Description References
ChemicalBook > CAS DataBase List > 2-Methoxypyrazine

2-Methoxypyrazine

Description References
Product Name
2-Methoxypyrazine
CAS No.
3149-28-8
Chemical Name
2-Methoxypyrazine
Synonyms
METHOXYPYRAZINE;Pyrazine, methoxy-;FEMA 3302;methoxy-pyrazin;FEMA NUMBER 3302;2-METHOXYPYRAZINE;Methoxypyrazine,98%;METHOXYPYRAZINE, 2-;Pyrazine, 2-Methoxy-;2-Methoxypyrazine>
CBNumber
CB4202646
Molecular Formula
C5H6N2O
Formula Weight
110.11
MOL File
3149-28-8.mol
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2-Methoxypyrazine Property

Boiling point:
60-61 °C/29 mmHg (lit.)
Density 
1.14 g/mL at 25 °C (lit.)
refractive index 
n20/D 1.509(lit.)
FEMA 
3302 | METHOXYPYRAZINE
Flash point:
114 °F
storage temp. 
Sealed in dry,Room Temperature
pka
0.53±0.10(Predicted)
form 
clear liquid
color 
Colorless to Almost colorless
Specific Gravity
1.140
Odor
at 1.00 % in dipropylene glycol. sweet nutty cocoa
Odor Type
chocolate
JECFA Number
787
BRN 
2241
LogP
0.75
CAS DataBase Reference
3149-28-8(CAS DataBase Reference)
NIST Chemistry Reference
Pyrazine, methoxy-(3149-28-8)
EPA Substance Registry System
Pyrazine, methoxy- (3149-28-8)
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Safety

Hazard Codes 
Xn
Risk Statements 
10-22-37/38-41
Safety Statements 
16-26-39
RIDADR 
UN 1993 3/PG 3
WGK Germany 
3
TSCA 
Yes
HazardClass 
3
PackingGroup 
III
HS Code 
29339990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H226Flammable liquid and vapour

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
W330205
Product name
2-Methoxypyrazine
Purity
≥99%, FCC, FG
Packaging
1kg
Price
$1120
Updated
2023/01/07
Sigma-Aldrich
Product number
291420
Product name
2-Methoxypyrazine
Purity
95%
Packaging
5g
Price
$33
Updated
2023/01/07
Sigma-Aldrich
Product number
W330205
Product name
2-Methoxypyrazine
Purity
≥99%, FCC, FG
Packaging
sample-k
Price
$53.8
Updated
2022/05/15
Sigma-Aldrich
Product number
W330205
Product name
2-Methoxypyrazine
Purity
≥99%, FCC, FG
Packaging
25g
Price
$102
Updated
2022/05/15
Sigma-Aldrich
Product number
W330205
Product name
2-Methoxypyrazine
Purity
≥99%, FCC, FG
Packaging
100g
Price
$166
Updated
2022/05/15
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2-Methoxypyrazine Chemical Properties,Usage,Production

Description

2-methoxypyrazine is a kind of pyrazine derivative. It emits a kernels and cocoa-like aroma. It is a commonly used daily, food flavoring agent. It has many kinds of flavoring derivatives such as 3-Isobutyl-2-methoxypyrazine, 3-sec-butyl-2-methoxypyrazine, 3-alkyl-2-methoxypyrazines and 3-isopropyl-2-methoxypyrazine. There derivatives could be found in wine and many kinds of fruits such as berry and grapes.

References

Murray, K. E., J. Shipton, and F. B. Whitfield. "2-methoxypyrazines and the flavour of green peas (Pisum sativum). " Chemistry & Industry 27.14(1970):897-898.
Hashizume, Katsumi, and Takashi Samuta. "Grape maturity and light exposure affect berry methoxypyrazine concentration." American Journal of Enology and Viticulture 50.2 (1999): 194-198.
Hartmann, Peter J., Harold M. McNair, and Bruce W. Zoecklein. "Measurement of 3-alkyl-2-methoxypyrazine by headspace solid-phase microextraction in spiked model wines." American Journal of Enology and Viticulture 53.4 (2002): 285-288.
HASHiZUME, Katsumi, and Norihiko Umeda. "Methoxypyrazine content of Japanese red wines." Bioscience, biotechnology, and biochemistry 60.5 (1996): 802-805.
Lacey, Michael J., et al. "Methoxypyrazines in Sauvignon blanc grapes and wines." American Journal of Enology and Viticulture 42.2 (1991): 103-108.

Description

Methoxypyrazine has an odor threshold of 700 ppb in water. Methoxypyrazine may be prepared from 2-hydroxypyrazine by various routes.

Chemical Properties

Methoxypyrazine has a sweet, nutty, cocoa odor. Methoxypyrazine contributes a distinctive “green, capsicum (bell pepper), herbaceous and earthy” aroma that is quite characteristic of certain wines, such as sauvignon blanc and cabernet sauvignon.

Chemical Properties

Colorless liquid

Occurrence

Present at ultra-trace levels in sauvignon blanc and cabernet sauvignon grapes and wine. Methoxypyrazine contributes a distinctive wine aroma, even at low parts per trillion levels. Also reported found in cooked beef, cocoa, malt and krill.

Definition

ChEBI: Methoxypyrazine is an aromatic ether and a member of pyrazines.

Preparation

From 2-hydroxypyrazine by various routes.

Aroma threshold values

700 ppb in water

Safety Profile

Skin and eye irritant. When heated to decomposition it emits toxic fumes of NOx.

2-Methoxypyrazine Preparation Products And Raw materials

Raw materials

2-HYDROXYPYRAZINE Sodium Methoxide

Preparation Products

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2-Methoxypyrazine Suppliers

Americas 1 Belgium 1 China 187 Europe 1 France 2 Germany 7 India 5 Japan 3 Norway 1 Slovakia 1 Switzerland 1 The Netherlands 1 United Kingdom 13 United States 63 USA 1 Global 288
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View Lastest Price from 2-Methoxypyrazine manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd
Product
2-Methoxypyrazine 3149-28-8
Price
US $50.00/kg
Min. Order
1kg
Purity
99
Supply Ability
5000
Release date
2024-12-06
Hebei Weibang Biotechnology Co., Ltd
Product
2-Methoxypyrazine 3149-28-8
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-07
Hebei Chuanghai Biotechnology Co,.LTD
Product
2-Methoxypyrazine 3149-28-8
Price
US $5.00-2.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10000kg
Release date
2024-08-23

3149-28-8, 2-MethoxypyrazineRelated Search:

Sulfachoropyrazine sodium Tetramethylpyrazine 2-Methylpyrazine Pyrazinamide Glipizide 2-Methoxy-3-isobutyl pyrazine 2-Isopropyl-5-methoxypyrazine,2-Isopropyl-6-methoxypyrazine,2-Isopropyl-3-methoxypyrazine 2-METHYL-6-PROPOXYPYRAZINE 2-ETHYL-3-METHOXYPYRAZINE 99+% butylmethoxypyrazine,2-sec-butyl-3-methoxypyrazine,2-methoxy-3-(sec-butyl)-pyrazine,3-S-BUTYL-2-METHOXYPYRAZINE,2-SEC-BUTYL-3-METHOXYPYRAZINE 99% 2-Ethoxypyrazine 3-Methyl-2-methoxypyrazine 2-ETHOXY-3-METHYLPYRAZINE 2-Isopropyl-3-methoxypyrazine 2-AMINO-5-METHOXYPYRAZINE 2-BROMO-5-METHOXYPYRAZINE 2,3-Dimethoxyquinoxaline 2-ETHOXY-3-ISOPROPYLPYRAZINE

  • METHOXYPYRAZINE
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  • FEMA 3302
  • FEMA NUMBER 3302
  • methoxy-pyrazin
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  • 2-Methoxypyrazine USP/EP/BP
  • 3149-28-8 2-Methoxypyrazine
  • 3149-28-8
  • C5H6N20
  • Pyrazines
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  • Heterocyclic Building Blocks
  • Alkoxypyrazines
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