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3-AMINO-3-METHYL-BUTYRIC ACID ETHYL ESTER HCL

Product Name
3-AMINO-3-METHYL-BUTYRIC ACID ETHYL ESTER HCL
CAS No.
85532-40-7
Chemical Name
3-AMINO-3-METHYL-BUTYRIC ACID ETHYL ESTER HCL
Synonyms
3-Amino-3-methyl-butyric acid eth;ETHYL 3-AMINO-3-METHYLBUTANOATE, HCL;3-aMino-3-Methylhexanoate hydrochloride;Ethyl 3-Amino-3-methylbutyrate Hydrochloride;Ethyl 3-aMino-3-Methylbutanoate hydrochloride;3-AMINO-3-METHYL-BUTYRIC ACID ETHYL ESTER HCL;Ethyl3-Amino-3-methylbutyrateHydrochloride>3-Amino-3-methylbutanoicacidethylesterhydrochloride;3-Amino-3-methyl-butyric acid ethyl ester x HCl, 98%;3-Amino-3-methylbutyric Acid Ethyl Ester Hydrochloride
CBNumber
CB42464868
Molecular Formula
C7H16ClNO2
Formula Weight
181.66
MOL File
85532-40-7.mol
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3-AMINO-3-METHYL-BUTYRIC ACID ETHYL ESTER HCL Property

Melting point:
99.0 to 103.0 °C
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
form 
powder to crystal
color 
White to Almost white
InChIKey
HFBJSIGXRKAYAF-UHFFFAOYSA-N
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Safety

HS Code 
2922498590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H290May be corrosive to metals

H314Causes severe skin burns and eye damage

H341Suspected of causing genetic defects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P234Keep only in original container.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P308+P313IF exposed or concerned: Get medical advice/attention.

P390Absorb spillage to prevent material damage.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P406Store in corrosive resistant/… container with a resistant inner liner.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical
Product number
E0809
Product name
Ethyl 3-Amino-3-methylbutyrate Hydrochloride
Purity
>98.0%(N)
Packaging
1g
Price
$50
Updated
2025/07/31
TCI Chemical
Product number
E0809
Product name
Ethyl 3-Amino-3-methylbutyrate Hydrochloride
Purity
>98.0%(N)
Packaging
5g
Price
$171
Updated
2025/07/31
TRC
Product number
E899543
Product name
Ethyl3-amino-3-methylbutanoatehydrochloride
Packaging
250mg
Price
$55
Updated
2021/12/16
Matrix Scientific
Product number
074637
Product name
Ethyl 3-amino-3-methylbutanoate hydrochloride
Purity
95%
Packaging
1g
Price
$20
Updated
2021/12/16
Matrix Scientific
Product number
074637
Product name
Ethyl 3-amino-3-methylbutanoate hydrochloride
Purity
95%
Packaging
5g
Price
$58
Updated
2021/12/16
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3-AMINO-3-METHYL-BUTYRIC ACID ETHYL ESTER HCL Chemical Properties,Usage,Production

Uses

Ethyl 3-amino-3-methylbutanoate, HCl

Synthesis

638-10-8

85532-40-7

General procedure for the synthesis of 3-amino-3-methylbutanoic acid ethyl ester hydrochloride from 3-methyl-2-butenoic acid ethyl ester: 3-methyl-2-butenoic acid ethyl ester (1 g, 7.8 mmol) was dissolved in anhydrous ethanol (12 mL), cooled to -20 °C and passed through ammonia to saturation. The reaction tube was sealed and the reaction was carried out at 90 °C for 24 hours. Upon completion of the reaction, the reaction was cooled to room temperature and nitrogen was passed through to remove residual ammonia, followed by the addition of a dioxane solution (1.9 mL) in 4N HCl. After stirring for 30 min, the reaction mixture was concentrated under reduced pressure to afford ethyl 3-amino-3-methylbutyrate hydrochloride as a gray solid (1.19 g, 84% yield).1H NMR (CDCl3, 400 MHz) δ ppm: 1.2 (t, 3H), 1.26 (s, 6H), 2.65 (s, 2H), 4.1 (q, 2H), 8.27 (br s, 3H).

References

[1] Journal of Medicinal Chemistry, 2009, vol. 52, # 2, p. 293 - 307
[2] Patent: WO2005/13986, 2005, A1. Location in patent: Page/Page column 36
[3] Patent: WO2005/14572, 2005, A1. Location in patent: Page/Page column 26; 27
[4] Patent: US2007/142414, 2007, A1. Location in patent: Page/Page column 17
[5] Patent: WO2008/20206, 2008, A2. Location in patent: Page/Page column 50

3-AMINO-3-METHYL-BUTYRIC ACID ETHYL ESTER HCL Preparation Products And Raw materials

Raw materials

Preparation Products

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3-AMINO-3-METHYL-BUTYRIC ACID ETHYL ESTER HCL Suppliers

J & K SCIENTIFIC LTD.
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View Lastest Price from 3-AMINO-3-METHYL-BUTYRIC ACID ETHYL ESTER HCL manufacturers

Career Henan Chemical Co
Product
3-AMINO-3-METHYL-BUTYRIC ACID ETHYL ESTER HCL 85532-40-7
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2020-01-02

85532-40-7, 3-AMINO-3-METHYL-BUTYRIC ACID ETHYL ESTER HCLRelated Search:


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