(4-bromo-1,2-phenylene)dimethanol
- Product Name
- (4-bromo-1,2-phenylene)dimethanol
- CAS No.
- 171011-37-3
- Chemical Name
- (4-bromo-1,2-phenylene)dimethanol
- Synonyms
- (4-Bromo-1,2-phenylene);1,2-Benzenedimethanol, 4-bromo-;(4-bromo-1,2-phenylene)dimethanol;[5-bromo-2-(hydroxymethyl)phenyl]methanol;[4-bromo-2-(hydroxymethyl)phenyl]methanol;[5-bromo-2-(hydroxymethyl)phenyl]methanol - [AC77970]
- CBNumber
- CB42516134
- Molecular Formula
- C8H9BrO2
- Formula Weight
- 217.06
- MOL File
- 171011-37-3.mol
(4-bromo-1,2-phenylene)dimethanol Property
- Melting point:
- 84 °C
- Boiling point:
- 361.8±32.0 °C(Predicted)
- Density
- 1.628±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 14.06±0.10(Predicted)
- Appearance
- White to off-white Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B696188
- Product name
- 4-Bromo-2-(hydroxymethyl)benzylalcohol
- Packaging
- 1g
- Price
- $120
- Updated
- 2021/12/16
- Product number
- X3856
- Product name
- 4-Bromo-2-(hydroxymethyl)benzylalcohol
- Packaging
- 5g
- Price
- $435
- Updated
- 2021/12/16
- Product number
- CM294591
- Product name
- (4-Bromo-1,2-phenylene)dimethanol
- Purity
- 95+%
- Packaging
- 10g
- Price
- $480
- Updated
- 2021/12/16
- Product number
- 171011373
- Product name
- (4-Bromo-1,2-phenylene)dimethanol
- Packaging
- 10g
- Price
- $543.78
- Updated
- 2021/12/16
- Product number
- JR6-L7217
- Product name
- (4-Bromo-1,2-Phenylene)Dimethanol
- Purity
- 96%
- Packaging
- 25g
- Price
- $1280
- Updated
- 2021/12/16
(4-bromo-1,2-phenylene)dimethanol Chemical Properties,Usage,Production
Synthesis
86-90-8
171011-37-3
General procedure for the synthesis of 4-bromo-2-(hydroxymethyl)benzyl alcohol from 5-bromoisobenzofuran-1,3-dione: To an anhydrous toluene solution of 5-bromoisobenzofuran-1,3-dione (106 mg, 0.47 mmol) was slowly added a toluene solution of 1 M diisobutylaluminum hydride (DIBAL-H) (3 mL, 3 mmol) under ice-bath cooling conditions. The reaction mixture was stirred at room temperature for 1.5 hours. Subsequently, 10% aqueous hydrochloric acid solution (0.7 mL) was slowly added at 0°C. The reaction mixture was diluted with toluene (1 mL) and continued to be stirred at room temperature for 1 hour. The reaction mixture was filtered through diatomaceous earth and extracted with ethyl acetate (20 mL x 3). The organic phases were combined, washed with saturated saline (10 mL), dried over anhydrous magnesium sulfate and concentrated under reduced pressure. The residue was purified by silica gel column chromatography (eluent: hexane/ethyl acetate = 1:1) to afford the target product 4-bromo-2-(hydroxymethyl)benzyl alcohol (89 mg, 91% yield) as a colorless solid with a melting point of 67-67.5 °C.
References
[1] Heterocycles, 2009, vol. 77, # 2, p. 991 - 1005
[2] Synlett, 2013, vol. 24, # 19, p. 2510 - 2514
[3] Research on Chemical Intermediates, 2013, vol. 39, # 1, p. 139 - 146
[4] Patent: EP1659129, 2006, A1. Location in patent: Page/Page column 100
[5] Patent: WO2017/87854, 2017, A1. Location in patent: Page/Page column 00315
(4-bromo-1,2-phenylene)dimethanol Preparation Products And Raw materials
Raw materials
Preparation Products
(4-bromo-1,2-phenylene)dimethanol Suppliers
- Tel
- 0551-66399836 18955197623
- sales@enlipharma.com
- Country
- China
- ProdList
- 1876
- Advantage
- 55
- Tel
- 400-164-7117 13681763483
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 39966
- Advantage
- 60
- Tel
- 021-11111111 11111111111
- Fax
- qq:546919421
- 546919421@qq.com
- Country
- China
- ProdList
- 3521
- Advantage
- 55
- Tel
- 021-60455363 18019463053
- Fax
- 50966098
- sales@coolpharm.com
- Country
- China
- ProdList
- 12346
- Advantage
- 58
- Tel
- 0371-88888888 272369594
- Fax
- QQ:272369594
- 2723695949@qq.com
- Country
- China
- ProdList
- 4960
- Advantage
- 50
- Tel
- 13817485796
- Fax
- QQ:895624079
- tim@wisacheampharm.com
- Country
- China
- ProdList
- 3592
- Advantage
- 58
- Tel
- 021-64340559 13651849907;
- Fax
- 021- 64345308
- xinyu_shi@jwypharmlab.com.cn
- Country
- China
- ProdList
- 12000
- Advantage
- 58
- Tel
- 028-86040038 13980902949;
- Fax
- 028-85149890
- market@dingdangchem.com
- Country
- China
- ProdList
- 1853
- Advantage
- 55
- Tel
- 0519-85528066 13775048983
- Fax
- 0519-85528066
- sales@hopschem.com
- Country
- China
- ProdList
- 31553
- Advantage
- 55
- Tel
- 028-83379370 13880556291
- Fax
- 028-87747383
- tcy@tcypharm.com
- Country
- China
- ProdList
- 7218
- Advantage
- 58
View Lastest Price from (4-bromo-1,2-phenylene)dimethanol manufacturers
- Product
- (4-bromo-1,2-phenylene)dimethanol 171011-37-3
- Price
- US $0.00-0.00/G
- Min. Order
- 10G
- Purity
- 98%+
- Supply Ability
- 100000kg per Month
- Release date
- 2023-08-11