Sar-Arg-Val-Tyr-Ile-His-Pro-Phe-OH

Product Name: Sar-Arg-Val-Tyr-Ile-His-Pro-Phe-OH
CAS No.: 51833-69-3
Chemical Name: Sar-Arg-Val-Tyr-Ile-His-Pro-Phe-OH
Synonyms: (Sar?)-Angiotensin II;SAR-ARG-VAL-TYR-ILE-HIS-PRO-PHE-OH;Angiotensin II, 1-(N-methylglycine)-5-L-isoleucine-
CBNumber: CB42131164
Molecular Formula: C49H71N13O10
Formula Weight: 1002.17
MOL File: 51833-69-3.mol

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Sar-Arg-Val-Tyr-Ile-His-Pro-Phe-OH Property

storage temp.: Store at -20°C
form: Solid
color: White to off-white
Water Solubility: Soluble in DMSO; 50mg /ml in Water

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Hazard and Precautionary Statements (GHS)

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Sar-Arg-Val-Tyr-Ile-His-Pro-Phe-OH Chemical Properties,Usage,Production

Uses

(Sar1)-Angiotensin II, an analogue of Angiotensin II, is a specific agonist of angiotensin AT1 receptor. (Sar1)-Angiotensin II binds to brain membrane-rich particles, with a Kd of 2.7 nM. (Sar1)-Angiotensin II can stimulate protein synthesis and cell growth in embryonic chick myocytes[1][2][3].

IC 50

AT1 Receptor

References

[1] Matsoukas JM, et, al. Differences in backbone structure between angiotensin II agonists and type I antagonists. J Med Chem. 1995 Nov 10;38(23):4660-9. DOI:10.1021/jm00023a005
[2] Aceto JF, et, al. [Sar1]angiotensin II receptor-mediated stimulation of protein synthesis in chick heart cells. Am J Physiol. 1990 Mar;258(3 Pt 2):H806-13. DOI:10.1152/ajpheart.1990.258.3.H806
[3] Millan MA, et, al. Distribution of angiotensin II receptors in the brain of nonhuman primates. Peptides. Mar-Apr 1990;11(2):243-53. DOI:10.1016/0196-9781(90)90077-i

Sar-Arg-Val-Tyr-Ile-His-Pro-Phe-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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51833-69-3, Sar-Arg-Val-Tyr-Ile-His-Pro-Phe-OHRelated Search:

SAR-ARG-VAL-TYR-ILE-HIS-PRO-PHE

SAR-ARG-VAL-TYR-ILE-HIS-PRO-PHE-OH

Angiotensin II, 1-(N-methylglycine)-5-L-isoleucine-

(Sar?)-Angiotensin II

51833-69-3