Gadermandiol
- Product Name
- Gadermandiol
- CAS No.
- 107900-76-5
- Chemical Name
- Gadermandiol
- Synonyms
- Gadermandiol;GanoderManondiol;Lanosta-7,9(11)-dien-3-one,24,25-dihydroxy-, (24S)-;(5R,10S,13R,14R,17R)-17-[(2R,5S)-5,6-dihydroxy-6-methylheptan-2-yl]-4,4,10,13,14-pentamethyl-1,2,5,6,12,15,16,17-octahydrocyclopenta[a]phenanthren-3-one
- CBNumber
- CB42519746
- Molecular Formula
- C30H48O3
- Formula Weight
- 456.7
- MOL File
- 107900-76-5.mol
Gadermandiol Property
- Boiling point:
- 580.4±50.0 °C(Predicted)
- Density
- 1.07±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Powder
- pka
- 14.67±0.29(Predicted)
N-Bromosuccinimide Price
- Product number
- 300311
- Product name
- Ganodermanondiol
- Packaging
- 5mg
- Price
- $708
- Updated
- 2021/12/16
- Product number
- 4214
- Product name
- Ganodermanondiol
- Packaging
- 1mg
- Price
- $119
- Updated
- 2021/12/16
- Product number
- 4214
- Product name
- Ganodermanondiol
- Packaging
- 5mg
- Price
- $290
- Updated
- 2021/12/16
- Product number
- CFN99085
- Product name
- Ganodermanondiol
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $368
- Updated
- 2021/12/16
- Product number
- 4214
- Product name
- Ganodermanondiol
- Packaging
- 10mg
- Price
- $490
- Updated
- 2021/12/16
Gadermandiol Chemical Properties,Usage,Production
Uses
Ganodermanondiol is a melanogenesis inhibitor isolated from the Ganoderma lucidum[1].Ganodermanondiol exhibits potent cytoprotective effects on tert-butyl hydroperoxide-induced hepatotoxicity[2]. Ganodermanondiol shows significant anti-HIV-1 protease activity with an IC50 of 90 μM[3]. Ganodermanondiol exhibits a strong anticomplement activity against the classical pathway of the complement system with an IC50 of 41.7μM[4].
Definition
ChEBI: Ganodermanondiol is a triterpenoid.
References
[1] Kim JW, et al. Effects of Ganodermanondiol, a New Melanogenesis Inhibitor from the Medicinal Mushroom Ganoderma lucidum. Int J Mol Sci. 2016 Oct 27;17(11). DOI:10.3390/ijms17111798
[2] Li B, et al. Protective effect of ganodermanondiol isolated from the Lingzhi mushroom against tert-butyl hydroperoxide-induced hepatotoxicity through Nrf2-mediated antioxidant enzymes. Food Chem Toxicol. 2013 Mar;53:317-24. DOI:10.1016/j.fct.2012.12.016
[3] Min BS, et al. Triterpenes from the spores of Ganoderma lucidum and their inhibitory activity against HIV-1 protease. Chem Pharm Bull (Tokyo). 1998 Oct;46(10):1607-12. DOI:10.1248/cpb.46.1607
[4] Min BS, et al. Anticomplement activity of terpenoids from the spores of Ganoderma lucidum. Planta Med. 2001 Dec;67(9):811-4. DOI:10.1055/s-2001-18854
Gadermandiol Preparation Products And Raw materials
Raw materials
Preparation Products
Gadermandiol Suppliers
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View Lastest Price from Gadermandiol manufacturers
- Product
- Ganodermanondiol 107900-76-5
- Price
- US $0.00/mg
- Min. Order
- 5mg
- Purity
- ≥98%(HPLC)
- Supply Ability
- 10 g
- Release date
- 2020-04-13
- Product
- Gadermandiol 107900-76-5
- Price
- US $5.50/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 1kg-100kg
- Release date
- 2020-01-10