Ropivacaine-d7 Hydrochloride

Product Name: Ropivacaine-d7 Hydrochloride
CAS No.: 1217667-10-1
Chemical Name: Ropivacaine-d7 Hydrochloride
Synonyms: [2H7]-Ropivacaine HCl;Ropivacaine-d7 Hydrochloride;D7-(-)-Ropivacaine Hydrochloride;(–)-Ropivacaine-d7 hydrochloride;(2S)-N-(2,6-dimethylphenyl)-1-(1,1,2,2,3,3,3-heptadeuteriopropyl)piperidine-2-carboxamide:hydrochloride
CBNumber: CB42511508
Molecular Formula: C17H27ClN2O
Formula Weight: 310.87
MOL File: 1217667-10-1.mol

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Ropivacaine-d7 Hydrochloride Property

Melting point:: >245°C (dec.)
storage temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility: DMSO (Slightly), Methanol (Sparingly), Water (Slightly)
form: Solid
color: White to Off-White
Water Solubility: Water: soluble
Stability:: Hygroscopic

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 26495
Product name: (–)-Ropivacaine-d7 (hydrochloride)
Packaging: 500μg
Price: $110
Updated: 2024/03/01

Cayman Chemical

Product number: 26495
Product name: (–)-Ropivacaine-d7 (hydrochloride)
Packaging: 1mg
Price: $198
Updated: 2024/03/01

TRC

Product number: R675002
Product name: Ropivacaine-d7Hydrochloride
Packaging: 1mg
Price: $160
Updated: 2021/12/16

Usbiological

Product number: 020730
Product name: Ropivacaine-d7 Hydrochloride
Packaging: 1mg
Price: $446
Updated: 2021/12/16

AK Scientific

Product number: 7843DG
Product name: Ropivacaine-d7Hydrochloride
Packaging: 1mg
Price: $472
Updated: 2021/12/16

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Ropivacaine-d7 Hydrochloride Chemical Properties,Usage,Production

Description

(–)-Ropivacaine-d₇ is intended for use as an internal standard for the quantification of (–)-ropivacaine by GC- or LC-MS. (–)-Ropivacaine is a potent and reversible blocker of sodium channels in nerve fibers. In vivo, (–)-ropivacaine induces complete impairment of proprioception, motor function, and nociception in the hindleg of rats when 100 μL of an 8 mM solution is injected percutaneously into the sciatic nerve. (–)-Ropivacaine depresses myocardial contractile force in isolated rat hearts less potently than (±)-ropivacaine, as well as (–)- and (±)-bupivacaine . Formulations containing (–)-ropivacaine have been used as local anesthetics during surgery and childbirth.

Chemical Properties

White Solid

Uses

Labelled Ropivacaine (R675000). Anesthetic (local).

References

[1] HANSEN T G. Ropivacaine: a pharmacological review.[J]. Expert Review of Neurotherapeutics, 2004, 4 5: 781-791. DOI: 10.1586/14737175.4.5.781
[2] CATHERINE J SINNOTT B.A. Gary R S Ph D. Levobupivacaine versus ropivacaine for sciatic nerve block in the rat[J]. Regional Anesthesia and Pain Medicine, 2003, 28 4: Pages 294-303. DOI: 10.1016/s1098-7339(03)00188-3
[3] MATHEUS FéCCHIO PINOTTI. Myocardial contractility impairment with racemic bupivacaine, non-racemic bupivacaine and ropivacaine. A comparative study.[J]. Acta cirurgica brasileira, 2015, 30 7: 484-490. DOI: 10.1590/s0102-865020150070000006

Ropivacaine-d7 Hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Ropivacaine-d7 Hydrochloride Suppliers

Canada 1 China 19 India 3 United States 2 Global 25

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
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Chemsky（shanghai）International Co.,Ltd.

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Shanghai EFE Biological Technology Co., Ltd.

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Shenzhen Polymeri Biochemical Technology Co., Ltd.

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ChemeGen(Shanghai) Biotechnology Co.,Ltd.

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Energy Chemical

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LGC Science (Shanghai) Ltd.

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CHINA ISOTOPE CO., LIMITED

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Nanjing Shizhou Biology Technology Co.,Ltd

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Cayman Chemical Company

Tel: 800-364-9897
Email: sales@caymanchem.com
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1217667-10-1, Ropivacaine-d7 HydrochlorideRelated Search:

(2S)-N-(2,6-dimethylphenyl)-1-(1,1,2,2,3,3,3-heptadeuteriopropyl)piperidine-2-carboxamide:hydrochloride

Ropivacaine-d7 Hydrochloride

[2H7]-Ropivacaine HCl

(–)-Ropivacaine-d7 hydrochloride

D7-(-)-Ropivacaine Hydrochloride

1217667-10-1

C17H20D7ClN2O

Chiral Reagents

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Isotope Labelled Compounds

Pharmaceuticals