1-methyl-1H-imidazol-2-amine
- Product Name
- 1-methyl-1H-imidazol-2-amine
- CAS No.
- 6646-51-1
- Chemical Name
- 1-methyl-1H-imidazol-2-amine
- Synonyms
- CAS:6646-51-1;1-methylimidazol-2-amine;2-Amino-1-methylimidazole;1-Methyl-2-aminoimidazole;1-methyl-1H-imidazol-2-amine;1H-IMidazol-2-aMine,1-Methyl-;1-Methyl-1H-imidazol-2-ylamine;2-AMino-1-Methyl-1H-iMidazole, 97%;1-methyl-1H-imidazol-2-amine(SALTDATA: HCl)
- CBNumber
- CB42069382
- Molecular Formula
- C4H7N3
- Formula Weight
- 97.12
- MOL File
- 6646-51-1.mol
1-methyl-1H-imidazol-2-amine Property
- Boiling point:
- 255℃
- Density
- 1.22
- Flash point:
- 108℃
- storage temp.
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- pka
- 8.53±0.25(Predicted)
- form
- solid
- color
- White
- InChI
- InChI=1S/C4H7N3/c1-7-3-2-6-4(7)5/h2-3H,1H3,(H2,5,6)
- InChIKey
- NQCJWEXYVVFKBT-UHFFFAOYSA-N
- SMILES
- C1(N)N(C)C=CN=1
Safety
- HS Code
- 2933299090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- M312960
- Product name
- 1-Methyl-1H-imidazol-2-amine
- Packaging
- 100mg
- Price
- $160
- Updated
- 2021/12/16
- Product number
- M312960
- Product name
- 1-Methyl-1H-imidazol-2-amine
- Packaging
- 1g
- Price
- $1260
- Updated
- 2021/12/16
- Product number
- CS-W004745
- Product name
- 1-Methyl-1H-imidazol-2-amine
- Purity
- 99.61%
- Packaging
- 10g
- Price
- $750
- Updated
- 2021/12/16
- Product number
- 119142
- Product name
- 1-Methyl-1H-imidazol-2-amine
- Purity
- 95+%
- Packaging
- 5g
- Price
- $965
- Updated
- 2021/12/16
- Product number
- 47497
- Product name
- 1-Methyl-1H-imidazol-2-amine
- Packaging
- 1g
- Price
- $2200
- Updated
- 2021/12/16
1-methyl-1H-imidazol-2-amine Chemical Properties,Usage,Production
Uses
1-Methyl-1H-imidazol-2-amine, is an intermediate in the synthesis of variety of antibacterial and antitumor agents.
Synthesis
1671-82-5
6646-51-1
General procedure for the synthesis of 2-amino-1-methylimidazole from 1-methyl-2-nitro-1H-imidazole: To a stirred solution of 1-methyl-2-nitro-1H-imidazole (500 mg, 3.9 mmol) in acetic acid (15 mL) was added iron powder (1.34 g, 24 mmol). The reaction mixture was stirred at 80 °C overnight. Upon completion of the reaction, the mixture was filtered through a diatomaceous earth pad and the filtrate was concentrated under vacuum. The residue was purified by preparative high performance liquid chromatography (HPLC) using a C18 column with an elution gradient of 10% to 90% acetonitrile/water (containing 0.1% formic acid) solution to afford 2-amino-1-methylimidazole (66 mg, 17% yield) as a yellow solid.
References
[1] Patent: WO2016/4272, 2016, A1. Location in patent: Paragraph 00799
1-methyl-1H-imidazol-2-amine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1-methyl-1H-imidazol-2-amine manufacturers
- Product
- 2-Amino-1-methylimidazole 6646-51-1
- Price
- US $0.00-0.00/kg
- Min. Order
- 0.0001kg
- Purity
- 98%min
- Supply Ability
- 100kgs/month
- Release date
- 2022-05-10
- Product
- 1-methyl-1H-imidazol-2-amine 6646-51-1
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- >10kg
- Release date
- 2021-07-15
- Product
- 1-methyl-1H-imidazol-2-amine 6646-51-1
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2020-01-02