4-(4-Methylpiperazin-1-yl)phenylboronic Acid
- Product Name
- 4-(4-Methylpiperazin-1-yl)phenylboronic Acid
- CAS No.
- 229009-40-9
- Chemical Name
- 4-(4-Methylpiperazin-1-yl)phenylboronic Acid
- Synonyms
- 4-(4-Methylpiperazino)benzeneboronic acid;4-(N-Methylpiperazin-1-yl)phenylboronic acid;4-(4-Methylpiperazin-1-yl)phenylboronic Acid;4-(4-Methyl-1-piperazinyl)phenylboronic Acid;4-(4-Methylpiperazin-1-yl)phenylboronic acid 96%;Boronic acid, B-[4-(4-methyl-1-piperazinyl)phenyl]-;[4-(4-methylpiperazin-1-yl)phenyl]boronic acid - [M22502];4-(4-Methyl-1-piperazinyl)phenylboronic Acid（contains varying amounts of Anhydride）
- CBNumber
- CB41564352
- Molecular Formula
- C11H17BN2O2
- Formula Weight
- 220.08
- MOL File
- 229009-40-9.mol
4-(4-Methylpiperazin-1-yl)phenylboronic Acid Property
- Boiling point:
- 406.2±55.0 °C(Predicted)
- Density
- 1.20±0.1 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- pka
- 9.08±0.17(Predicted)
- form
- solid
- color
- White
- InChI
- InChI=1S/C11H17BN2O2/c1-13-6-8-14(9-7-13)11-4-2-10(3-5-11)12(15)16/h2-5,15-16H,6-9H2,1H3
- InChIKey
- LSKYURVDOIDSCG-UHFFFAOYSA-N
- SMILES
- B(C1=CC=C(N2CCN(C)CC2)C=C1)(O)O
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
N-Bromosuccinimide Price
- Product number
- M327495
- Product name
- [4-(4-Methylpiperazin-1-yl)phenyl]boronicAcid
- Packaging
- 5g
- Price
- $565
- Updated
- 2021/12/16
- Product number
- CS-W003780
- Product name
- 4-(4-Methylpiperazin-1-yl)phenylboronicacid
- Purity
- 99.81%
- Packaging
- 1g
- Price
- $64
- Updated
- 2021/12/16
- Product number
- M22502
- Product name
- [4-(4-methylpiperazin-1-yl)phenyl]boronicacid
- Purity
- 97.0%
- Packaging
- 1g
- Price
- $100
- Updated
- 2021/12/16
- Product number
- 8H60-1-HG
- Product name
- 4-(4-Methylpiperazin-1-yl)phenylboronic acid
- Packaging
- 1g
- Price
- $152
- Updated
- 2021/12/16
- Product number
- BOR0006778
- Product name
- 4-(4-METHYLPIPERAZIN-1-YL)PHENYLBORONIC ACID
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $197.4
- Updated
- 2021/12/16
4-(4-Methylpiperazin-1-yl)phenylboronic Acid Chemical Properties,Usage,Production
Uses
[4-(4-Methylpiperazin-1-yl)phenyl]boronic Acid is a useful synthetic compound.
Synthesis
5419-55-6
130307-08-3
229009-40-9
(ii) Preparation of 53c: 4-(4-methylpiperazin-1-yl)phenylboronic acid To a solution of 53b (390 mg, 1.52 mmol) and THF (10 mL), n-butyllithium (0.79 mL, 2.5 M hexane solution) was slowly added at -78 °C and stirred for 10 min. Subsequently, triisopropyl borate (1.75 mL, 7.64 mmol) was added at the same temperature. The reaction mixture was slowly warmed to room temperature and then the reaction was quenched with phosphoric acid. The reaction mixture was neutralized with saturated NaHCO3 solution and subsequently extracted with EtOAc (3 x 10 mL). The organic phases were combined, dried with anhydrous Na2SO4, filtered and concentrated under reduced pressure. The residue was purified by column chromatography (silica gel, 0-10% MeOH in CH2Cl2 solution) to afford the target product 4-(4-methyl-1-piperazinyl)phenylboronic acid (180 mg, 58%). 1H NMR (300 MHz, CD3OD) δ 2.32 (s, 3H), 2.55 (m, 4H), 3.03 (s, 1H), 3.21 (m, 3H), 6.69-7.59 (m, 4H).
References
[1] Patent: US8324264, 2012, B1. Location in patent: Page/Page column 181
[2] Patent: EP2712863, 2014, A1. Location in patent: Paragraph 0435; 0436
4-(4-Methylpiperazin-1-yl)phenylboronic Acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-(4-Methylpiperazin-1-yl)phenylboronic Acid manufacturers
- Product
- 4-(4-Methylpiperazin-1-yl)phenylboronic Acid 229009-40-9
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- 4-(4-Methylpiperazin-1-yl)phenylboronic Acid 229009-40-9
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09
- Product
- 4-(4-Methylpiperazin-1-yl)phenylboronic Acid 229009-40-9
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- JD 810
- Release date
- 2019-09-02