5-bromo-1,3-dimethyl-1H-indazole
- Product Name
- 5-bromo-1,3-dimethyl-1H-indazole
- CAS No.
- 552331-30-3
- Chemical Name
- 5-bromo-1,3-dimethyl-1H-indazole
- Synonyms
- 5-BroMo-1,3-diMethylindaz...;5-Bromo-1,3-dimethylindazole;5-bromo-1,3-dimethyl-1H-indazole;1H-Indazole, 5-bromo-1,3-dimethyl-;3-Methyl-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzo[d]oxazol-2(3H)-one
- CBNumber
- CB42504526
- Molecular Formula
- C9H9BrN2
- Formula Weight
- 225.09
- MOL File
- 552331-30-3.mol
5-bromo-1,3-dimethyl-1H-indazole Property
- storage temp.
- 2-8°C
- Appearance
- Off-white to light yellow Solid
Safety
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B691628
- Product name
- 5-Bromo-1,3-dimethylindazole
- Packaging
- 50mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- B691628
- Product name
- 5-Bromo-1,3-dimethylindazole
- Packaging
- 100mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- 112335
- Product name
- 5-Bromo-1,3-dimethylindazole
- Packaging
- 1g
- Price
- $109
- Updated
- 2021/12/16
- Product number
- 3H32-9-4M
- Product name
- 5-Bromo-1,3-dimethyl-1H-indazole
- Packaging
- 250mg
- Price
- $134
- Updated
- 2021/12/16
- Product number
- Y5468
- Product name
- 5-Bromo-1,3-dimethyl-1H-indazole
- Packaging
- 1g
- Price
- $197
- Updated
- 2021/12/16
5-bromo-1,3-dimethyl-1H-indazole Chemical Properties,Usage,Production
Synthesis
552331-16-5
74-88-4
552331-30-3
Example 112A Synthesis of 5-bromo-1,3-dimethyl-1H-indazole: 5-bromo-3-methyl-1H-indazole (500 mg; 2.37 mmol) was added to a suspension of 60% sodium hydride (115 mg; 2.84 mmol) in N,N-dimethylformamide (10 mL). After stirring for 15 min at room temperature, iodomethane (456 mg; 3.21 mmol) was added and the reaction was continued with stirring for 2 hours. Upon completion of the reaction, the reaction mixture was diluted with water and extracted with ethyl acetate. The organic phases were combined, washed sequentially with water and saturated brine, and dried over anhydrous magnesium sulfate. The organic phases were concentrated under reduced pressure and the resulting crude product was purified by fast column chromatography (eluent: ether/hexane=1:1) to afford the target compound 5-bromo-1,3-dimethyl-1H-indazole (360 mg; 67% yield).
References
[1] Bioorganic and Medicinal Chemistry, 2006, vol. 14, # 20, p. 6832 - 6846
[2] Patent: US2003/187026, 2003, A1
[3] Patent: US2003/199511, 2003, A1. Location in patent: Page/Page column 41
[4] Patent: WO2017/55305, 2017, A1. Location in patent: Page/Page column 53
[5] Bioorganic and Medicinal Chemistry, 2016, vol. 24, # 11, p. 2504 - 2518
5-bromo-1,3-dimethyl-1H-indazole Preparation Products And Raw materials
Raw materials
Preparation Products
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