ChemicalBook > CAS DataBase List > STE-MPKKKPTPIQLNP-NH2
STE-MPKKKPTPIQLNP-NH2
- Product Name
- STE-MPKKKPTPIQLNP-NH2
- CAS No.
- 566872-15-9
- Chemical Name
- STE-MPKKKPTPIQLNP-NH2
- Synonyms
- STE-MEK1(13);STE-MPKKKPTPIQLNP-NH2;STEARYL-MEK-1 DERIVED PEPTIDE INHIBITOR 1, AMIDE;ERK ACTIVATION INHIBITOR PEPTIDE I, CELL-PERMEABLE;STE-MET-PRO-LYS-LYS-LYS-PRO-THR-PRO-ILE-GLN-LEU-ASN-PRO-NH2;L-Prolinamide, N-(1-oxooctadecyl)-L-methionyl-L-prolyl-L-lysyl-L-lysyl-L-lysyl-L-prolyl-L-threonyl-L-prolyl-L-isoleucyl-L-glutaminyl-L-leucyl-L-asparaginyl-
- CBNumber
- CB4159696
- Molecular Formula
- C86H153N19O17S
- Formula Weight
- 1757.32
- MOL File
- Mol file
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STE-MPKKKPTPIQLNP-NH2 Property
- Boiling point:
- 1814.130±65.00 °C(Press: 760.00 Torr)(predicted)
- Density
- 1.196±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
- storage temp.
- -20°C
- solubility
- water: 1 mg/mL || DMSO: 5 mg/mL
- form
- lyophilized solid
- pka
- 13.329±0.46(predicted)
- color
- white
- Water Solubility
- water: 1mg/mL
DMSO: 5mg/mL - Sequence
- {Ste}-Met-Pro-Lys-Lys-Lys-Pro-Thr-Pro-Ile-Gln-Leu-Asn-Pro-NH2
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Safety
- WGK Germany
- WGK 1
- Storage Class
- 11 - Combustible Solids
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 328000
- Product name
- ERK Activation Inhibitor Peptide I, Cell-Permeable
- Purity
- The ERK Activation Inhibitor Peptide I, Cell-Permeable controls the biological activity of ERK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation application
- Packaging
- 1 mg
- Price
- $214
- Updated
- 2025/07/31
American Custom Chemicals Corporation
- Product number
- PEP0003409
- Product name
- STEARYL - MEK - 1 DERIVED PEPTIDE INHIBITOR 1, AMIDE
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $685.21
- Updated
- 2021/12/16
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STE-MPKKKPTPIQLNP-NH2 Chemical Properties,Usage,Production
Uses
STE-MEK1(13) (Ste-MPKKKPTPIQLNP-NH ) is a cell permeable ERK1/2 inhibitor (IC50: 13-30 μM). STE-MEK1(13) inhibits ERK1/2 phosphorylation[1][2].
Biological Activity
Cell permeable: yes', 'Primary Target
MEK', 'Product does not compete with ATP.', 'Reversible: yes
References
[1] Li G, et al. A novel cellular survival factor--the B2 subunit of vacuolar H+-ATPase inhibits apoptosis. Cell Death Differ. 2006 Dec;13(12):2109-17. DOI:10.1038/sj.cdd.4401970
[2] Whiteman M, et al. Peroxynitrite-modified collagen-II induces p38/ERK and NF-kappaB-dependent synthesis of prostaglandin E2 and nitric oxide in chondrogenically differentiated mesenchymal progenitor cells. Osteoarthritis Cartilage. 2006 May;14(5):460-70. DOI:10.1016/j.joca.2005.11.002
STE-MPKKKPTPIQLNP-NH2 Preparation Products And Raw materials
Raw materials
Preparation Products
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