ChemicalBook > CAS DataBase List > orvepitant
orvepitant
- Product Name
- orvepitant
- CAS No.
- 579475-18-6
- Chemical Name
- orvepitant
- Synonyms
- Orvepitat;orvepitan;orvepitant;(2R,4S)-N-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethyl)-2-(4-fluoro-2-methylphenyl)-N-methyl-4;1-Piperidinecarboxamide, N-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl]-2-(4-fluoro-2-methylphenyl)-4-[(8aS)-hexahydro-6-oxopyrrolo[1,2-a]pyrazin-2(1H)-yl]-N-methyl-, (2R,4S)-
- CBNumber
- CB42498830
- Molecular Formula
- C31H35F7N4O2
- Formula Weight
- 628.62
- MOL File
- 579475-18-6.mol
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orvepitant Property
- Boiling point:
- 627.5±55.0 °C(Predicted)
- Density
- 1.37±0.1 g/cm3(Predicted)
- pka
- 8.89±0.20(Predicted)
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orvepitant Chemical Properties,Usage,Production
Uses
Orvepitant (GW823296) is a compound with the ability to inhibit pruritus induced by cancer epidermal growth factor receptor inhibitor (EGFRI) and is a neurokinin-1 receptor antagonist.
References
[1] Neurokinin-1 antagonist orvepitant for EGFRI-induced pruritus in patients with cancer: a randomised, placebo-controlled phase II trial DOI:10.1136/bmjopen-2019-030114
orvepitant Preparation Products And Raw materials
Raw materials
Preparation Products
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orvepitant Suppliers
- Tel
- 028-83379370 13880556291
- Fax
- 028-87747383
- tcy@tcypharm.com
- Country
- China
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- Tel
- 010-88886666-01 13112345678
- Fax
- CDXH21@126.com
- loyson@tcypharm.com
- Country
- China
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- Tel
- 4008200310
- marketing@tsbiochem.com
- Country
- China
- ProdList
- 24961
- Advantage
- 58