4-bromo-2,6-dimethylbenzoic acid
- Product Name
- 4-bromo-2,6-dimethylbenzoic acid
- CAS No.
- 74346-19-3
- Chemical Name
- 4-bromo-2,6-dimethylbenzoic acid
- Synonyms
- 4-bromo-2,6-dimethylbenzoic acid;2, 6-dimethyl-4-bromobenzoic acid;Benzoic acid, 4-broMo-2,6-diMethyl-
- CBNumber
- CB41884825
- Molecular Formula
- C9H9BrO2
- Formula Weight
- 229.07
- MOL File
- 74346-19-3.mol
4-bromo-2,6-dimethylbenzoic acid Property
- Melting point:
- 197-198 °C
- Boiling point:
- 321.1±30.0 °C(Predicted)
- Density
- 1.520±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- form
- solid
- pka
- 3.29±0.37(Predicted)
- color
- Yellow
Safety
- HS Code
- 2916399090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B691573
- Product name
- 4-Bromo-2,6-dimethylbenzoicacid
- Packaging
- 250mg
- Price
- $95
- Updated
- 2021/12/16
- Product number
- OR907248
- Product name
- 4-Bromo-2,6-dimethylbenzoicacid
- Packaging
- 1g
- Price
- $87
- Updated
- 2021/12/16
- Product number
- FB144065
- Product name
- 4-Bromo-2,6-dimethylbenzoic acid
- Packaging
- 500mg
- Price
- $90
- Updated
- 2021/12/16
- Product number
- W8208
- Product name
- 4-Bromo-2,6-dimethylbenzoicacid
- Packaging
- 10g
- Price
- $384
- Updated
- 2021/12/16
- Product number
- FB144065
- Product name
- 4-Bromo-2,6-dimethylbenzoic acid
- Packaging
- 5G
- Price
- $400
- Updated
- 2021/12/16
4-bromo-2,6-dimethylbenzoic acid Chemical Properties,Usage,Production
Chemical Properties
off-white powder
Synthesis
124-38-9
206559-43-5
74346-19-3
Example 2: Preparation of 4-bromo-2,6-dimethylbenzoic acid (B2) The title compound can be prepared according to Scheme B as follows. 5-Bromo-2-iodo-1,3-dimethylbenzene (B1) (1.0 mole equivalent) was dissolved in methyl tert-butyl ether (6.0 relative volume), and this solution was slowly added to a solution of isopropylmagnesium chloride (2.0 mole equivalents) in methyl tert-butyl ether (2.0 relative volume) that had been pre-cooled to < 0 °C. Carbon dioxide gas was passed through until the reaction was complete while maintaining low temperature conditions. Upon completion of the reaction, 2N aqueous hydrochloric acid (4 relative volume) was added to quench the reaction, the organic and aqueous phases were separated and the aqueous phase was discarded. The organic phase was extracted with 1M aqueous sodium hydroxide solution (6.5 relative volume) and subsequently washed with methyl tert-butyl ether (4 relative volume). The aqueous phase was acidified by addition of 2N aqueous hydrochloric acid (4.5 relative volume) to precipitate the title compound (B2). The precipitate was collected by filtration, washed sequentially with water and heptane and dried to give a white crystalline solid in 85% yield. 1H NMR (400 MHz, CDCl3) δH 2.28 (6H, s), 7.35 (2H, s), 13.30 (1H, s).
References
[1] Patent: WO2011/84098, 2011, A1. Location in patent: Page/Page column 6-7
[2] Organic Process Research and Development, 2012, vol. 16, # 5, p. 741 - 747
4-bromo-2,6-dimethylbenzoic acid Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-bromo-2,6-dimethylbenzoic acid manufacturers
- Product
- 74346-19-3 74346-19-3
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 200kg
- Release date
- 2018-12-25