1H-BENZIMIDAZOLE-2-SULFONIC ACID Property

Melting point:

116-119 °C(lit.)

Density 

1.4876 (rough estimate)

refractive index 

1.6000 (estimate)

storage temp. 

2-8°C

solubility 

DMSO (Slightly), Methanol (Slightly)

form 

Solid

pka

-1.47±0.40(Predicted)

color 

Off-White to Pale Beige

CAS DataBase Reference

40828-54-4(CAS DataBase Reference)

Safety

Hazard Codes 

C

Risk Statements 

34

Safety Statements 

26-36/37/39-45

RIDADR 

UN 3261 8/PG 2

WGK Germany 

3

HazardClass 

IRRITANT

HS Code 

2933998090

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

1H-BENZIMIDAZOLE-2-SULFONIC ACID Chemical Properties,Usage,Production

Chemical Properties

white to light beige crystalline powder

Uses

Benzimidazole 2-Sulfonic Acid is a versatile reactant used in the preparation of bis(benzimidazol-2-yl)amines with antitrichinellosis activity.

General Description

1H-Benzimidazole-2-sulfonic acid (BISA) is a glutamate racemase (GR) inhibitor. It is a promising candidate for developing antibacterial drugs. BISA can be prepared by the oxidation of 1H-benzimidazole-2-thiol using hydrogen peroxide in the presence of potassium hydroxide.