[4-(2-AMINO-ETHYL)-PHENYL]-CARBAMIC ACID TERT-BUTYL ESTER

Product Name
[4-(2-AMINO-ETHYL)-PHENYL]-CARBAMIC ACID TERT-BUTYL ESTER
CAS No.
457631-44-6
Chemical Name
[4-(2-AMINO-ETHYL)-PHENYL]-CARBAMIC ACID TERT-BUTYL ESTER
Synonyms
4-(2-Aminoethyl)-N-Boc-aniline;tert-Butyl (4-(2-aminoethyl)phenyl)carbamate;[4-(2-AMINO-ETHYL)-PHENYL]-CARBAMIC ACID TERT-BUTYL ESTER;Carbamic acid, N-[4-(2-aminoethyl)phenyl]-, 1,1-dimethylethyl ester
CBNumber
CB42460370
Molecular Formula
C13H20N2O2
Formula Weight
236.31
MOL File
457631-44-6.mol
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[4-(2-AMINO-ETHYL)-PHENYL]-CARBAMIC ACID TERT-BUTYL ESTER Property

Melting point:
89-91 °C
Boiling point:
315.9±25.0 °C(Predicted)
Density 
1.099±0.06 g/cm3(Predicted)
pka
13.79±0.70(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
CHM0125011
Product name
(4-(2-AMINO-ETHYL)-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER
Purity
96.00%
Packaging
1G
Price
$1070.84
Updated
2021/12/16
AK Scientific
Product number
4658AJ
Product name
tert-ButylN-[4-(2-aminoethyl)phenyl]carbamate
Packaging
2.5g
Price
$1451
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0125011
Product name
(4-(2-AMINO-ETHYL)-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER
Purity
96.00%
Packaging
2.5G
Price
$1635.3
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0125011
Product name
(4-(2-AMINO-ETHYL)-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER
Purity
96.00%
Packaging
5G
Price
$2181.31
Updated
2021/12/16
Acrotein
Product number
AM-1079
Product name
tert-Butyl[4-(2-Amino-ethyl)-phenyl]carbamate
Purity
97%
Packaging
0.25g
Price
$132
Updated
2021/12/16
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[4-(2-AMINO-ETHYL)-PHENYL]-CARBAMIC ACID TERT-BUTYL ESTER Chemical Properties,Usage,Production

Synthesis

[4-(2-Amino-ethyl)-phenyl]-carbamic acid tert-butyl ester is synthesised using 4-tert-butoxycarbonylaminophenylacetonitrile as a raw material by chemical reaction. The specific synthesis steps are as follows:
To a solution of (300 gm, 1.29 moles) N-BOC-4-aminophenylacetonitrile in 3000 ml of methanol, 25% aq. ammonia solution (480 ml) and Raney nickel (45 gm) were added at 25 -30°C. Reaction mixture was subjected to hydrogenation at 50-60 PSI for 4 hrs. After completion of reaction, as indicated from TLC, reaction mixture was filtered and washed with (2 X 25 ml) methanol. Filtrate was concentrated under vacuum and resulting residue was treated with (1500 ml) 1M aq. hydrochloric acid at 25-30°C. Reaction mixture was stirred for 15 minutes and filtered to remove insoluble impurities. Filtrate was basified to pH 10-12 with 50% aq. NaOH solution below 25°C. Precipitated 4-(2-aminoethyl)-N-(tert-butoxycarbonyl) phenylamine was filtered and washed with (2 X 100 ml) water. Solid was dried under vacuum at 55- 60°C for 8-10 hrs. Dry weight: 240 gm (79%). 1H NMR (CDC13 and 400 MHz): δ 1.11 (2H, s), 1.51 (9H, s), 2.68 (2H, t), 2.93 (2H, t), 6.72 (1H, s), 7.10 (2H, d), 7.28 (2H, d).

[4-(2-AMINO-ETHYL)-PHENYL]-CARBAMIC ACID TERT-BUTYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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[4-(2-AMINO-ETHYL)-PHENYL]-CARBAMIC ACID TERT-BUTYL ESTER Suppliers

China 13 Global 13
Shanghai XinKai Chemical Technology Co., Ltd.
Tel
021-58930698 15921516558
Fax
86-021-58933679
Email
zhangyichao84@126.com
Country
China
ProdList
910
Advantage
55
JW & Y Pharmlab Co., Ltd.
Tel
021-64340559 13651849907;
Fax
021- 64345308
Email
xinyu_shi@jwypharmlab.com.cn
Country
China
ProdList
12036
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58
BePharm Ltd
Tel
400-685-9117
Fax
021-51816740
Email
market@bepharm.com
Country
China
ProdList
15081
Advantage
60
Shanghai SuperLan Chemcial Technique Centre
Tel
021-2022843681 15618226720
Fax
+86-21-51601218
Email
lucy@atkchemical.com
Country
China
ProdList
9952
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Amatek Scientific Co. Ltd.
Tel
0512-56316828
Fax
0512-56316826
Email
info@amateksci.com
Country
China
ProdList
28806
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58
Hefei Molake Biotechnology Co., Ltd.
Tel
0551-66336380 18956014586
Fax
055166336380
Email
983438788@qq.com
Country
China
ProdList
2158
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58
Shanghai zhigan biotechnology co., LTD
Tel
Email
zhiqianbio@126.com
Country
China
ProdList
19778
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58
Labnetwork lnc.
Tel
+86-27-50766799 +8618062016861
Email
contact@labnetwork.com
Country
China
ProdList
19987
Advantage
58
Shanghai Kaiwei Chemical Technology Co., Ltd.
Tel
021-58461859 15821823057
Email
service@aiviche.com
Country
China
ProdList
49312
Advantage
58
Shanghai Aizikang Pharmaceutical Research Co., Ltd
Tel
18721109360
Email
306685371@qq.com
Country
China
ProdList
1900
Advantage
58
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View Lastest Price from [4-(2-AMINO-ETHYL)-PHENYL]-CARBAMIC ACID TERT-BUTYL ESTER manufacturers

SHANDONG OUCHEM CO.,LTD.
Product
tert-Butyl (4-(2-aminoethyl)phenyl)carbamate 457631-44-6
Price
US $0.00-0.00/kg
Min. Order
0.1kg
Purity
97% Min.
Supply Ability
500kg
Release date
2024-01-18

457631-44-6, [4-(2-AMINO-ETHYL)-PHENYL]-CARBAMIC ACID TERT-BUTYL ESTERRelated Search:

(S)-N-ALPHA-T-BUTYLOXYCARBONYL-4-(T-BUTYLOXYCARBONYL-AMIDO)-PHENYLALANINE BENZYL ESTER (S)-N-9-FLUORENYLMETHYLOXYCARBONYL-7-(N'-T-BUTYLOXYCARBONYL-AMINO)-[1,2,3,4]-TETRAHYDROISOQUINOLINE-3-CARBOXYLIX ACID H-PHE(4-NH-BOC)-OH Fmoc-p(NH-Boc)-L-Phe-OH (4-PIPERIDIN-3-YL-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER [4-(2-AMINO-ETHYL)-PHENYL]-CARBAMIC ACID TERT-BUTYL ESTER BOC-L-PHE(4-NH-BOC) TERT-BUTYL 4-(2-OXO-2-PIPERAZIN-1-YLETHYL)PHENYLCARBAMATE FMOC-PHE(4-NHBOC,3,5-I 2)-OH Tert-butyl 1,2,3,4-tetrahydroisoquinolin-7-ylcarbamate 2-TERT-BUTOXYCARBONYLAMINO-3-(4-TERT-BUTOXYCARBONYLAMINO-PHENYL)-PROPIONIC ACID tert-butyl 4-(pyrrolidin-3-yl)phenylcarbamate BOC-D-PHE(4-NHBOC)-OH Tert-butyl indolin-6-yl-carbamate

  • [4-(2-AMINO-ETHYL)-PHENYL]-CARBAMIC ACID TERT-BUTYL ESTER
  • tert-Butyl (4-(2-aminoethyl)phenyl)carbamate
  • Carbamic acid, N-[4-(2-aminoethyl)phenyl]-, 1,1-dimethylethyl ester
  • 4-(2-Aminoethyl)-N-Boc-aniline
  • 457631-44-6