2-(3-Chloro-phenyl)-pyrrolidine
- Product Name
- 2-(3-Chloro-phenyl)-pyrrolidine
- CAS No.
- 298690-74-1
- Chemical Name
- 2-(3-Chloro-phenyl)-pyrrolidine
- Synonyms
- AKOS BB-8867;CHEMBRDG-BB 4006410;2-(3-CHLOROPHENYL)PYRROLIDINE;Pyrrolidine, 2-(3-chlorophenyl)-;(+/-)-2-(3-chlorophenyl)-pyrrolidine
- CBNumber
- CB4175836
- Molecular Formula
- C10H12ClN
- Formula Weight
- 181.66
- MOL File
- 298690-74-1.mol
2-(3-Chloro-phenyl)-pyrrolidine Property
- Boiling point:
- 138-141 °C(Press: 16 Torr)
- Density
- 1.129±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C(protect from light)
- pka
- 9.58±0.10(Predicted)
- CAS DataBase Reference
- 298690-74-1(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H314Causes severe skin burns and eye damage
H361Suspected of damaging fertility or the unborn child
H410Very toxic to aquatic life with long lasting effects
- Precautionary statements
-
P201Obtain special instructions before use.
P202Do not handle until all safety precautions have been read and understood.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P308+P313IF exposed or concerned: Get medical advice/attention.
P363Wash contaminated clothing before reuse.
P391Collect spillage. Hazardous to the aquatic environment
P405Store locked up.
N-Bromosuccinimide Price
- Product number
- C350775
- Product name
- 2-(3-Chlorophenyl)pyrrolidine
- Packaging
- 100mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- OR962418
- Product name
- 2-(3-Chlorophenyl)pyrrolidine
- Purity
- 97%
- Packaging
- 5g
- Price
- $345
- Updated
- 2021/12/16
- Product number
- OR962418
- Product name
- 2-(3-Chlorophenyl)pyrrolidine
- Purity
- 97%
- Packaging
- 1g
- Price
- $115
- Updated
- 2021/12/16
- Product number
- 3067AB
- Product name
- 2-(3-Chlorophenyl)pyrrolidine
- Packaging
- 1g
- Price
- $246
- Updated
- 2021/12/16
- Product number
- FC50791
- Product name
- 2-(3-Chlorophenyl)pyrrolidine
- Packaging
- 1g
- Price
- $260.6
- Updated
- 2021/12/16
2-(3-Chloro-phenyl)-pyrrolidine Chemical Properties,Usage,Production
Uses
Used as an intermediate for organic synthesis.
Application
(+/-)-2-(3-chlorophenyl)-pyrrolidine has a wide application in synthesis of pharma intermediates，It is also used as an antioxidant.
Reactions
2-(3-Chloro-phenyl)-pyrrolidine is an important building block for the synthesis of various organic compounds. Through the coupling of the amine, It could be employed to couple with 4-(4-formylphenoxy)-1-naphthamide to synthesize 4-[4-[2-(3-Chlorophenyl)pyrrolidin-1-yl]methylphenoxyl]-1-naphthamide which is an aminobenzyloxyarylamide derivatives and act as κ opioid receptor antagonists.
Synthesis
To a solution of substituted benzoic acid inabsolute ethyl alcohol was slowly added thionyl chloride. The mixture was heated to reflux for 2h, and then cooledto room temperature. The solvent was removed and the solid residuewas dissolved in ethyl acetate, and washed withsaturated NaHCO3 solution. After a series of reactions, 3-(2-chloro-phenyl)-pyrrolidine can be obtained.
2-(3-Chloro-phenyl)-pyrrolidine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-(3-Chloro-phenyl)-pyrrolidine manufacturers
- Product
- 3-(2-CHLORO-PHENYL)-PYRROLIDINE 298690-74-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2019-12-23