ChemicalBook > CAS DataBase List > 9H-INDENO[1,2-B]PYRAZINE-2,3-DICARBONITRILE, 9-[(PHENYLMETHOXY)IMINO]-

9H-INDENO[1,2-B]PYRAZINE-2,3-DICARBONITRILE, 9-[(PHENYLMETHOXY)IMINO]-

Product Name
9H-INDENO[1,2-B]PYRAZINE-2,3-DICARBONITRILE, 9-[(PHENYLMETHOXY)IMINO]-
CAS No.
924296-18-4
Chemical Name
9H-INDENO[1,2-B]PYRAZINE-2,3-DICARBONITRILE, 9-[(PHENYLMETHOXY)IMINO]-
Synonyms
DUB-IN-1;DUBs-IN-1;USP8-IN-22d;DUBs inhibitor 1;DUB-IN-1, 10 mM in DMSO;Deubiquitinase,DUBs,Inhibitor,DUBIN1,inhibit,DUB IN 1;9-Benzyloxyimino-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile;9-[(Phenylmethoxy)imino]-9H-Indeno[1,2-b]pyrazine-2,3-dicarbonitrile;9H-INDENO[1,2-B]PYRAZINE-2,3-DICARBONITRILE, 9-[(PHENYLMETHOXY)IMINO]-
CBNumber
CB42467854
Molecular Formula
C20H11N5O
Formula Weight
337.33
MOL File
924296-18-4.mol
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9H-INDENO[1,2-B]PYRAZINE-2,3-DICARBONITRILE, 9-[(PHENYLMETHOXY)IMINO]- Property

storage temp. 
Store at -20°C
solubility 
DMSO : 100 mg/mL (296.45 mM; Need ultrasonic)
form 
Powder
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-2849
Product name
DUB-IN-1
Purity
99.59%
Packaging
10mg
Price
$600
Updated
2021/12/16
Biorbyt Ltd
Product number
orb611805
Product name
USP8-IN-22d
Packaging
10mg
Price
$615.4
Updated
2021/12/16
ChemScene
Product number
CS-2849
Product name
DUB-IN-1
Purity
99.59%
Packaging
50mg
Price
$1800
Updated
2021/12/16
Biorbyt Ltd
Product number
orb611805
Product name
USP8-IN-22d
Packaging
50mg
Price
$1802
Updated
2021/12/16
Biorbyt Ltd
Product number
orb611805
Product name
USP8-IN-22d
Packaging
100mg
Price
$2512.6
Updated
2021/12/16
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9H-INDENO[1,2-B]PYRAZINE-2,3-DICARBONITRILE, 9-[(PHENYLMETHOXY)IMINO]- Chemical Properties,Usage,Production

Biological Activity

Potent and selective ubiquitin specific peptidase USP8 deubiquitinase (DUB) inhibitor.

DUB-IN-1 is a potent and selective ubiquitin specific peptidase USP8 deubiquitinase (DUB) inhibitor (IC50 = 850 nM/USP8, >100 μM/USP7). DUB-IN-1 inhibits the proliferation (200-800 nM for 24 or 48h; LN229, U87MG, and T98G cells), invasion (500-800 nM for 48 or 96h; LN229 and T98G cells), and stemness (500-800 nM for 7 or 14 days; LN229 and T98G cells) in GBM cultures.

9H-INDENO[1,2-B]PYRAZINE-2,3-DICARBONITRILE, 9-[(PHENYLMETHOXY)IMINO]- Preparation Products And Raw materials

Raw materials

Preparation Products

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9H-INDENO[1,2-B]PYRAZINE-2,3-DICARBONITRILE, 9-[(PHENYLMETHOXY)IMINO]- Suppliers

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924296-18-4, 9H-INDENO[1,2-B]PYRAZINE-2,3-DICARBONITRILE, 9-[(PHENYLMETHOXY)IMINO]-Related Search:


  • 9-[(Phenylmethoxy)imino]-9H-Indeno[1,2-b]pyrazine-2,3-dicarbonitrile
  • 9H-INDENO[1,2-B]PYRAZINE-2,3-DICARBONITRILE, 9-[(PHENYLMETHOXY)IMINO]-
  • DUBs inhibitor 1
  • DUBs-IN-1
  • 9-Benzyloxyimino-9H-indeno[1,2-b]pyrazine-2,3-dicarbonitrile
  • USP8-IN-22d
  • DUB-IN-1
  • Deubiquitinase,DUBs,Inhibitor,DUBIN1,inhibit,DUB IN 1
  • DUB-IN-1, 10 mM in DMSO
  • 924296-18-4