Guvacoline Hydrobromide
- Product Name
- Guvacoline Hydrobromide
- CAS No.
- 17210-51-4
- Chemical Name
- Guvacoline Hydrobromide
- Synonyms
- 1,2,5,6-Tetrahydro-3-pyridinecarboxylic Acid Methyl Ester HydrobroMide;1,2,5,6-tetrahydro-3-pyridinecarboxylic acid, methyl ester, monohydrobromide
- CBNumber
- CB42509354
- Molecular Formula
- C7H12BrNO2
- Formula Weight
- 222.07968
- MOL File
- 17210-51-4.mol
Guvacoline Hydrobromide Property
- Melting point:
- 144°C
- storage temp.
- -20°C Freezer
- solubility
- ≤1mg/ml in DMSO;1mg/ml in dimethyl formamide
- form
- crystalline solid
- InChI
- InChI=1S/C7H11NO2.BrH/c1-10-7(9)6-3-2-4-8-5-6;/h3,8H,2,4-5H2,1H3;1H
- InChIKey
- DOXOETUWVNVADB-UHFFFAOYSA-N
- SMILES
- C1C=C(C(OC)=O)CNC1.Br
N-Bromosuccinimide Price
- Product number
- 17190
- Product name
- Guvacoline (hydrobromide)
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $44
- Updated
- 2024/03/01
- Product number
- 17190
- Product name
- Guvacoline (hydrobromide)
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $161
- Updated
- 2024/03/01
- Product number
- 17190
- Product name
- Guvacoline (hydrobromide)
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $299
- Updated
- 2024/03/01
- Product number
- G876500
- Product name
- GuvacolineHydrobromide
- Packaging
- 50mg
- Price
- $790
- Updated
- 2021/12/16
- Product number
- 9776CV
- Product name
- GuvacolineHydrobromide
- Packaging
- 1mg
- Price
- $147
- Updated
- 2021/12/16
Guvacoline Hydrobromide Chemical Properties,Usage,Production
Chemical Properties
Crystalline Solid
Uses
A muscarinic receptor used as nootropic agent.
Biological Activity
guvacoline is a kind of natural alkaloid which is found in areca nuts that is related to the nootropic, arecoline. guvacoline can function as a full agonist of atrial and ileal muscarinic receptors.in vitro: in human buccal epithelial cells, guvacoline could significantly decrease the colony-formation efficiency in a dose dependent manner, with the ic50 value of 2.1 mm. besides, guvacoline could also dose-dependently reduce the amount of total free low-molecular-weight thiols (0.88 mm guvacoline caused 25% decrease) and increase the number of single strand breaks [1].
target
atrial and ileal muscarinic receptors
IC 50
2.1 mm for growth inhibition of human buccal epithelial cells
References
[1] k. sundqvist, y. liu, j. nair, et al. cytotoxic and genotoxic effects of areca nut-related compounds in cultured human buccal epithelial cells. cancer research 49(19), 5294-5298 (1989).
Guvacoline Hydrobromide Preparation Products And Raw materials
Raw materials
Preparation Products
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