(1R, 2R)-2-Benzylamino-1-cyclohexanol
- Product Name
- (1R, 2R)-2-Benzylamino-1-cyclohexanol
- CAS No.
- 141553-09-5
- Chemical Name
- (1R, 2R)-2-Benzylamino-1-cyclohexanol
- Synonyms
- -2-(Benzylamino);(1R, 2R)-2-Benzylamino-1-cyclohexanol;(1R,2R)-2-(benzylaMino)cyclohexan-1-ol;(1R,2R)-2-BENZYLAMINO-1-CYCLOHEXANOL,MIN.98%;(1R,2R)-2-Benzylamino-1-cyclohexanol,99%e.e.;(1R,2R)-2-Benzylamino-1-cyclohexanol, min. 98%;Cyclohexanol, 2-[(phenylmethyl)amino]-, (1R,2R)-
- CBNumber
- CB41562262
- Molecular Formula
- C13H19NO
- Formula Weight
- 205.3
- MOL File
- 141553-09-5.mol
(1R, 2R)-2-Benzylamino-1-cyclohexanol Property
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- form
- Powder
- color
- white to light-yellow
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 07-0637
- Product name
- (1R,2R)-2-Benzylamino-1-cyclohexanol, min. 98%
- Packaging
- 500mg
- Price
- $64
- Updated
- 2024/03/01
- Product number
- 07-0637
- Product name
- (1R,2R)-2-Benzylamino-1-cyclohexanol, min. 98%
- Packaging
- 2g
- Price
- $194
- Updated
- 2024/03/01
- Product number
- B411220
- Product name
- (1R,2R)-2-(Benzylamino)cyclohexanol
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- P000030949
- Product name
- (1R,2R)-2-(Benzylamino)cyclohexanol
- Purity
- 95+%
- Packaging
- 1g
- Price
- $22
- Updated
- 2021/12/16
- Product number
- P000030949
- Product name
- (1R,2R)-2-(Benzylamino)cyclohexanol
- Purity
- 95+%
- Packaging
- 5g
- Price
- $66
- Updated
- 2021/12/16
(1R, 2R)-2-Benzylamino-1-cyclohexanol Chemical Properties,Usage,Production
Synthesis
286-20-4
100-46-9
40571-86-6
General procedure for the synthesis of trans-2-benzylaminocyclohexanol from cyclohexene oxide and benzylamine: epoxycyclohexane (20 g, 204 mmol) was mixed with benzylamine (44 g, 411 mmol) and the reaction was heated for 6 hours at 80 °C. After completion of the reaction, the excess benzylamine was removed by distillation under reduced pressure. The residue was purified by silica gel column chromatography with the eluent being a chloroform solution of 5-10% methanol to give (1RS,2RS)-trans-2-benzylaminocyclohexanol (26 g, 127 mmol, 62% yield) as white crystals.
References
[1] Tetrahedron Letters, 2008, vol. 49, # 9, p. 1546 - 1550
[2] Tetrahedron, 2011, vol. 67, # 47, p. 9214 - 9218
[3] Journal of Organic Chemistry, 2007, vol. 72, # 10, p. 3713 - 3722
[4] Tetrahedron Letters, 1990, vol. 31, # 32, p. 4661 - 4664
[5] Synthetic Communications, 2001, vol. 31, # 21, p. 3295 - 3302
(1R, 2R)-2-Benzylamino-1-cyclohexanol Preparation Products And Raw materials
Raw materials
Preparation Products
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