4-BENZYLOXY-3-METHOXYACETOPHENONE
- Product Name
- 4-BENZYLOXY-3-METHOXYACETOPHENONE
- CAS No.
- 1835-11-6
- Chemical Name
- 4-BENZYLOXY-3-METHOXYACETOPHENONE
- Synonyms
- NSC 201234;FMX15114-A1;dopamine-002;TIMTEC-BB SBB008382;Acetovanillone benzyl ether;4-BENZYLOXY-3-METHOXYACETOPHENONE;4'-Benzyloxy-3'-methoxyacetophenone;3'-Methoxy-4'-(benzyloxy)acetophenone;4’-(benzyloxy)-3’-methoxy-acetophenon;Acetophenone, 4'-(benzyloxy)-3'-methoxy-
- CBNumber
- CB4231709
- Molecular Formula
- C16H16O3
- Formula Weight
- 256.3
- MOL File
- 1835-11-6.mol
4-BENZYLOXY-3-METHOXYACETOPHENONE Property
- Melting point:
- 85-87°C
- Boiling point:
- 396.5±27.0 °C(Predicted)
- Density
- 1.115±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Acetonitrile (Slightly), Dichloromethane (Slightly), DMSO (Slightly, Heated)
- form
- Solid
- color
- White to Off-White
- BRN
- 1885776
Safety
- Safety Statements
- 22-24/25
- RTECS
- AM5966000
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B286545
- Product name
- 1-(4-Benzyloxy-3-methoxyphenyl)ethanone
- Packaging
- 5g
- Price
- $295
- Updated
- 2021/12/16
- Product number
- 074594
- Product name
- 1-(4-(Benzyloxy)-3-methoxyphenyl)ethanone
- Purity
- 95+%
- Packaging
- 1g
- Price
- $61
- Updated
- 2021/12/16
- Product number
- 074594
- Product name
- 1-(4-(Benzyloxy)-3-methoxyphenyl)ethanone
- Purity
- 95+%
- Packaging
- 5g
- Price
- $116
- Updated
- 2021/12/16
- Product number
- FB18464
- Product name
- 1-(4-Benzyloxy-3-methoxyphenyl)ethanone
- Packaging
- 250mg
- Price
- $125
- Updated
- 2021/12/16
- Product number
- 074594
- Product name
- 1-(4-(Benzyloxy)-3-methoxyphenyl)ethanone
- Purity
- 95+%
- Packaging
- 10g
- Price
- $214
- Updated
- 2021/12/16
4-BENZYLOXY-3-METHOXYACETOPHENONE Chemical Properties,Usage,Production
Chemical Properties
Pale Yellow Solid
Uses
Intermediate in the preparation of Epinephrine metabolites
Synthesis
100-39-0
498-02-2
1835-11-6
The general procedure for the synthesis of 4-benzyloxy-3-methoxyacetophenone from benzyl bromide and vanillylacetophenone was as follows: 4-hydroxy-3-methoxyacetophenone (40 g, 240 mmol), benzyl bromide (31.4 mL, 260 mmol), and potassium carbonate (99.6 g, 360 mmol) were dissolved in N,N-dimethylformamide (DMF, 800 mL) and the reaction The mixture was heated to 40 °C and stirred overnight. After completion of the reaction, the mixture was cooled to room temperature, poured into ice water and the solid product precipitated was collected by filtration. The solid product was washed with water and dried to give 1-(4-benzyloxy-3-methoxyphenyl)ethanone (61 g, 99% yield).
References
[1] Patent: WO2005/30140, 2005, A2. Location in patent: Page/Page column 198
[2] Journal of Agricultural and Food Chemistry, 2017, vol. 65, # 19, p. 3965 - 3974
[3] Patent: WO2006/108059, 2006, A1. Location in patent: Page/Page column 87
[4] Patent: WO2005/30140, 2005, A2. Location in patent: Page/Page column 198
[5] Bioorganic and Medicinal Chemistry, 2002, vol. 10, # 3, p. 675 - 683
4-BENZYLOXY-3-METHOXYACETOPHENONE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-BENZYLOXY-3-METHOXYACETOPHENONE manufacturers
- Product
- 4-BENZYLOXY-3-METHOXYACETOPHENONE 1835-11-6
- Price
- US $30.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 5 Tons Per Day
- Release date
- 2021-09-27
- Product
- 1-(4-Benzyloxy-3-Methoxyphenyl)ethanone 1835-11-6
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1000
- Release date
- 2021-12-23
- Product
- 4-Benzyloxy-3-methoxyacetophenone 1835-11-6
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200000pcs
- Release date
- 2021-03-25