ChemicalBook > CAS DataBase List > 1,7-Bis-boc-1,4,7-triazaheptane

1,7-Bis-boc-1,4,7-triazaheptane

Product Name
1,7-Bis-boc-1,4,7-triazaheptane
CAS No.
117499-16-8
Chemical Name
1,7-Bis-boc-1,4,7-triazaheptane
Synonyms
Di-tert-butyl (azanediylbis(ethane-2,1-diyl))dicarbaMate;dicarbamate;N,N-di-Boc-diethylenetriamine;1,7-BIS-BOC-1,4,7-TRIAZAHEPTANE;bis(2-tert-butyloxycarbonylaminoethyl)amine;Di-tert-butyl (azanediylbis(ethane-2,1-diyl);N,N-Bis[2-(tert-butoxycarbonylaMino)ethyl]aMine;N1-Boc-N2-[2-(Boc-amino)ethyl]-1,2-ethanediamine;10-Oxa-2,5,8-triazadodecanoic acid, 11,11-dimethyl-9-oxo-, 1,1-dimethylethyl ester;tert-butyl N-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethylamino]ethyl]carbamate
CBNumber
CB42458171
Molecular Formula
C14H29N3O4
Formula Weight
303.4
MOL File
117499-16-8.mol
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1,7-Bis-boc-1,4,7-triazaheptane Property

Melting point:
68-70°C
Boiling point:
440.5±30.0 °C(Predicted)
Density 
1.035±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly)
pka
12.28±0.46(Predicted)
form 
Solid
color 
White to Off-White
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Safety

Safety Statements 
24/25
HS Code 
29225090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H315Causes skin irritation

H318Causes serious eye damage

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P322Specific measures (see …on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
B415105
Product name
N,N-Bis[2-(tert-butoxycarbonylamino)ethyl]amine
Packaging
500mg
Price
$150
Updated
2021/12/16
Usbiological
Product number
266487
Product name
1,7-Bis-Boc-1,4,7-triazaheptane
Packaging
250mg
Price
$408
Updated
2021/12/16
TRC
Product number
B415105
Product name
N,N-Bis[2-(tert-butoxycarbonylamino)ethyl]amine
Packaging
5g
Price
$1190
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
JK1265879
Product name
1,7-Bis-Boc-1,4,7-triazaheptane
Purity
97%
Packaging
250mg
Price
$454
Updated
2021/12/16
SynQuest Laboratories
Product number
4156-1-0D
Product name
1,7-Bis-Boc-1,4,7-triazaheptane
Packaging
1g
Price
$461
Updated
2021/12/16
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1,7-Bis-boc-1,4,7-triazaheptane Chemical Properties,Usage,Production

Description

1,7-BIS-BOC-1,4,7-TRIAZAHEPTANE contains two Boc protecting groups which can be removed under acidic conditions. The remaining free amines can further react with carbonyl moieties.

Chemical Properties

1,7-BIS-BOC-1,4,7-TRIAZAHEPTANE is white powder

Uses

1,7-BIS-BOC-1,4,7-TRIAZAHEPTANE is used in the preparation of bifunctional chelators that have been then applied to the synthesis of monoclonal antibody conjugates for tumor targeting.

in vitro

1,7-Bis-Boc-1,4,7-triazaheptane is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins

1,7-Bis-boc-1,4,7-triazaheptane Preparation Products And Raw materials

Raw materials

Preparation Products

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1,7-Bis-boc-1,4,7-triazaheptane Suppliers

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View Lastest Price from 1,7-Bis-boc-1,4,7-triazaheptane manufacturers

Honest Joy Holdings Limited
Product
tert-butyl N-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethylamino]ethyl]carbamate 117499-16-8
Price
US $0.00/KG
Min. Order
1KG
Purity
98.4%
Supply Ability
100 tons
Release date
2022-01-17

117499-16-8, 1,7-Bis-boc-1,4,7-triazaheptaneRelated Search:

ETHANE

  • 1,7-BIS-BOC-1,4,7-TRIAZAHEPTANE
  • Di-tert-butyl (azanediylbis(ethane-2,1-diyl))dicarbaMate
  • N,N-Bis[2-(tert-butoxycarbonylaMino)ethyl]aMine
  • bis(2-tert-butyloxycarbonylaminoethyl)amine
  • dicarbamate
  • Di-tert-butyl (azanediylbis(ethane-2,1-diyl)
  • 10-Oxa-2,5,8-triazadodecanoic acid, 11,11-dimethyl-9-oxo-, 1,1-dimethylethyl ester
  • tert-butyl N-[2-[2-[(2-methylpropan-2-yl)oxycarbonylamino]ethylamino]ethyl]carbamate
  • N,N-di-Boc-diethylenetriamine
  • N1-Boc-N2-[2-(Boc-amino)ethyl]-1,2-ethanediamine
  • 117499-16-8
  • Miscellaneous Reagents