CIS-CLOMIPHENE HCL
- Product Name
- CIS-CLOMIPHENE HCL
- CAS No.
- 15690-55-8
- Chemical Name
- CIS-CLOMIPHENE HCL
- Synonyms
- Isomer A;RMI-16312;zuclomifene;Zuclomiphene;cis-clomifene;Cisclomifenum;cis-clomiphene;(Z)-Clomiphene;Z-CloMiphene-d4;CIS-CLOMIPHENE HCL
- CBNumber
- CB4232706
- Molecular Formula
- C26H28ClNO
- Formula Weight
- 405.96
- MOL File
- 15690-55-8.mol
CIS-CLOMIPHENE HCL Property
- Melting point:
- 156.5-158.0°
- Boiling point:
- 509.0±50.0 °C(Predicted)
- Density
- 1.104±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: 2mg/mL, clear
- pka
- 9.60±0.25(Predicted)
- form
- powder
- color
- white to beige
- InChI
- InChI=1S/C26H28ClNO/c1-3-28(4-2)19-20-29-24-17-15-22(16-18-24)25(21-11-7-5-8-12-21)26(27)23-13-9-6-10-14-23/h5-18H,3-4,19-20H2,1-2H3/b26-25-
- InChIKey
- GKIRPKYJQBWNGO-QPLCGJKRSA-N
- SMILES
- C(N(CC)CC)COC1=CC=C(/C(/C2=CC=CC=C2)=C(\Cl)/C2=CC=CC=C2)C=C1
N-Bromosuccinimide Price
- Product number
- API0010423
- Product name
- CIS-CLOMIPHENE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $825.3
- Updated
- 2021/12/16
CIS-CLOMIPHENE HCL Chemical Properties,Usage,Production
Uses
Zuclomiphene (compound 23) is a potent inhibitor of 17β-Estradiol (HY-B0141) and can inhibit the secretion of luteinizing hormone (LH)[1].
Definition
ChEBI: Zuclomifene is a stilbenoid.
Biological Activity
Orally available, less active cis isomer of the fertility drug clomiphene; mixed agonist of estrogen receptor.Zuclomiphene is an orally available, less active cis isomer of the fertility drug clomiphene. Zuclomiphene is a mixed agonist of estrogen receptor responsible for the estrogenic activity of clomiphene and therefore the common side effects sometimes seen in males. Similarly, to clomiphene and enclomiphene, zuclomiphene blocks Ebola virus entry and infection in tissue culture cells and affords up to 90% protection in the mouse model of Ebola virus disease.
References
[1] Christian Laggner, et al. Discovery of High-Affinity Ligands of σ1 Receptor, ERG2, and Emopamil Binding Protein by Pharmacophore Modeling and Virtual Screening. J Med Chem. 2005 Jul 28;48(15):4754-64. DOI:10.1021/jm049073+
CIS-CLOMIPHENE HCL Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from CIS-CLOMIPHENE HCL manufacturers
- Product
- cis-clomiphene hcl 15690-55-8
- Price
- US $8.80-2.20/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 100kg
- Release date
- 2025-06-27