(1-methyl-1H-indazol-4-yl)methanol

Product Name: (1-methyl-1H-indazol-4-yl)methanol
CAS No.: 1092961-12-0
Chemical Name: (1-methyl-1H-indazol-4-yl)methanol
Synonyms: 1-Methyl-1H-indazol-4-methanol;1-Methyl-1H-indazole-4-methanol;1H-Indazole-4-methanol, 1-methyl-;(1-methyl-1H-indazol-4-yl)methanol;4-(Hydroxymethyl)-1-methyl-1H-indazole;4-(Hydroxymethyl)-1-methyl-1H-indazole 97%
CBNumber: CB42500306
Molecular Formula: C9H10N2O
Formula Weight: 162.19
MOL File: 1092961-12-0.mol

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(1-methyl-1H-indazol-4-yl)methanol Property

storage temp.: Sealed in dry,Room Temperature
form: solid
Appearance: White to off-white Solid

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Safety

HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHB00058
Product name: 4-(Hydroxymethyl)-1-methyl-1H-indazole
Purity: AldrichCPR
Packaging: 1G
Price: $403
Updated: 2025/07/31

American Custom Chemicals Corporation

Product number: CHM0385479
Product name: (1-METHYL-1H-INDAZOL-4-YL)METHANOL
Purity: 95.00%
Packaging: 5MG
Price: $498.23
Updated: 2021/12/16

AK Scientific

Product number: Y5195
Product name: (1-Methyl-1H-indazol-4-yl)methanol
Packaging: 5g
Price: $797
Updated: 2021/12/16

Apolloscientific

Product number: OR30861
Product name: 4-(Hydroxymethyl)-1-methyl-1H-indazole
Packaging: 250mg
Price: $96
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H01-1-4Q
Product name: 4-(Hydroxymethyl)-1-methyl-1H-indazole
Packaging: 250mg
Price: $125
Updated: 2021/12/16

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(1-methyl-1H-indazol-4-yl)methanol Chemical Properties,Usage,Production

Synthesis

1053655-56-3

1092961-12-0

General procedure for the synthesis of (1-methyl-1H-indazol-4-yl)methanol from 1-methyl-1H-indazole-4-carboxaldehyde: To a solution of 1-methyl-1H-indazole-4-carboxaldehyde (180 mg, 1.12 mmol) in tetrahydrofuran (THF, 10 mL) was added sodium borohydride (NaBH4, 85 mg, 2.24 mmol) in batches at room temperature. The reaction mixture was stirred at room temperature for 1 hour. After completion of the reaction, it was acidified to pH 3 with dilute hydrochloric acid and extracted with ethyl acetate (EtOAc). The organic layers were combined, washed sequentially with saturated sodium bicarbonate solution and brine, dried over anhydrous sodium sulfate (Na2SO4), filtered and concentrated under reduced pressure to afford the crude product (1-methyl-1H-indazol-4-yl)methanol (191 mg), which could be used for the next reaction without further purification.

References

[1] Patent: WO2013/102142, 2013, A1. Location in patent: Paragraph 0159
[2] Patent: WO2013/102145, 2013, A1. Location in patent: Paragraph 0213
[3] Patent: US2015/344483, 2015, A1. Location in patent: Paragraph 0416; 0417

(1-methyl-1H-indazol-4-yl)methanol Preparation Products And Raw materials

Raw materials

Preparation Products

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(1-methyl-1H-indazol-4-yl)methanol Suppliers

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1092961-12-0