ChemicalBook > CAS DataBase List > 4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylicacid, 5,6-dihydro-8-hydroxy-5-methyl-6-oxo-, ethyl ester

4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylicacid, 5,6-dihydro-8-hydroxy-5-methyl-6-oxo-, ethyl ester

Product Name
4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylicacid, 5,6-dihydro-8-hydroxy-5-methyl-6-oxo-, ethyl ester
CAS No.
131666-45-0
Chemical Name
4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylicacid, 5,6-dihydro-8-hydroxy-5-methyl-6-oxo-, ethyl ester
Synonyms
Flumazenil EP Impurity B;FlumazenilEPImpurityB-d3;Flumazenil impurity B CRS;Flumazenil impurity B (EP);Defluoro 8-Hydroxy Flumazenil;Flumazenil USP Related Compound B;Defluoro 8-Hydroxy FluMazenil (IMpurity);Flumazenil Impurity 2(Flumazenil EP Impurity B);4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylicacid, 5,6-d...;Ethyl8-hydroxy-5-methyl-6-oxo-4H-imidazol1,5-A1,4benzodiazepine-3-carboxylate
CBNumber
CB42505664
Molecular Formula
C15H15N3O4
Formula Weight
301.3
MOL File
131666-45-0.mol
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4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylicacid, 5,6-dihydro-8-hydroxy-5-methyl-6-oxo-, ethyl ester Property

Boiling point:
588.6±50.0 °C(Predicted)
Density 
1.42±0.1 g/cm3(Predicted)
pka
8.54±0.20(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P313Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
Y0000335
Product name
Flumazenil impurity B
Purity
European Pharmacopoeia (EP) Reference Standard
Packaging
y0000335
Price
$153
Updated
2024/03/01
Sigma-Aldrich
Product number
1273820
Product name
Flumazenil impurity B
Packaging
20mg
Price
$1780
Updated
2024/03/01
TRC
Product number
D228740
Product name
Defluoro8-HydroxyFlumazenil(Impurity)
Packaging
2.5mg
Price
$160
Updated
2021/12/16
AK Scientific
Product number
6319DT
Product name
Ethyl8-hydroxy-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate
Packaging
5mg
Price
$329
Updated
2021/12/16
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4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylicacid, 5,6-dihydro-8-hydroxy-5-methyl-6-oxo-, ethyl ester Chemical Properties,Usage,Production

Uses

Defluoro 8-hydroxy Flumazenil is an impurity of Flumazenil (F500450), a benzodiazepine antagonist that can prevent or abolish (at the receptor level) the effects of a benzodiazepine.

4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylicacid, 5,6-dihydro-8-hydroxy-5-methyl-6-oxo-, ethyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylicacid, 5,6-dihydro-8-hydroxy-5-methyl-6-oxo-, ethyl ester Suppliers

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131666-45-0, 4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylicacid, 5,6-dihydro-8-hydroxy-5-methyl-6-oxo-, ethyl esterRelated Search:

Ro 15-3505 7-Fluoro-3,4-dihydro-4-methyl-1H-1,4-benzodiazepine-2,5-dione N,N-Dimethyformamide diethy acetal 4H-IMIDAZO[1,5-A][1,4]BENZODIAZEPINE-3-CARBOXYLIC ACID, 8-FLUORO-5,6-DIHYDRO-5-METHYL-6-OXO- Flumazenil Ro 14-7437

  • 4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylicacid, 5,6-dihydro-8-hydroxy-5-methyl-6-oxo-, ethyl ester
  • Defluoro 8-Hydroxy FluMazenil (IMpurity)
  • Ethyl 8-hydroxy-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carboxylate
  • Flumazenil EP Impurity B
  • Flumazenil impurity B (EP)
  • Flumazenil Impurity 2(Flumazenil EP Impurity B)
  • Flumazenil impurity B CRS
  • Ethyl 8-hydroxy-5-methyl-6-oxo-5,6-dihydro-4H-benzo[f]imidazo[1,5-a][1,4]diazepine-3-carboxylate
  • 4H-Imidazo[1,5-a][1,4]benzodiazepine-3-carboxylicacid, 5,6-d...
  • Defluoro 8-Hydroxy Flumazenil
  • FlumazenilEPImpurityB-d3
  • Flumazenil USP Related Compound B
  • Ethyl8-hydroxy-5-methyl-6-oxo-4H-imidazol1,5-A1,4benzodiazepine-3-carboxylate
  • 131666-45-0