ChemicalBook > CAS DataBase List > EUK 124

EUK 124

Product Name
EUK 124
CAS No.
186299-35-4
Chemical Name
EUK 124
Synonyms
EUK 124;VCQQGEFBIFYGQL-AIMLMLFYSA-K
CBNumber
CB42456379
Molecular Formula
C20H22ClMnN2O6
Formula Weight
476.79
MOL File
186299-35-4.mol
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EUK 124 Property

solubility 
DMSO: 20 mg/ml; Ethanol: 1 mg/ml; PBS (pH 7.2): 0.2 mg/ml
form 
A crystalline solid
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
12500
Product name
EUK 124
Purity
≥95%
Packaging
5mg
Price
$39
Updated
2024/03/01
Cayman Chemical
Product number
12500
Product name
EUK 124
Purity
≥95%
Packaging
10mg
Price
$73
Updated
2024/03/01
Usbiological
Product number
167822
Product name
EUK-124
Packaging
5mg
Price
$270
Updated
2021/12/16
ApexBio Technology
Product number
C4679
Product name
EUK124
Packaging
10mg
Price
$82
Updated
2021/12/16
AK Scientific
Product number
1672AH
Product name
Chloro[[2,2'-[1,2-ethanediylbis[(nitrilo-kappan)methylidyne]]bis[3,5-dimethoxyphenolato-kappao]](2-)]-manganese
Packaging
5mg
Price
$141
Updated
2021/12/16
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EUK 124 Chemical Properties,Usage,Production

Description

EUK 8 and EUK 134 are synthetic catalytic scavengers of reactive oxygen species with superoxide dismutase (SOD) and catalase mimetic activity.1 EUK 124 is a structural analog of EUK 8 and EUK 134 with significantly reduced activity. EUK 124 and EUK 8 inhibit superoxide-mediated reduction of an electron acceptor (i.e., SOD mimetic activity), with IC50 values of 5 μM and 0.7 μM, respectively.2

References

1. Baker, K., Marcus, C.B., Huffman, K., et al. Synthetic combined superoxide dismutase/catalase mimetics are protective as a delayed treatment in a rat stroke model: A key role for reactive oxygen species in ischemic brain injury J. Pharmacol. Exp. Ther. 284(1),215-221(1998).
2. Doctrow, S.R., Huffman, K., Marcus, C.B., et al. Salen-manganese complexes as catalytic scavengers of hydrogen peroxide and cytoprotective agents: Structure-activity relationship studies J. Med. Chem. 45,4549-4558(2002).

EUK 124 Preparation Products And Raw materials

Raw materials

Preparation Products

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EUK 124 Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
MedBioPharmaceutical Technology Inc
Tel
021-69568360 18916172912
Email
order@med-bio.cn
Country
China
ProdList
8140
Advantage
58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24644
Advantage
58
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
Email
customer_service@efebio.com
Country
China
ProdList
11974
Advantage
58
Shanghai Aladdin Biochemical Technology Co.,Ltd.
Tel
+86-18521732826
Email
market@aladdin-e.com
Country
China
ProdList
48461
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
52924
Advantage
58
Wuhan Topule Biopharmaceutical Co., Ltd
Tel
+8618327326525
Email
masar@topule.com
Country
China
ProdList
8467
Advantage
58
ApexBio Technology
Tel
--
Fax
--
Email
sales@apexbt.com
Country
United States
ProdList
6251
Advantage
58

186299-35-4, EUK 124Related Search:


  • EUK 124
  • VCQQGEFBIFYGQL-AIMLMLFYSA-K
  • 186299-35-4
  • C20H22ClMnN2O6