2-HYDROXY-4-METHYL-BENZONITRILE
- Product Name
- 2-HYDROXY-4-METHYL-BENZONITRILE
- CAS No.
- 18495-14-2
- Chemical Name
- 2-HYDROXY-4-METHYL-BENZONITRILE
- Synonyms
- 2-Hydroxy-4-methyk-benzonitrile;2-HYDROXY-4-METHYL-BENZONITRILE;Benzonitrile, 2-hydroxy-4-Methyl-
- CBNumber
- CB4208996
- Molecular Formula
- C8H7NO
- Formula Weight
- 133.15
- MOL File
- 18495-14-2.mol
2-HYDROXY-4-METHYL-BENZONITRILE Property
- Melting point:
- 87 °C
- Boiling point:
- 286.0±28.0 °C(Predicted)
- Density
- 1.17±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 7.28±0.10(Predicted)
- Appearance
- Light brown to yellow Solid
Safety
- HS Code
- 2926907090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- H633090
- Product name
- 2-Hydroxy-4-methylbenzonitrile
- Packaging
- 250mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- W3997
- Product name
- 2-Hydroxy-4-methyl-benzonitrile
- Packaging
- 5g
- Price
- $171
- Updated
- 2021/12/16
- Product number
- OR903861
- Product name
- 2-Hydroxy-4-methylbenzonitrile
- Purity
- 98%
- Packaging
- 5g
- Price
- $218
- Updated
- 2021/12/16
- Product number
- W3997
- Product name
- 2-Hydroxy-4-methyl-benzonitrile
- Packaging
- 10g
- Price
- $237
- Updated
- 2021/12/16
- Product number
- OR903861
- Product name
- 2-Hydroxy-4-methylbenzonitrile
- Purity
- 98%
- Packaging
- 10g
- Price
- $377
- Updated
- 2021/12/16
2-HYDROXY-4-METHYL-BENZONITRILE Chemical Properties,Usage,Production
Synthesis
84159-60-4
18495-14-2
2-Hydroxy-4-methylbenzaldehyde oxime (23 g) was added to 190 mL of acetic anhydride. The reaction mixture was heated to reflux for 2 hours. After completion of the reaction, the mixture was concentrated and the residue was poured into ice water. The aqueous phase was extracted with ethyl acetate and the organic phase was combined. The organic phase was dried over anhydrous sodium sulfate, concentrated, and separated and purified by silica gel column chromatography to finally obtain 2-hydroxy-4-methylbenzonitrile (16 g).
References
[1] Journal of the Chemical Society, 1949, p. 885,889
[2] Patent: CN108117510, 2018, A. Location in patent: Paragraph 0020; 0023; 0024
2-HYDROXY-4-METHYL-BENZONITRILE Preparation Products And Raw materials
Raw materials
Preparation Products
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