IRISQUINONE

Product Name: IRISQUINONE
CAS No.: 56495-82-0
Chemical Name: IRISQUINONE
Synonyms: pallasone;Irisquinone A;IRISQUINONE;IRISQUINONE USP/EP/BP;2-(10-heptadecenyl)-6-methoxy-5-cyclohexadiene-(z)-4-dione;2-(10-heptadecenyl)-6-methoxy-5-cyclohexadiene- (z)-4-dione;6-methoxy-2-delta(sup 10')-cis-heptadecenyl-1,4-benzoquinone;Irisquinone A,2-(cis-10-Heptadecenyl)-6-methoxy-p-benzoquinone;2-[(Z)-10-Heptadecenyl]-6-methoxy-2,5-cyclohexadiene-1,4-dione;2-[(Z)-heptadec-10-enyl]-6-methoxycyclohexa-2,5-diene-1,4-dione
CBNumber: CB4184933
Molecular Formula: C24H38O3
Formula Weight: 374.56
MOL File: 56495-82-0.mol

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IRISQUINONE Property

Melting point:: 40-43 °C
Boiling point:: 483.4±34.0 °C(Predicted)
Density: 0.97±0.1 g/cm3(Predicted)
LogP: 8.850 (est)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: API0012937
Product name: IRISQUINONE
Purity: 98.00%
Packaging: 5MG
Price: $504.93
Updated: 2021/12/16

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IRISQUINONE Chemical Properties,Usage,Production

Uses

Irisquinone, a natural product, is an anticancer agent. Irisquinone is also a radiation sensitizer for cancer. Irisquinone reduces GSH level and inhibits the repair of DNA singular strand breaks[1][2][3].

in vivo

Irisquinone (12.5 mg/kg, perfused daily) makes the rabbit VX2 lung transplant tumor wall thinner and the necrotic area larger in the irisquinone + radiotherapy group^[1].

Animal Model:	Rabbit bearing VX2 lung transplant tumor^[1]
Dosage:	12.5 mg/kg
Administration:	Perfused daily, starting from 3 days before irradiation to the end of irradiation.
Result:	Displayed no significant difference of tumor growth between the radio therapy and Irisquinone + radiotherapy groups. Showed thinner tumor wall and the larger necrotic area in the Irisquinone + radiotherapy group.

References

[1] Xu H, et al. Dynamic observation of the radiosensitive effect of irisquinone on rabbit VX2 lung transplant tumors by using fluorine-18-deoxyglucose positron emission tomography/computed tomography. Nucl Med Commun. 2013 Mar;34(3):220-8. DOI:10.1097/MNM.0b013e32835d3730
[2] Wang H, et al. Radiosensitizing effect of irisquinone on glioma through the downregulation of HIF-1α evaluated by 18F-FDG and 18F-FMISO PET/CT. Nucl Med Commun. 2016 Jul;37(7):705-14. DOI:10.1097/MNM.0000000000000498
[3] Liang, l., et al. The effect of Irisquinone on the glutathione system and MRP expression of cisplatin-resistant human lung adenocarcinoma cell line (A DDP549). Chin J Cancer Res 13, 171–175 (2001).

IRISQUINONE Preparation Products And Raw materials

Raw materials

Preparation Products

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IRISQUINONE Suppliers

China 28 United States 4 USA 1 Global 33

Shanghai Winherb Medical Technology Co., Ltd.

Tel: 021-38218169 13341702378
Fax: QQ：190129269
Email: winherb@126.com
Country: China
ProdList: 1245
Advantage: 58

Suzhou yacoo science co.,Ltd

Tel: 0512-87182056 18013166090
Fax: 0512-87182056
Email: lingling.qi@yacoo.com.cn
Country: China
ProdList: 6295
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Raw material medicin reagent co.,Ltd

Tel
Email: sales@njromanme.com
Country: China
ProdList: 4529
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Chengdu Push Bio-Technology Co., Ltd.

Tel: 028-028-85370565-229-229 18080489829
Email: 18080489829@163.com
Country: China
ProdList: 8250
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Dideu Industries Group Limited

Tel: +86-29-89586680 +86-15129568250
Email: 1026@dideu.com
Country: China
ProdList: 20284
Advantage: 58

AFINE CHEMICALS LIMITED

Tel: +86-0571-85134551
Fax: 008657185134895
Email: sales@afinechem.com
Country: China
ProdList: 15109
Advantage: 58

SIMAGCHEM CORP

Tel: +86-5922680277 +86-13806087780
Email: sale@simagchem.com
Country: China
ProdList: 17346
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Hubei xin bonus chemical co. LTD

Tel: 86-13657291602
Fax: 027-59338440
Email: linda@hubeijusheng.com
Country: CHINA
ProdList: 22963
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Wuhan Yanzhe Technology Co., Ltd

Tel: 15527250409
Fax: QQ：2692360204
Email: wenhaotian12@163.com
Country: China
ProdList: 4171
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Wuhan Topule

Tel: +86-02787215551 +86-19945035818
Fax: 027-87215551
Email: 2936752263@qq.com
Country: China
ProdList: 7986
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View Lastest Price from IRISQUINONE manufacturers

Dideu Industries Group Limited

Product: IRISQUINONE 56495-82-0
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons Min
Release date: 2021-07-05

Shaanxi Dideu Medichem Co. Ltd

Product: Irisquinone 56495-82-0
Price: US $0.00-0.00/Kg
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 800 ton
Release date: 2020-04-30

56495-82-0, IRISQUINONERelated Search:

Lenvatinib Formestane Cisapride CalciuM polycarbophil Ibandronic acid β-Cyclodextrin Sorafenib tosylate Nattokinase Hematoprophyrin IRISQUINONE B PALLASONE C IRISQUINONE PRIMIN (E,Z)-2,13-OCTADECADIENAL

2-(10-heptadecenyl)-6-methoxy-5-cyclohexadiene- (z)-4-dione

2-(10-heptadecenyl)-6-methoxy-5-cyclohexadiene-(z)-4-dione

6-methoxy-2-delta(sup 10')-cis-heptadecenyl-1,4-benzoquinone

pallasone

2-[(Z)-10-Heptadecenyl]-6-methoxy-2,5-cyclohexadiene-1,4-dione

Irisquinone A

IRISQUINONE

2,5-Cyclohexadiene-1,4-dione, 2-(10Z)-10-heptadecen-1-yl-6-methoxy-

2-[(Z)-heptadec-10-enyl]-6-methoxycyclohexa-2,5-diene-1,4-dione

IRISQUINONE USP/EP/BP

Irisquinone A,2-(cis-10-Heptadecenyl)-6-methoxy-p-benzoquinone

56495-82-0