021/12/16
Matrix Scientific
Product number
068512
Product name
4-Methylsulfonylpiperidine
Purity
>95%
Packaging
500mg
Price
$93
Updated
2021/12/16
Matrix Scientific
Product number
068512
Product name
4-Methylsulfonylpiperidine
Purity
>95%
Packaging
1g
Price
$143
Updated
2021/12/16
BroadPharm
Product number
BP-11900
Product name
4-(methylsulfonyl)piperidine
Packaging
100mg
Price
$180
Updated
2021/12/16
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4-Methanesulfonyl-piperidine Chemical Properties,Usage,Production

Synthesis

189205-49-0

290328-55-1

General procedure for the synthesis of 4-methylsulfonylpiperidine from tert-butyl 4-(methylsulfonyl)piperidine-1-carboxylate (Step 4): tert-butyl 4-(methylsulfonyl)piperidine-1-carboxylate obtained in Step 3 of Reference Example 12 was dissolved in ethyl acetate (16 mL), followed by the addition of a 4.0 mol/L dioxane solution of hydrogen chloride (12 mL). The reaction mixture was stirred at room temperature for 3 hours. Upon completion of the reaction, the precipitated solid was collected by filtration to afford the target product 4-(methylsulfonyl)piperidine (1.4 g, 76% yield). The structure of the product was confirmed by 1H-NMR (DMSO-d6, 270 MHz) with the following chemical shifts δ (ppm): 3.41-3.31 (m, 3H), 2.97 (s, 3H), 2.97-2.82 (m, 2H), 2.18-2.13 (m, 2H), 1.92-1.73 (m, 2H).

References

[1] Patent: EP1642880, 2006, A1. Location in patent: Page/Page column 112
[2] Patent: US2003/100567, 2003, A1

4-Methanesulfonyl-piperidine Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 4-Methanesulfonyl-piperidine manufacturers

Career Henan Chemical Co
Product
4-Methanesulfonyl-piperidine 290328-55-1
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kg
Release date
2019-12-24