tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate

Product Name: tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate
CAS No.: 1048970-17-7
Chemical Name: tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate
Synonyms: 1-BOC-PIPERIDINE-4-BORONIC ACID PINACOL ESTER;tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pi...;1-Boc-piperidin-4-yl;1-BOC-PIPERIDINE-4-BORONI...;N-Boc-piperidine-4-boronic acid pinacoL;1-Boc-piperidine-4-boronic acid picol ester;N-Boc-piperidine-4-boronic acid pinacol ester;1-Boc-piperidin-4-ylboronic acid pinacol ester;1-N-Boc-piperidine-4-boronic acid pinacol ester;N-Boc-piperidine-4-boronic acid pinacol ester
CBNumber: CB42129349
Molecular Formula: C16H30BNO4
Formula Weight: 311.22
MOL File: 1048970-17-7.mol

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tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate Property

Melting point:: 60-65°C
Boiling point:: 358.8±35.0 °C(Predicted)
Density: 1.03
storage temp.: 2-8°C
pka: -1.07±0.40(Predicted)
form: solid
color: White
InChIKey: IBLQMWKHENBVJE-UHFFFAOYSA-N
CAS DataBase Reference: 1048970-17-7

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26
WGK Germany: 3
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 715387
Product name: N-Boc-piperidine-4-boronic acid pinacol ester
Purity: 97%
Packaging: 250mg
Price: $27.79
Updated: 2025/07/31

Sigma-Aldrich

Product number: 715387
Product name: N-Boc-piperidine-4-boronic acid pinacol ester
Purity: 97%
Packaging: 1g
Price: $99.9
Updated: 2025/07/31

TRC

Product number: B663853
Product name: 1-Boc-piperidin-4-ylboronicAcidPinacolEster
Packaging: 1g
Price: $75
Updated: 2021/12/16

Usbiological

Product number: 263595
Product name: N-Boc-piperidine-4-boronic acid pinacol ester
Packaging: 50mg
Price: $322
Updated: 2021/12/16

AK Scientific

Product number: Y6903
Product name: tert-Butyl4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate
Packaging: 10g
Price: $324
Updated: 2021/12/16

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tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate Chemical Properties,Usage,Production

Uses

1-Boc-piperidin-4-ylboronic acid, pinacol ester

Synthesis

375853-82-0

1048970-17-7

General procedure for the synthesis of 1-N-tert-butoxycarbonylpiperidine-4-boronic acid pinacol ester from 1,2,3,6-tetrahydro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine: method 4: general conditions for the reduction of tetrahydropyridines to piperidines in the presence of boronic acid ester: the boronic acid ester was dissolved in a mixed solvent of ethyl acetate and methanol (1:1 v/v) , with a final borate concentration of 0.4 M) in a mixture of ethyl acetate and methanol, followed by the addition of palladium hydroxide (0.35 equiv). The reaction mixture was stirred under hydrogen atmosphere for 14 hours. Upon completion of the reaction, the reaction mixture was filtered and concentrated in vacuum to give the target piperidine product in quantitative yield. Example 8: Piperidine 8 was prepared from compound 1 in a two-step reaction using Method 4, followed by deprotection of pinacol esters using Method 2. [M-H]? = 228.2 m/z. activity: b

References

[1] Patent: WO2010/118159, 2010, A1. Location in patent: Page/Page column 64-65; 67-68

tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate Suppliers

Belgium 1 China 120 France 1 India 3 United Kingdom 4 United States 15 Global 144

Maybridge Chemical Co., Ltd.

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Country: Belgium
ProdList: 6293
Advantage: 73

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View Lastest Price from tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate 1048970-17-7
Price: US $3.00-9.00/KG
Min. Order: 0.1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2025-07-05

Henan Aochuang Chemical Co.,Ltd.

Product: N-Boc-piperidine-4-boronic acid pinacol ester 1048970-17-7
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-27

Career Henan Chemical Co

Product: tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate 1048970-17-7
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: JD 803
Release date: 2019-09-02

1048970-17-7, tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylateRelated Search:

2-Cyclopropyl-4-(4-fluorophenyl)-quinolyl-3-methanol Deionized water N,N'-Ethylenebis(stearamide) Sulfanilamide N-ACETYLLACTOSAMINE tert-butyl 4-broMo-5,6-dihydropyridine-1(2H)-carboxylate tert-butyl 4-(2-tosylhydrazono)piperidine-1-carboxylate tert-Butyl 3-Methyl-1H-pyrazole-1-carboxylate tert-butyl 4-(5-isopropoxy-2-methyl-4-nitrophenyl)piperidine-1-carboxylate tert-butyl 4-(4-aMino-5-isopropoxy-2-Methylphenyl)piperidine-1-carboxylate TERT-BUTYL 4-(3-BROMOBENZYL)PIPERAZINE-1-CARBOXYLATE 1-N-BOC-4-(4-CHLOROPHENYL)PIPERIDINE tert-butyl 4-(4-iodopyridin-2-yl)piperazine-1-carboxylate tert-Butyl 4-bromo-3,5-dimethyl-1H-pyrazole-1-carboxylate 1-Piperidinecarboxylic acid, 4-(4-methylphenyl)-, 1,1-dimethylethyl ester tert-butyl 4-(5-chloro-2-hydroxyphenyl)-1H-pyrazole-1-carboxylate Boronic acid, (1-methyl-4-piperidinyl)- (9CI) tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate

1-Boc-piperidin-4-ylboronic acid pinacol ester

1-BOC-PIPERIDINE-4-BORONIC ACID PINACOL ESTER

TERT-BUTOXYCARBONYLPIPERIDINE-4-BORONIC ACID, PINACOL ESTER

N-Boc-piperidine-4-boronic acid pinacol ester

Tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidin-1-carboxylate

1-Piperidinecarboxylic acid, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, 1,1-dimethylethyl ester

1-(tert-Butoxycarbonyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine, tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate

Piperidine-4-boronic acid, pinacol ester, N-BOC protected 97%

tert-butyl 4-(tetraMethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate

Tert-Butyl 4-(4,4,5,5-tertraMethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate

1-BOC-PIPERIDINE-4-BORONI...

1-N-Boc-piperidine-4-boronic acid pinacol ester

1-Boc-piperidin-4-yl

tert-butyl 4-(hydroxy((3-hydroxy-2,3-dimethylbutan-2-yl)oxy)boryl)piperidine-1-carboxylate

tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate

Piperidine-4-boronic acid, pinacol ester, N-BOC protected

1-Boc-piperidine-4-boronic acid picol ester

N-Boc-piperidine-4-boronic acid pinacoL

tert-butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pi...

1,1-Dimethylethyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-piperidinecarboxylate

Tert-Butyl 4-(4,4,5,5-tetaramethyl-1,3,2-dioxaborolan-2-yDpiperidine -1-carboxylate

<i>N</i>-Boc-piperidine-4-boronic acid pinacol ester

1-BOC-Piperidine-4-boronic acid pinacol ester - [B7812]

tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-piperidinecarboxylate

1048970-17-7

C16H30BNO4

Alkyl

Organoborons