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DEFOSLIMOD

Product Name
DEFOSLIMOD
CAS No.
171092-39-0
Chemical Name
DEFOSLIMOD
Synonyms
DEFOSLIMOD;α-D-Glucopyranose, 2-deoxy-6-O-[2-deoxy-2-[[(3R)-1-oxo-3-[(1-oxododecyl)oxy]tetradecyl]amino]-4-O-phosphono-β-D-glucopyranosyl]-2-[[(3R)-3-hydroxy-1-oxotetradecyl]amino]-, 1-(dihydrogen phosphate)
CBNumber
CB42451400
Molecular Formula
C52H100N2O20P2
Formula Weight
1135.3
MOL File
171092-39-0.mol
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DEFOSLIMOD Property

Density 
1.25±0.1 g/cm3(Predicted)
pka
1.73±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
PXT0003440
Product name
DEFOSLIMOD
Purity
95.00%
Packaging
5MG
Price
$501.06
Updated
2021/12/16
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DEFOSLIMOD Chemical Properties,Usage,Production

Uses

Defoslimod (OM 174) is an agonist for TLR4 receptor and acts as an immunomodulator. Defoslimod activates macrophages and dendritic cells, induces cytokines secretion, and exhibits antitumor efficacy in rats[1].

References

[1] Isambert N, et al., Phase I study of OM-174, a lipid A analogue, with assessment of immunological response, in patients with refractory solid tumors. BMC Cancer. 2013 Apr 2;13:172. DOI:10.1186/1471-2407-13-172

DEFOSLIMOD Preparation Products And Raw materials

Raw materials

Preparation Products

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DEFOSLIMOD Suppliers

Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58

171092-39-0, DEFOSLIMODRelated Search:


  • DEFOSLIMOD
  • α-D-Glucopyranose, 2-deoxy-6-O-[2-deoxy-2-[[(3R)-1-oxo-3-[(1-oxododecyl)oxy]tetradecyl]amino]-4-O-phosphono-β-D-glucopyranosyl]-2-[[(3R)-3-hydroxy-1-oxotetradecyl]amino]-, 1-(dihydrogen phosphate)
  • 171092-39-0
  • C52H100N2O20P2