(25β)-16,28-Seco-5α-solanid-22(28)-ene-3β,16α-diol
- Product Name
- (25β)-16,28-Seco-5α-solanid-22(28)-ene-3β,16α-diol
- CAS No.
- 2385-18-4
- Chemical Name
- (25β)-16,28-Seco-5α-solanid-22(28)-ene-3β,16α-diol
- Synonyms
- Solafloridine;(25β)-16,28-Seco-5α-solanid-22(28)-ene-3β,16α-diol;Pregnane-3,16-diol, 20-[(5R)-3,4,5,6-tetrahydro-5-methyl-2-pyridinyl]-, (3β,5α,16α,20S)- (9CI)
- CBNumber
- CB42192189
- Molecular Formula
- C27H45NO2
- Formula Weight
- 415.65
- MOL File
- 2385-18-4.mol
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(25β)-16,28-Seco-5α-solanid-22(28)-ene-3β,16α-diol Property
- Melting point:
- 162-5°C (172-5°C)
- Boiling point:
- 534.0±15.0 °C(Predicted)
- Density
- 1.25±0.1 g/cm3(Predicted)
- pka
- 15.08±0.70(Predicted)
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(25β)-16,28-Seco-5α-solanid-22(28)-ene-3β,16α-diol Chemical Properties,Usage,Production
Description
This alkaloid, obtained from Solanum congestijlorum Dun. DC., has the lower of the above two melting points when crystallized rapidly and the higher when crystallized slowly from organic solvents. It is dextrorotatory with [α]20D + 122.7° (c 1.15, CHC13). Treatment with AC20 in pyridine gives the tracetate which is not crystallizable. Hydrogenation over Pt02 yields the dihydro derivative, m.p. 282-5°C; [α]20D + 25.9° (c 0.424, CHCl3).
References
Sato et al., J. Org. Chem., 34, 1577 (1969)
(25β)-16,28-Seco-5α-solanid-22(28)-ene-3β,16α-diol Preparation Products And Raw materials
Raw materials
Preparation Products
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