ChemicalBook > CAS DataBase List > Phosphonium, (2-methoxyethyl)triphenyl-, bromide

Phosphonium, (2-methoxyethyl)triphenyl-, bromide

Product Name: Phosphonium, (2-methoxyethyl)triphenyl-, bromide
CAS No.: 55894-16-1
Chemical Name: Phosphonium, (2-methoxyethyl)triphenyl-, bromide
Synonyms: Nsc280056;Triprolidine Impurity 3;(2-Methoxyethyl)triphenyl;(2-Methoxyethyl)(triphenyl)phosphoniuM;METHOXYETHYLTRIPHENYLPHOSPHONIUM BROMIDE;(2-Methoxyethyl)triphenylphosphoniuM broMide;Phosphonium, (2-methoxyethyl)triphenyl-, bromide;(2-methoxyethyl)triphenyl-Phosphonium bromide (1:1);Phosphonium, (2-methoxyethyl)triphenyl-, bromide (1:1);(2-METHOXY-ETHYL)-TRIPHENYL-PHOSPHONIUM, BROMIDE
CBNumber: CB42495455
Molecular Formula: C21H22BrOP
Formula Weight: 401.276541
MOL File: 55894-16-1.mol

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Phosphonium, (2-methoxyethyl)triphenyl-, bromide Property

Melting point:: 216 °C
storage temp.: Inert atmosphere,Room Temperature
Appearance: White to off-white Solid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S80846
Product name: (2-METHOXY-ETHYL)-TRIPHENYL-PHOSPHONIUM, BROMIDE
Purity: AldrichCPR
Packaging: 1 unit
Price: $113
Updated: 2025/07/31

Sigma-Aldrich

Product number: S80846
Product name: (2-METHOXY-ETHYL)-TRIPHENYL-PHOSPHONIUM, BROMIDE
Purity: Aldrich
Packaging: 250mg
Price: $110
Updated: 2024/03/01

Ark Pharm

Product number: AK102809
Product name: (2-METHOXY-ETHYL)-TRIPHENYL-PHOSPHONIUM, BROMIDE
Purity: 97%
Packaging: 10g
Price: $121
Updated: 2021/12/16

Matrix Scientific

Product number: 095881
Product name: (2-Methoxyethyl)triphenylphosphonium bromide
Purity: 95+%
Packaging: 5g
Price: $252
Updated: 2021/12/16

AK Scientific

Product number: Y5043
Product name: Methoxyethyltriphenylphosphoniumbromide
Packaging: 1g
Price: $85
Updated: 2021/12/16

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Phosphonium, (2-methoxyethyl)triphenyl-, bromide Chemical Properties,Usage,Production

Uses

(2-Methoxyethyl)triphenylphosphonium Bromide is an intermediate for the synthesis of (Z)-Triprolidine Oxalate Salt (T814007), which is an antihistaminic agent with anticholinergic properties. Triprolidine is used to treat and prevent symptoms associated with allergies. Triprolidine is also used in combination with cold medicine to provide relief for flu-like symptoms.

Synthesis

603-35-0

6482-24-2

55894-16-1

a) Triphenylphosphine (300 g, 1.14 mol) and 2-bromoethyl methyl ether (200 g, 1.43 mol) were refluxed in toluene (1 L) for 24 hours. Upon completion of the reaction, the reaction mixture was cooled to 30 °C and filtered to afford (2-methoxyethyl)triphenylphosphonium bromide (450 g, 78%). Subsequently, the product (450 g) was reacted with pyrrolidine (96 g, 1.37 mol) in methanol (500 mL) at 60°C for 2 hours. At the end of the reaction, methanol was removed by distillation and the resulting solid was suspended in toluene (appropriate amount), cooled to 30°C and filtered to give 2-(1-pyrrolidinyl)ethyltriphenylphosphonium bromide (450 g, 91%).NMR (D2O) δ: 1.67 (m, 4H), 2.46 (m, 4H), 2.78 (m, 2H), 3.41 (m, 2H), 7.68 ( m, 15H).

References

[1] Tetrahedron Letters, 2008, vol. 49, # 5, p. 824 - 826
[2] Patent: WO2007/141803, 2007, A2. Location in patent: Page/Page column 5-6

Phosphonium, (2-methoxyethyl)triphenyl-, bromide Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Phosphonium, (2-methoxyethyl)triphenyl-, bromide manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: (2-Methoxyethyl)(triphenyl)phosphonium 55894-16-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 30tons/month
Release date: 2025-05-07

Henan Aochuang Chemical Co.,Ltd.

Product: Phosphonium, (2-methoxyethyl)triphenyl-, bromide 55894-16-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1ton
Release date: 2022-09-30

Longyan Tianhua Biological Technology Co., Ltd

Product: Phosphonium, (2-methoxyethyl)triphenyl-, bromide 55894-16-1
Price: US $20.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10000KG
Release date: 2020-11-10

55894-16-1, Phosphonium, (2-methoxyethyl)triphenyl-, bromideRelated Search:

1-(pyridin-2-yl)-1-(p-tolyl)ethan-1-ol Pyridine, 2-[(1E)-1-(4-methylphenyl)-3-(1-oxido-1-pyrrolidinyl)-1-propen-1-yl]- Triprolidine Hydrochloride Z-IsoMer 3-(pyrrolidin-1-yl)-1-(p-tolyl)propan-1-one alpha-[2-(1-pyrrolidinyl)ethyl]-alpha-(p-tolyl)pyridine-2-methanol ISOPROPYLTRIPHENYLPHOSPHONIUM IODIDE (CYANOMETHYL)TRIPHENYLPHOSPHONIUM BROMIDE (4-BROMOBENZYL)TRIPHENYLPHOSPHONIUM BROMIDE (3-BROMOPROPYL)TRIPHENYLPHOSPHONIUM BROMIDE CYANOMETHYLTRI-N-BUTYLPHOSPHONIUM CHLORIDE IODOMETHYL-TRIPHENYL-PHOSPHONIUM IODIDE (CYANOMETHYL)TRIPHENYLPHOSPHONIUM CHLORIDE

Nsc280056

Phosphonium, (2-methoxyethyl)triphenyl-, bromide

(2-Methoxyethyl)triphenylphosphoniuM broMide

(2-Methoxyethyl)(triphenyl)phosphoniuM

Phosphonium, (2-methoxyethyl)triphenyl-, bromide (1:1)

(2-Methoxyethyl)triphenyl

Triprolidine Impurity 3

METHOXYETHYLTRIPHENYLPHOSPHONIUM BROMIDE

(2-METHOXY-ETHYL)-TRIPHENYL-PHOSPHONIUM, BROMIDE

(2-methoxyethyl)triphenyl-Phosphonium bromide (1:1)

55894-16-1

C21H22BrOP