CORTISTATIN-8

Product Name: CORTISTATIN-8
CAS No.: 485803-62-1
Chemical Name: CORTISTATIN-8
Synonyms: CORTISTATIN-8;PCFwKTCK(Disulfide bridge 2 - 7);L-Lysinamide, L-prolyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-, cyclic (2→7)-disulfide
CBNumber: CB42455620
Molecular Formula: C47H68N12O9S2
Formula Weight: 1009.25
MOL File: 485803-62-1.mol

More

Less

CORTISTATIN-8 Property

Boiling point:: 1451.7±65.0 °C(Predicted)
Density: 1.38±0.1 g/cm3(Predicted)
storage temp.: Desiccate at -20°C
solubility: ≥ 100.9mg/mL in DMSO
form: Solid
pka: 12.56±0.70(Predicted)
color: White to off-white
Sequence: Pro-Cys-Phe-{d-Trp}-Lys-Thr-Cys-Lys-NH2 (disulfide bridge: Cys2-Cys7)

More

Less

Hazard and Precautionary Statements (GHS)

More

Less

N-Bromosuccinimide Price

Usbiological

Product number: 255032
Product name: Cortistatin-8
Packaging: 1mg
Price: $480
Updated: 2021/12/16

ApexBio Technology

Product number: B5367
Product name: Cortistatin-8
Packaging: 1mg
Price: $212
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PEP0004468
Product name: CORTISTATIN-8
Purity: 95.00%
Packaging: 5MG
Price: $496.87
Updated: 2021/12/16

More

Less

CORTISTATIN-8 Chemical Properties,Usage,Production

Uses

Cortistatin-8 (CST-8; PCFWKTCK), a neuropeptide, is a GHS-R1a antagonist by counteracting the response of ghrelin on gastric acid secretion. Cortistatin-8 can modulate GH release from somatotroph cells. Cortistatin-8 is a synthetic CST-analogue devoid of any binding affinity to SST-R but capable to bind the GHS-R1a. Cortistatin-8 can exert antagonistic effects on ghrelin actions either in vitro or in vivo in animals[1].

IC 50

GHSR1a

References

[1] F Prodam, et al. Cortistatin-8, a synthetic cortistatin-derived ghrelin receptor ligand, does not modify the endocrine responses to acylated ghrelin or hexarelin in humans. Neuropeptides. 2008 Feb;42(1):89-93. DOI:10.1016/j.npep.2007.09.006

CORTISTATIN-8 Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

CORTISTATIN-8 Suppliers

China 23 United Kingdom 1 United States 2 Global 26

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15838
Advantage: 69

Avantpbc Chemical Tech(Shanghai) Co,Ltd.

Tel: 17802107445
Country: China
ProdList: 185
Advantage: 55

Nanjing Leon Biological Technology Co., Ltd.

Tel: 17705183659
Fax: 84523390
Email: sales@njleonbiotech.com
Country: China
ProdList: 5501
Advantage: 55

Nanjing Peptide Biotech Ltd.

Tel: 025-58361106-805 15951641583
Fax: 025-58361106-806
Email: zhao.xu@njpeptide.com
Country: China
ProdList: 9979
Advantage: 55

Chengdu Youngshe Chemical Co., Ltd.

Tel: +86-17380623303
Fax: 028-62328193
Email: Caroline@youngshechem.com
Country: China
ProdList: 4802
Advantage: 58

Hangzhou Peptidego Biotech Co.,Ltd.

Tel: 0571-87213919
Email: Eric@peptidego.com
Country: China
ProdList: 7408
Advantage: 58

Nanjing Meihao Pharmaceutical Technology Co., Ltd.

Tel: meitaochem@126.com
Email: meitaochem@126.com
Country: China
ProdList: 19103
Advantage: 58

Hangzhou Go Top Peptide Biotech

Tel: 15397062932
Email: sales1@gotopbio.com
Country: China
ProdList: 2923
Advantage: 58

Shaoxing Junyu Biotechnology Co., LTD

Tel: 0571-0571-88211921 19105816207
Email: sales4@gotopbio.com
Country: China
ProdList: 5144
Advantage: 58

Hangzhou Sinoda Pharmaceutical Technology Co. LTD

Tel: 0571-87213919 17306812703
Email: 3007955328@qq.com
Country: China
ProdList: 6979
Advantage: 58

485803-62-1, CORTISTATIN-8Related Search:

CORTISTATIN-8

PCFwKTCK(Disulfide bridge 2 - 7)

L-Lysinamide, L-prolyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-, cyclic (2→7)-disulfide

485803-62-1

C47H68N12O9S2