ChemicalBook > CAS DataBase List > 7-bromo-4,4-dimethyl-1H-benzo[d][1,3]oxazin-2(4H)-one

7-bromo-4,4-dimethyl-1H-benzo[d][1,3]oxazin-2(4H)-one

Product Name
7-bromo-4,4-dimethyl-1H-benzo[d][1,3]oxazin-2(4H)-one
CAS No.
1245643-21-3
Chemical Name
7-bromo-4,4-dimethyl-1H-benzo[d][1,3]oxazin-2(4H)-one
Synonyms
7-bromo-4,4-dimethyl-1H-3,1-benzoxazin-2-one;7-Bromo-4,4-dimethyl-1H-benzo[d][1,3]oxazin-2(4H);7-bromo-4,4-dimethyl-1H-benzo[d][1,3]oxazin-2(4H)-one;7-Bromo-1,4-dihydro-4,4-dimethyl-2H-3,1-benzoxazin-2-one;2H-3,1-Benzoxazin-2-one, 7-bromo-1,4-dihydro-4,4-dimethyl-
CBNumber
CB42470515
Molecular Formula
C10H10BrNO2
Formula Weight
256.1
MOL File
1245643-21-3.mol
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7-bromo-4,4-dimethyl-1H-benzo[d][1,3]oxazin-2(4H)-one Property

Boiling point:
258℃
Density 
1.468
Flash point:
110℃
storage temp. 
Sealed in dry,Room Temperature
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
B998303
Product name
7-Bromo-4,4-dimethyl-1H-benzo[d][1,3]oxazin-2(4H)-one
Packaging
100mg
Price
$240
Updated
2021/12/16
AK Scientific
Product number
8528DG
Product name
7-Bromo-4,4-dimethyl-1H-benzo[d][1,3]oxazin-2(4H)-one
Packaging
50mg
Price
$205
Updated
2021/12/16
AK Scientific
Product number
8528DG
Product name
7-Bromo-4,4-dimethyl-1H-benzo[d][1,3]oxazin-2(4H)-one
Packaging
100mg
Price
$254
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0316073
Product name
7-BROMO-4,4-DIMETHYL-1H-BENZO[D][1,3]OXAZIN-2(4H)-ONE
Purity
95.00%
Packaging
5MG
Price
$497.93
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0316073
Product name
7-BROMO-4,4-DIMETHYL-1H-BENZO[D][1,3]OXAZIN-2(4H)-ONE
Purity
95.00%
Packaging
1G
Price
$2250
Updated
2021/12/16
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7-bromo-4,4-dimethyl-1H-benzo[d][1,3]oxazin-2(4H)-one Chemical Properties,Usage,Production

Synthesis

1451389-06-2

530-62-1

1245643-21-3

Step 2: To a solution of 2-(2-amino-4-bromophenyl)propan-2-ol (2.3 g, 10.0 mmol) in tetrahydrofuran (THF, 50 mL) was added N,N'-carbonyl diimidazole (CDI, 1.95 g, 12.0 mmol) at room temperature. The reaction mixture was slowly warmed to 60 °C and the reaction was stirred at this temperature overnight. After completion of the reaction, the solvent was removed by rotary evaporator. The residue was dissolved in ethyl acetate (50 mL) and washed sequentially with 1M aqueous hydrochloric acid (20 mL x 2) and saturated saline (20 mL x 2). The organic phase was dried with anhydrous sodium sulfate, filtered and concentrated. The resulting crude product was recrystallized by mixed solvent recrystallization of dichloromethane (DCM) and hexane to afford 7-bromo-4,4-dimethyl-1H-benzo[d][1,3]oxazin-2(4H)-one (2.3 g, 7.37% yield) as a white solid.

References

[1] Patent: WO2013/124026, 2013, A1. Location in patent: Page/Page column 173
[2] Patent: KR2016/37198, 2016, A. Location in patent: Paragraph 3363-3364; 3367

7-bromo-4,4-dimethyl-1H-benzo[d][1,3]oxazin-2(4H)-one Preparation Products And Raw materials

Raw materials

Preparation Products

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7-bromo-4,4-dimethyl-1H-benzo[d][1,3]oxazin-2(4H)-one Suppliers

China 26 India 1 United Kingdom 1 United States 4 Global 32
Shanghai Boc Chemical Co.,Ltd
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Bide Pharmatech Ltd.
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Porse Fine Chemical Co.,LTD
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20-66003216 18666003216
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+86-20-28069063
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info@porsefinechemical.com
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China
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Amadis Chemical Company Limited
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Taian Jiaye Biotechnology Co.Ltd
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Sichuan BaiPeng Biotechnology Co., Ltd.
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Aikon International Limited
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Suzhou Nuoouman Biological Technology Co., Ltd.
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1245643-21-3, 7-bromo-4,4-dimethyl-1H-benzo[d][1,3]oxazin-2(4H)-oneRelated Search:


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  • 7-Bromo-4,4-dimethyl-1H-benzo[d][1,3]oxazin-2(4H)
  • 2H-3,1-Benzoxazin-2-one, 7-bromo-1,4-dihydro-4,4-dimethyl-
  • 7-bromo-4,4-dimethyl-1H-3,1-benzoxazin-2-one
  • 1245643-21-3
  • C10H10NO2Br