ChemicalBook > CAS DataBase List > BOC-ORN(BOC)-OH

BOC-ORN(BOC)-OH

Product Name
BOC-ORN(BOC)-OH
CAS No.
57133-29-6
Chemical Name
BOC-ORN(BOC)-OH
Synonyms
BOC-L-ORN(BOC);BOC-ORN(BOC)-OH;BOC-L-ORN(BOC)-OH;BOC-ORNITHINE(BOC)-OH;N,N'-Bis-Boc-L-ornithine;N2,N5-Di-Boc-L-ornithine;Nα,δ-Bis-Boc-L-ornithine;N-ALPHA,DELTA-BIS-BOC-L-ORNITHINE;(Tert-Butoxy)Carbonyl Orn(Boc)-OH;Nα,δ-Bis-Boc-L-ornithine≥ 98% (HPLC)
CBNumber
CB4212164
Molecular Formula
C15H28N2O6
Formula Weight
332.39
MOL File
57133-29-6.mol
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BOC-ORN(BOC)-OH Property

Boiling point:
504.1±45.0 °C(Predicted)
Density 
1.123±0.06 g/cm3(Predicted)
refractive index 
1.478
storage temp. 
Sealed in dry,2-8°C
pka
3.96±0.21(Predicted)
form 
solid
Appearance
White to off-white Solid
optical activity
-6.56°(C=0.90g/100mL, DMF, 20°C, 589nm)
CAS DataBase Reference
57133-29-6(CAS DataBase Reference)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
CDS004042
Product name
boc-orn(boc)-oh
Purity
AldrichCPR
Packaging
250mg
Price
$61.6
Updated
2023/01/07
Activate Scientific
Product number
AS91741
Product name
N2,N5-Di-Boc-L-ornithine
Purity
98+% ee
Packaging
5G
Price
$62
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB38042
Product name
Boc-Orn(Boc)-OH
Packaging
10g
Price
$80
Updated
2021/12/16
Iris Biotech GmbH
Product number
BAA1120
Product name
Boc-L-Orn(Boc)-OH
Packaging
5G
Price
$81
Updated
2021/12/16
Chem-Impex
Product number
04008
Product name
BisBoc-L-ornithine
Purity
≥ 98% (HPLC)
Packaging
25G
Price
$95
Updated
2021/12/16
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BOC-ORN(BOC)-OH Chemical Properties,Usage,Production

Uses

Boc-Orn(Boc)-OH, is an amino acid building block used in peptide synthesis. With a growing peptide drug market the fast, reliable synthesis of peptides is of great importance.

Synthesis

24424-99-5

3184-13-2

57133-29-6

The general procedure for the synthesis of (2S)-2,5-bis[(tert-butoxycarbonyl)amino]pentanoic acid from di-tert-butyl dicarbonate and L-ornithine hydrochloride was as follows: (S)-2,5-diaminopentanoic acid hydrochloride (1a) (337 mg, 2 mmol), di-tert-butyl dicarbonate ((Boc)2O) (1310 mg, 6 mmol), and triethylamine (Et3N) ( 404 mg, 4 mmol) were dissolved in a solvent mixture of 20 mL of acetone and 10 mL of water. The reaction mixture was stirred at room temperature for 12 hours. Upon completion of the reaction, the solvent and triethylamine were removed using a rotary evaporator. The residue was extracted with dichloromethane (20 mL x 3). The organic phases were combined and concentrated to give the target product (2S)-2,5-bis[(tert-butoxycarbonyl)amino]pentanoic acid (2a) as a colorless liquid in 96% yield.

References

[1] Chinese Chemical Letters, 2018, vol. 29, # 6, p. 977 - 980
[2] Journal of the American Chemical Society, 2006, vol. 128, # 12, p. 3998 - 4006
[3] PLoS ONE, 2014, vol. 9, # 9,

BOC-ORN(BOC)-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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BOC-ORN(BOC)-OH Suppliers

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View Lastest Price from BOC-ORN(BOC)-OH manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd
Product
BOC-Orn(Boc)-OH 57133-29-6
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1T
Release date
2023-11-16
Career Henan Chemical Co
Product
BOC-ORN(BOC)-OH 57133-29-6
Price
US $3.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
200KG
Release date
2020-01-12

57133-29-6, BOC-ORN(BOC)-OHRelated Search:

BOC-ORN(2-CL-Z)-OH BOC-ORN-OH BOC-ORN(FMOC)-OH N-tert-Butoxycarbonyl-N'-benzyloxycarbonyl-L-ornithine BOC-CIS-1,4-AMINO-1-CYCLOHEXANE CARBOXYLIC ACID BOC-TRANS-1,4-AMINO-1-CYCLOHEXANE CARBOXYLIC ACID BOC-L-TRANSPRO(4-CH2NH-BOC) BOC4-SPER-CO2H BOC-ORN(BOC)-OH BOC-(2S)-GLY-4PIP-BOC

  • N,N'-DI-(TERT-BUTYLOXYCARBONYL)-L-ORNITHINE
  • N,N'-DI-(T-BUTYLOXYCARBONYL)-L-ORNITHINE
  • N-ALPHA,N-DELTA-DI-T-BUTOXYCARBONYL-L-ORNITHINE
  • N-ALPHA,DELTA-BIS-BOC-L-ORNITHINE
  • N,N'-Bis-Boc-L-ornithine
  • (S)-2,5-Bis((tert-butoxycarbonyl)amino)pentanoic acid
  • BOC-L-ORN(BOC)
  • BOC-L-ORN(BOC)-OH
  • BOC-ORN(BOC)-OH
  • BOC-ORNITHINE(BOC)-OH
  • (2S)-2,5-Bis[[[(tert-butoxy)carbonyl]amino]]pentanoic acid
  • (Tert-Butoxy)Carbonyl Orn(Boc)-OH
  • (2S)-2,5-bis[(2-methylpropan-2-yl)oxycarbonylamino]pentanoic acid
  • N2,N5-Di-Boc-L-ornithine
  • L-Ornithine, N2,N5-bis[(1,1-dimethylethoxy)carbonyl]-
  • Nα,δ-Bis-Boc-L-ornithine≥ 98% (HPLC)
  • 2,5-bis[[(2-methylpropan-2-yl)oxy-oxomethyl]amino]pentanoic acid
  • Nα,δ-Bis-Boc-L-ornithine
  • N-alpha-N'-Di-(t-butyloxycarbonyl)-L-ornithine
  • 57133-29-6