7-chlorothiazolo[5,4-d]pyrimidine
- Product Name
- 7-chlorothiazolo[5,4-d]pyrimidine
- CAS No.
- 13316-12-6
- Chemical Name
- 7-chlorothiazolo[5,4-d]pyrimidine
- Synonyms
- SKL426;7-chlorothiazolo[5,4-d]pyrimidine;Thiazolo[5,4-d]pyriMidine, 7-chloro-;7-chloro-[1,3]thiazolo[5,4-d]pyrimidine
- CBNumber
- CB42123963
- Molecular Formula
- C5H2ClN3S
- Formula Weight
- 171.61
- MOL File
- 13316-12-6.mol
7-chlorothiazolo[5,4-d]pyrimidine Property
- Melting point:
- 152-154℃
- Boiling point:
- 295℃
- Density
- 1.639
- Flash point:
- 132℃
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- form
- solid
- Appearance
- Light yellow to brown Solid
- InChI
- InChI=1S/C5H2ClN3S/c6-4-3-5(8-1-7-4)10-2-9-3/h1-2H
- InChIKey
- HGYFXAHDBRHZGF-UHFFFAOYSA-N
- SMILES
- C1=NC(Cl)=C2N=CSC2=N1
Safety
- HS Code
- 2934999090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- C380633
- Product name
- 7-Chlorothiazolo[5,4-d]pyrimidine
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- FC140240
- Product name
- 7-Chlorothiazolo[5,4-d]pyrimidine
- Packaging
- 500mg
- Price
- $95
- Updated
- 2021/12/16
- Product number
- OR903749
- Product name
- 7-Chlorothiazolo[5,4-d]pyrimidine
- Purity
- 95%
- Packaging
- 250mg
- Price
- $153
- Updated
- 2021/12/16
- Product number
- FC140240
- Product name
- 7-Chlorothiazolo[5,4-d]pyrimidine
- Packaging
- 1g
- Price
- $164
- Updated
- 2021/12/16
- Product number
- 090179
- Product name
- 7-Chlorothiazolo[5,4-d]pyrimidine
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $168
- Updated
- 2021/12/16
7-chlorothiazolo[5,4-d]pyrimidine Chemical Properties,Usage,Production
Synthesis
122-51-0
54851-35-3
13316-12-6
General procedure for the synthesis of 7-chlorothiazolo[5,4-d]pyrimidine from triethyl orthoformate and 5-amino-6-chloropyrimidine-4-thiol: 5-amino-6-chloropyrimidine-4-thiol (4 g, 24.75 mmol) was dissolved in triethyl orthoformate and heated and refluxed for 1 hour. Upon completion of the reaction, the reaction mixture was concentrated to 60% of the original volume and subsequently cooled in a refrigerator. The precipitated solid was collected by filtration and dried under vacuum to afford 7-chlorothiazolo[5,4-d]pyrimidine (2.8 g, 66.04% yield) as a brown solid.1H NMR (300 MHz, CDCl3): δ 9.22 (s, 1H), 8.97 (s, 1H).
References
[1] Patent: WO2010/14930, 2010, A2. Location in patent: Page/Page column 50
[2] Patent: WO2008/57402, 2008, A2. Location in patent: Page/Page column 61-62
[3] Chemical and pharmaceutical bulletin, 1968, vol. 16, # 4, p. 750 - 755
[4] Patent: US2012/122838, 2012, A1. Location in patent: Page/Page column 81
[5] Patent: WO2013/12918, 2013, A1. Location in patent: Paragraph 00533
7-chlorothiazolo[5,4-d]pyrimidine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 7-chlorothiazolo[5,4-d]pyrimidine manufacturers
- Product
- 7-Chlorothiazolo[5,4-d]pyriMidine 13316-12-6
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20T
- Release date
- 2020-05-15