1-(2-methoxyethyl)-1H-pyrazol-4-amine

Product Name: 1-(2-methoxyethyl)-1H-pyrazol-4-amine
CAS No.: 948570-74-9
Chemical Name: 1-(2-methoxyethyl)-1H-pyrazol-4-amine
Synonyms: 1-(2-Methoxyethyl)pyrazol-4-amine;1-(2-methoxyethyl)-1H-pyrazol-4-amine;4-Amino-1-(2-methoxyethyl)-1H-pyrazole;1-(2-Methoxyethyl)-1H-pyrazol-4-ylamine;1H-Pyrazol-4-amine, 1-(2-methoxyethyl)-
CBNumber: CB41610196
Molecular Formula: C6H11N3O
Formula Weight: 141.17
MOL File: 948570-74-9.mol

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1-(2-methoxyethyl)-1H-pyrazol-4-amine Property

Boiling point:: 277.0±20.0 °C(Predicted)
Density: 1.19±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 3.48±0.10(Predicted)
form: liquid
color: Light brown to brown

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Safety

HS Code: 2922390090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: M139290
Product name: 1-(2-methoxyethyl)-1H-pyrazol-4-amine
Packaging: 250mg
Price: $350
Updated: 2021/12/16

Matrix Scientific

Product number: 101774
Product name: 1-(2-Methoxyethyl)-1H-pyrazol-4-amine
Purity: 95%
Packaging: 250mg
Price: $262
Updated: 2021/12/16

Matrix Scientific

Product number: 101774
Product name: 1-(2-Methoxyethyl)-1H-pyrazol-4-amine
Purity: 95%
Packaging: 500mg
Price: $418
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H30-1-8H
Product name: 1-(2-Methoxyethyl)-1H-pyrazol-4-amine
Packaging: 1g
Price: $495
Updated: 2021/12/16

Matrix Scientific

Product number: 101774
Product name: 1-(2-Methoxyethyl)-1H-pyrazol-4-amine
Purity: 95%
Packaging: 1g
Price: $670
Updated: 2021/12/16

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1-(2-methoxyethyl)-1H-pyrazol-4-amine Chemical Properties,Usage,Production

Synthesis

948570-75-0

948570-74-9

General procedure: A solution of 1-(2-methoxyethyl)-4-nitro-1H-pyrazole (2.5 g, 14.60 mmol) in ethanol (250 mL) was added to a standard flask, followed by palladium carbon (20% w/w, 0.50 g). The flask was evacuated and replaced with hydrogen. The reaction was stirred under hydrogen atmosphere (1 atm) for 16 hours. After completion of the reaction, the reaction solution was filtered through a sintered funnel with a diatomaceous earth pad and the filter cake was washed with methanol. The filtrate was concentrated under reduced pressure to afford 1-(2-methoxyethyl)-1H-pyrazol-4-amine (2.0 g, 97% yield), which was used directly in the next reaction without further purification.1H NMR (400 MHz, CDCl3): δ 7.03 (s, 1H), 6.89 (s, 1H), 4.19-4.17 (t, 2H), 3.78 ( br s, 2H), 3.67-3.64 (t, 2H), 3.21 (s, 3H). Mass spectrum (MS): 142.11 (M + H).

References

[1] Patent: WO2015/25197, 2015, A1. Location in patent: Paragraph 00079
[2] Patent: US2015/336982, 2015, A1. Location in patent: Paragraph 0436; 0438
[3] Patent: CN104583195, 2018, B. Location in patent: Paragraph 0633; 0634; 0638; 0639; 0640
[4] Patent: WO2007/99326, 2007, A1. Location in patent: Page/Page column 104
[5] Patent: WO2015/48281, 2015, A1. Location in patent: Paragraph 00426; 00428

1-(2-methoxyethyl)-1H-pyrazol-4-amine Preparation Products And Raw materials

Raw materials

Preparation Products

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1-(2-methoxyethyl)-1H-pyrazol-4-amine Suppliers

China 58 India 2 Ukraine 1 United Kingdom 1 United States 5 Global 67

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948570-74-9, 1-(2-methoxyethyl)-1H-pyrazol-4-amineRelated Search:

1-(2-methoxyethyl)-1H-pyrazol-4-amine

1-(2-Methoxyethyl)pyrazol-4-amine

4-Amino-1-(2-methoxyethyl)-1H-pyrazole

1H-Pyrazol-4-amine, 1-(2-methoxyethyl)-

1-(2-Methoxyethyl)-1H-pyrazol-4-ylamine

948570-74-9