ChemicalBook > CAS DataBase List > 2-HYDROXY-4-METHYL-BENZONITRILE

2-HYDROXY-4-METHYL-BENZONITRILE

Product Name
2-HYDROXY-4-METHYL-BENZONITRILE
CAS No.
18495-14-2
Chemical Name
2-HYDROXY-4-METHYL-BENZONITRILE
Synonyms
2-Hydroxy-4-methyk-benzonitrile;2-HYDROXY-4-METHYL-BENZONITRILE;Benzonitrile, 2-hydroxy-4-Methyl-
CBNumber
CB4208996
Molecular Formula
C8H7NO
Formula Weight
133.15
MOL File
18495-14-2.mol
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2-HYDROXY-4-METHYL-BENZONITRILE Property

Melting point:
87 °C
Boiling point:
286.0±28.0 °C(Predicted)
Density 
1.17±0.1 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
7.28±0.10(Predicted)
Appearance
Light brown to yellow Solid
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Safety

HS Code 
2926907090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
H633090
Product name
2-Hydroxy-4-methylbenzonitrile
Packaging
250mg
Price
$45
Updated
2021/12/16
AK Scientific
Product number
W3997
Product name
2-Hydroxy-4-methyl-benzonitrile
Packaging
5g
Price
$171
Updated
2021/12/16
Apolloscientific
Product number
OR903861
Product name
2-Hydroxy-4-methylbenzonitrile
Purity
98%
Packaging
5g
Price
$218
Updated
2021/12/16
AK Scientific
Product number
W3997
Product name
2-Hydroxy-4-methyl-benzonitrile
Packaging
10g
Price
$237
Updated
2021/12/16
Apolloscientific
Product number
OR903861
Product name
2-Hydroxy-4-methylbenzonitrile
Purity
98%
Packaging
10g
Price
$377
Updated
2021/12/16
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2-HYDROXY-4-METHYL-BENZONITRILE Chemical Properties,Usage,Production

Synthesis

84159-60-4

18495-14-2

2-Hydroxy-4-methylbenzaldehyde oxime (23 g) was added to 190 mL of acetic anhydride. The reaction mixture was heated to reflux for 2 hours. After completion of the reaction, the mixture was concentrated and the residue was poured into ice water. The aqueous phase was extracted with ethyl acetate and the organic phase was combined. The organic phase was dried over anhydrous sodium sulfate, concentrated, and separated and purified by silica gel column chromatography to finally obtain 2-hydroxy-4-methylbenzonitrile (16 g).

References

[1] Journal of the Chemical Society, 1949, p. 885,889
[2] Patent: CN108117510, 2018, A. Location in patent: Paragraph 0020; 0023; 0024

2-HYDROXY-4-METHYL-BENZONITRILE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-HYDROXY-4-METHYL-BENZONITRILE Suppliers

3B Pharmachem (Wuhan) International Co.,Ltd.
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821-50328103-801 18930552037
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3bsc@sina.com
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China
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Energy Chemical
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China
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Beijing Eternalchem Co,. Ltd.
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010-59484199 18611897322
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Hunan Hui Bai Shi Biotechnology Co., Ltd.
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Shanghai Topbiochem Technology Co., Ltd
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9ding chemical ( Shanghai) Limited
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Tianjin Ji Ping Jia Chemical Co., Ltd.
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China
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HBCChem, Inc.
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