ChemicalBook > CAS DataBase List > 4-BENZYLOXY-3-METHOXYACETOPHENONE

4-BENZYLOXY-3-METHOXYACETOPHENONE

Product Name
4-BENZYLOXY-3-METHOXYACETOPHENONE
CAS No.
1835-11-6
Chemical Name
4-BENZYLOXY-3-METHOXYACETOPHENONE
Synonyms
NSC 201234;FMX15114-A1;dopamine-002;TIMTEC-BB SBB008382;Acetovanillone benzyl ether;4-BENZYLOXY-3-METHOXYACETOPHENONE;4'-Benzyloxy-3'-methoxyacetophenone;3'-Methoxy-4'-(benzyloxy)acetophenone;4’-(benzyloxy)-3’-methoxy-acetophenon;Acetophenone, 4'-(benzyloxy)-3'-methoxy-
CBNumber
CB4231709
Molecular Formula
C16H16O3
Formula Weight
256.3
MOL File
1835-11-6.mol
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4-BENZYLOXY-3-METHOXYACETOPHENONE Property

Melting point:
85-87°C
Boiling point:
396.5±27.0 °C(Predicted)
Density 
1.115±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Acetonitrile (Slightly), Dichloromethane (Slightly), DMSO (Slightly, Heated)
form 
Solid
color 
White to Off-White
BRN 
1885776
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Safety

Safety Statements 
22-24/25
RTECS 
AM5966000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
B286545
Product name
1-(4-Benzyloxy-3-methoxyphenyl)ethanone
Packaging
5g
Price
$295
Updated
2021/12/16
Matrix Scientific
Product number
074594
Product name
1-(4-(Benzyloxy)-3-methoxyphenyl)ethanone
Purity
95+%
Packaging
1g
Price
$61
Updated
2021/12/16
Matrix Scientific
Product number
074594
Product name
1-(4-(Benzyloxy)-3-methoxyphenyl)ethanone
Purity
95+%
Packaging
5g
Price
$116
Updated
2021/12/16
Biosynth Carbosynth
Product number
FB18464
Product name
1-(4-Benzyloxy-3-methoxyphenyl)ethanone
Packaging
250mg
Price
$125
Updated
2021/12/16
Matrix Scientific
Product number
074594
Product name
1-(4-(Benzyloxy)-3-methoxyphenyl)ethanone
Purity
95+%
Packaging
10g
Price
$214
Updated
2021/12/16
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4-BENZYLOXY-3-METHOXYACETOPHENONE Chemical Properties,Usage,Production

Chemical Properties

Pale Yellow Solid

Uses

Intermediate in the preparation of Epinephrine metabolites

Synthesis

100-39-0

498-02-2

1835-11-6

The general procedure for the synthesis of 4-benzyloxy-3-methoxyacetophenone from benzyl bromide and vanillylacetophenone was as follows: 4-hydroxy-3-methoxyacetophenone (40 g, 240 mmol), benzyl bromide (31.4 mL, 260 mmol), and potassium carbonate (99.6 g, 360 mmol) were dissolved in N,N-dimethylformamide (DMF, 800 mL) and the reaction The mixture was heated to 40 °C and stirred overnight. After completion of the reaction, the mixture was cooled to room temperature, poured into ice water and the solid product precipitated was collected by filtration. The solid product was washed with water and dried to give 1-(4-benzyloxy-3-methoxyphenyl)ethanone (61 g, 99% yield).

References

[1] Patent: WO2005/30140, 2005, A2. Location in patent: Page/Page column 198
[2] Journal of Agricultural and Food Chemistry, 2017, vol. 65, # 19, p. 3965 - 3974
[3] Patent: WO2006/108059, 2006, A1. Location in patent: Page/Page column 87
[4] Patent: WO2005/30140, 2005, A2. Location in patent: Page/Page column 198
[5] Bioorganic and Medicinal Chemistry, 2002, vol. 10, # 3, p. 675 - 683

4-BENZYLOXY-3-METHOXYACETOPHENONE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-BENZYLOXY-3-METHOXYACETOPHENONE Suppliers

J & K SCIENTIFIC LTD.
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18210857532; 18210857532
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86-10-82849933
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jkinfo@jkchemical.com
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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4006356688 18621169109
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Shanghai Sphchem Co., Ltd.
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028-85114309 18982182443
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View Lastest Price from 4-BENZYLOXY-3-METHOXYACETOPHENONE manufacturers

Weijer International Trade (Hebei) Co., Ltd.
Product
4-BENZYLOXY-3-METHOXYACETOPHENONE 1835-11-6
Price
US $30.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
5 Tons Per Day
Release date
2021-09-27
Jinan Ande Pharmaceutical Co.,Ltd.
Product
1-(4-Benzyloxy-3-Methoxyphenyl)ethanone 1835-11-6
Price
US $0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1000
Release date
2021-12-23
Qiuxian Baitai New Material Co., LTD
Product
4-Benzyloxy-3-methoxyacetophenone 1835-11-6
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200000pcs
Release date
2021-03-25

1835-11-6, 4-BENZYLOXY-3-METHOXYACETOPHENONERelated Search:


  • TIMTEC-BB SBB008382
  • 1-(3-methoxy-4-(phenylmethoxy)phenyl)ethanone
  • 4’-(benzyloxy)-3’-methoxy-acetophenon
  • Acetophenone, 4'-(benzyloxy)-3'-methoxy-
  • Ethanone, 1-(3-methoxy-4-(phenylmethoxy)phenyl)-
  • 1-[4-(BENZYLOXY)-3-METHOXYPHENYL]ETHANONE
  • dopamine-002
  • 4-BENZYLOXY-3-METHOXYACETOPHENONE
  • 3'-Methoxy-4'-(benzyloxy)acetophenone
  • Acetovanillone benzyl ether
  • NSC 201234
  • 1-[4-(benzyloxy)-3-Methoxyphenyl]ethan-1-one
  • FMX15114-A1
  • 4- benzomethoxy -3- methoxy acetyl benzene
  • 4'-Benzyloxy-3'-methoxyacetophenone
  • 1835-11-6
  • Aromatic Acetophenones & Derivatives (substituted)
  • Aromatics
  • Intermediates