Thiazolo[4,5-c]pyridine-2-thiol
- Product Name
- Thiazolo[4,5-c]pyridine-2-thiol
- CAS No.
- 65128-66-7
- Chemical Name
- Thiazolo[4,5-c]pyridine-2-thiol
- Synonyms
- Thiazolo[4,5-c]pyridine-2-thiol;[1,3]thiazolo[4,5-c]pyridine-2-thiol;Thiazolo[4,5-c]pyridine-2(3H)-thione
- CBNumber
- CB42471547
- Molecular Formula
- C6H4N2S2
- Formula Weight
- 168.24
- MOL File
- 65128-66-7.mol
Thiazolo[4,5-c]pyridine-2-thiol Property
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 7941CV
- Product name
- Thiazolo[4,5-c]pyridine-2-thiol
- Packaging
- 250mg
- Price
- $332
- Updated
- 2021/12/16
- Product number
- 7941CV
- Product name
- Thiazolo[4,5-c]pyridine-2-thiol
- Packaging
- 5g
- Price
- $1772
- Updated
- 2021/12/16
- Product number
- 65128667
- Product name
- Thiazolo[4,5-c]pyridine-2(3H)-thione
- Packaging
- 1g
- Price
- $208
- Updated
- 2021/12/16
- Product number
- CD11079234
- Product name
- Thiazolo[4,5-c]pyridine-2(3H)-thione
- Purity
- 95+%
- Packaging
- 1g
- Price
- $530
- Updated
- 2021/12/16
- Product number
- 65128667
- Product name
- Thiazolo[4,5-c]pyridine-2(3H)-thione
- Packaging
- 5g
- Price
- $624
- Updated
- 2021/12/16
Thiazolo[4,5-c]pyridine-2-thiol Chemical Properties,Usage,Production
Synthesis
20511-15-3
140-89-6
65128-66-7
Synthesis of thiazolo[4,5-c]pyridine-2-thiol (68): 3-amino-4-chloropyridine (67, 1.0 g, 8.3 mmol) was dissolved in 15 mL of anhydrous N,N-dimethylformamide (DMF) under nitrogen protection. Potassium ethylxanthate (KSCSOEt, 2.0 g, 12.5 mmol) was added to this solution in batches. The reaction mixture was stirred at 95-100°C for 15 h. The progress of the reaction was monitored by thin layer chromatography (TLC, unfolding agent: 70% ethyl acetate/hexane) to confirm complete consumption of the raw material. Upon completion of the reaction, the reaction was quenched with 35 mL of ice water followed by the addition of 40 mL of 1 M hydrochloric acid (HCl). The mixture was continued to be stirred for 30 minutes, during which time a precipitate was generated. The precipitate was collected by filtration, washed with 250 mL of water and dried under vacuum over phosphorus pentoxide (P4O10) to afford the target product thiazolo[4,5-c]pyridine-2-thiol (68, 0.98 g, 70% yield).
References
[1] Patent: WO2006/122156, 2006, A2. Location in patent: Page/Page column 145-146
[2] Advanced Synthesis and Catalysis, 2017, vol. 359, # 11, p. 1837 - 1843
Thiazolo[4,5-c]pyridine-2-thiol Preparation Products And Raw materials
Raw materials
Preparation Products
Thiazolo[4,5-c]pyridine-2-thiol Suppliers
- Tel
- 021-60343070
- Fax
- 021-35122006
- Country
- China
- ProdList
- 12740
- Advantage
- 55
- Tel
- 13675155016
- Fax
- 18912765016
- tongtf110@sina.com
- Country
- China
- ProdList
- 963
- Advantage
- 55
- Tel
- 028-65791793 18140026355
- Fax
- QQ568470422
- 568470422@qq.com
- Country
- China
- ProdList
- 9997
- Advantage
- 58
- Tel
- 025-66113011 13155353615
- Fax
- (7)02557626880
- qzhang@aikonchem.com
- Country
- China
- ProdList
- 15394
- Advantage
- 58
- Tel
- 15026866316
- 180642609@qq.com
- Country
- China
- ProdList
- 4967
- Advantage
- 58
- Tel
- 18201727566
- Fax
- QQ:230497258
- 230497258@qq.com
- Country
- China
- ProdList
- 513
- Advantage
- 58
- Tel
- 021-51816796-820 13611835272
- Fax
- 021-5161 3951
- sales2@sunwaypharm.com
- Country
- China
- ProdList
- 44119
- Advantage
- 58
- Tel
- 183-0212-4410 18302124410
- Djt18302124410@163.com
- Country
- China
- ProdList
- 3000
- Advantage
- 58
- Tel
- 2383948258 19172820304
- 2383948258@qq.com
- Country
- China
- ProdList
- 12987
- Advantage
- 58
- Tel
- 010-60605840 15801484223;
- psaitong@jm-bio.com
- Country
- China
- ProdList
- 29757
- Advantage
- 58